'en:generalized skin thickening (particularly over the trunk)'
(id=9092435 ; fe=en:generalized skin thickening (particularly over the trunk) ; type=1 ; niveau=200 ; luminosité=25 ; somme entrante=36221 creation date=2017-10-27 touchdate=2025-09-04 16:43:43.000)

≈ 1716 relations sortantes en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:capillary hemangioma (in 1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:capillary hemangioma (in 1 patient) | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:focal scalp defects with alopecia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal scalp defects with alopecia | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:large brownish scales on lower extremities (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large brownish scales on lower extremities (in some patients) | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:large nevus (greater than 10 cm) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large nevus (greater than 10 cm) | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:localized cutaneous necrobiosis lipoidica n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localized cutaneous necrobiosis lipoidica | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:minimal or absent scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:minimal or absent scarring | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:mottled pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mottled pigmentation | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:pain/tenderness of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pain/tenderness of skin | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:palmar erythema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar erythema | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:reduced axillary apocrine secretion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced axillary apocrine secretion | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:scalp erosions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp erosions | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:seborrheic dermatitis (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrheic dermatitis (1 family) | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:skin folds or creases (neck or forearm) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin folds or creases (neck or forearm) | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 43 / 1 -> en:white ash leaf-shaped macules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:white ash leaf-shaped macules | rel=r_associated | relid=0 | w=43 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:acrocyanosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acrocyanosis | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:albopapuloid lesions may occur n1=en:generalized skin thickening (particularly over the trunk) | n2=en:albopapuloid lesions may occur | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:atopic dermatitis/eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atopic dermatitis/eczema | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:blistering at acral sites n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering at acral sites | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:cutaneous syndactyly (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous syndactyly (less common) | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:generalized swelling/papules/lumps/masses n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized swelling/papules/lumps/masses | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:hyperpigmented rim with long fine hairs encircling the lesions (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented rim with long fine hairs encircling the lesions (in some patients) | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:insect bites n1=en:generalized skin thickening (particularly over the trunk) | n2=en:insect bites | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:keratoderma, palmoplantar, epidermolytic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma, palmoplantar, epidermolytic | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:mucosal lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mucosal lesions | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:no easy bruisability n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no easy bruisability | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:pale, sensitive skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pale, sensitive skin | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:posterior midline scalp defects n1=en:generalized skin thickening (particularly over the trunk) | n2=en:posterior midline scalp defects | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:prominent knuckle pads (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent knuckle pads (in some patients) | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:seborrheic dermatitis in infancy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrheic dermatitis in infancy | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:sensitivity to cold with paresthesias n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sensitivity to cold with paresthesias | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:skin atrophy (especially over hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin atrophy (especially over hands and feet) | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:skin dimple (lower back) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin dimple (lower back) | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:subcutaneous lipoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous lipoma | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:telangiectasias in both sun-exposed and sun-protected areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasias in both sun-exposed and sun-protected areas | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:thin, dry skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, dry skin | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 42 / 0.977 -> en:warty acanthomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:warty acanthomas | rel=r_associated | relid=0 | w=42 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:exfoliative dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:exfoliative dermatitis | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:glabrous skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:glabrous skin | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:hyperpigmentation of blistered skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation of blistered skin | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:hypopigmented macules, primarily on extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented macules, primarily on extremities | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:ichthyosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis (in some patients) | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:knuckle pads n1=en:generalized skin thickening (particularly over the trunk) | n2=en:knuckle pads | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:mild atrophic scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild atrophic scarring | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:mild hyperkeratosis of palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild hyperkeratosis of palms | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:pallor of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pallor of skin | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:palmoplantar keratoderma, with honeycomb pattern (in most patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, with honeycomb pattern (in most patients) | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:papillomatosis of affected area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis of affected area | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:periarticular subcutaneous nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:periarticular subcutaneous nodules | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:pigmentary abnormalities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentary abnormalities | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:poikiloderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poikiloderma | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:prominent scalp veins n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent scalp veins | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:sacral striae n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sacral striae | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:skin fissures (groin, axilla, neck) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin fissures (groin, axilla, neck) | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:stage 1 - skin erythema, vesicles, pustules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stage 1 - skin erythema, vesicles, pustules | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:thick calluses on soles of feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick calluses on soles of feet | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:thin, translucent skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, translucent skin | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 41 / 0.953 -> en:unilateral erythema and scaling (present at birth or soon after birth, face is spared) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:unilateral erythema and scaling (present at birth or soon after birth, face is spared) | rel=r_associated | relid=0 | w=41 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:absence of dermopathy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of dermopathy | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:discoid lupus in carriers or adults with mild disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:discoid lupus in carriers or adults with mild disease | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:focal palmoplantar keratoderma on weight-bearing areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal palmoplantar keratoderma on weight-bearing areas | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:giant pigmented nevi, often in lumbosacral region n1=en:generalized skin thickening (particularly over the trunk) | n2=en:giant pigmented nevi, often in lumbosacral region | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:harlequin fetus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:harlequin fetus | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:hyperpigmented nevi and streak n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented nevi and streak | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:hypopigmented macules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented macules | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:juvenile colloid milium n1=en:generalized skin thickening (particularly over the trunk) | n2=en:juvenile colloid milium | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:nevus flammeus (eyelids and nape of neck) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus flammeus (eyelids and nape of neck) | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:palmar pit n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar pit | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:papillomatosis, reticular on the periphery, 1 to 2-mm growing to 4-5-mm and coalescing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis, reticular on the periphery, 1 to 2-mm growing to 4-5-mm and coalescing | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:pterygia of groin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygia of groin (in some patients) | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:subcutaneous scalp cysts n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous scalp cysts | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 40 / 0.93 -> en:superficial, firm, circumscribed nodule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:superficial, firm, circumscribed nodule | rel=r_associated | relid=0 | w=40 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:abrasion/scratch/blister n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abrasion/scratch/blister | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:decreased urocanic acid in stratum corneum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased urocanic acid in stratum corneum | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:dimples (chin, buttocks) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dimples (chin, buttocks) | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:granulomatous dermatitis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:granulomatous dermatitis (in some patients) | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:ichthyosis of scalp and flexural areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis of scalp and flexural areas | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:laceration/cut n1=en:generalized skin thickening (particularly over the trunk) | n2=en:laceration/cut | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:large cafe au lait spots with irregular margins n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large cafe au lait spots with irregular margins | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:mast cell degranulation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mast cell degranulation | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:no scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no scarring | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:palmar keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar keratosis | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:papule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papule | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:skin tags on the upper part of the auricle n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin tags on the upper part of the auricle | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:suprapubic skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:suprapubic skin | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:tight, glistening facial skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tight, glistening facial skin | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:tumors leave pitting scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tumors leave pitting scars | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:vessels may form rounded nodules ('tufts') n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vessels may form rounded nodules ('tufts') | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 39 / 0.907 -> en:white skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:white skin | rel=r_associated | relid=0 | w=39 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:cleavage within basal keratinocytes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cleavage within basal keratinocytes | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:dry palmar skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry palmar skin | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:ecchymoses, congenital (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ecchymoses, congenital (in some patients) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:eczema (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (rare) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:facial hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial hyperpigmentation | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:fibroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fibroma | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:foot callus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:foot callus | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:hyperelastic skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperelastic skin (in some patients) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:hypohidrosis or anhidrosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis or anhidrosis (in some patients) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:hypopigmented skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented skin lesions | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:palmoplantar keratoderma, patchy (>50%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, patchy (>50%) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:seborrhea (35% of adults) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrhea (35% of adults) | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 38 / 0.884 -> en:variable involvement of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:variable involvement of palms and soles | rel=r_associated | relid=0 | w=38 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:abscess formation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abscess formation | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:baldness/losing hair n1=en:generalized skin thickening (particularly over the trunk) | n2=en:baldness/losing hair | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:cutaneous and mucosal skin tags n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous and mucosal skin tags | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:freckling may or may not be present n1=en:generalized skin thickening (particularly over the trunk) | n2=en:freckling may or may not be present | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:hyperkeratotic yellowish papules and plaques arranged linearly on palms and fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic yellowish papules and plaques arranged linearly on palms and fingers | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:hypopigmented macules on neck, chest, and back (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented macules on neck, chest, and back (in some patients) | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:hypoplastic fingertip epidermal ridges n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic fingertip epidermal ridges | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:increased wrinkles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased wrinkles | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:localised rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localised rash | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:loose skin at birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loose skin at birth | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:melanocytic skin tumors/papules, skin-colored to reddish-brown, dome-shaped or pedunculated, well circumscribed with an average size of 5 mm (in 2 families) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:melanocytic skin tumors/papules, skin-colored to reddish-brown, dome-shaped or pedunculated, well circumscribed with an average size of 5 mm (in 2 families) | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:palmar telangiectasias (described in 1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar telangiectasias (described in 1 family) | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:plexiform neurofibroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plexiform neurofibroma | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:pterygium of wrist, bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium of wrist, bilateral (in some patients) | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 37 / 0.86 -> en:slight erythema of face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:slight erythema of face | rel=r_associated | relid=0 | w=37 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:absent axonal flare response after intradermal histamine injection n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent axonal flare response after intradermal histamine injection | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:absent dermal ridges n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent dermal ridges | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:bald area on scalp (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bald area on scalp (in some patients) | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:bilateral single transverse palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bilateral single transverse palmar creases | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:candida diaper dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:candida diaper dermatitis | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:cutis aplasia, occipital n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis aplasia, occipital | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:darkly pigmented skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:darkly pigmented skin | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:eczema (face and flexural areas) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (face and flexural areas) | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:impetigo-like eruptions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:impetigo-like eruptions | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:light-sensitive dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:light-sensitive dermatitis | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:localized hives with erythema, edema, and pruritus after repetitive vibratory or stretching stimulation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localized hives with erythema, edema, and pruritus after repetitive vibratory or stretching stimulation | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:molluscum contagiosum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:molluscum contagiosum | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:normal sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal sweat glands | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:palmoplantar cutis laxa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar cutis laxa | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:papulosquamous erythematous plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papulosquamous erythematous plaques | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:perianal skin tags n1=en:generalized skin thickening (particularly over the trunk) | n2=en:perianal skin tags | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:photosensitivity (harderoporphyria and hcp) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:photosensitivity (harderoporphyria and hcp) | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:recurrent skin infections n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent skin infections | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:reddish discoloration, episodic, associated with pain n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reddish discoloration, episodic, associated with pain | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:reduced skin elasticity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced skin elasticity | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:scaling, hyperchromic spots on limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scaling, hyperchromic spots on limbs | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:seborrheic dermatitis of scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrheic dermatitis of scalp | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:small, pit-like, atrophic areas (0.25-2.0mm) predominantly on cheeks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small, pit-like, atrophic areas (0.25-2.0mm) predominantly on cheeks | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 36 / 0.837 -> en:stage 3 - skin hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stage 3 - skin hyperpigmentation | rel=r_associated | relid=0 | w=36 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:aberrant melanosome maturation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aberrant melanosome maturation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:abnormal alignment of collagen bundles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal alignment of collagen bundles | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:abnormal granulation tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal granulation tissue | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:absence of normal rete ridge pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of normal rete ridge pattern | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:absent-mild skin hyperextensibility n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent-mild skin hyperextensibility | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:acanthosis nigricans (neck, axilla, groin, periorbital region, perioral region) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans (neck, axilla, groin, periorbital region, perioral region) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:acanthosis nigricans, axillary (in male patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans, axillary (in male patient) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:acneiform lesions (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acneiform lesions (rare) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:acrocyanosis of the feet (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acrocyanosis of the feet (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:affects limbs and trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:affects limbs and trunk | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:angiokeratoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:angiokeratoma | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:angiokeratomas (soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:angiokeratomas (soles) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:angiomatous lesions on the fingers, persistent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:angiomatous lesions on the fingers, persistent | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:aplasia cutis of the scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis of the scalp | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:blistering occurs in clusters ('herpetiform', 'arcuate') n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering occurs in clusters ('herpetiform', 'arcuate') | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:blistering, recurrent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, recurrent | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:blisters and erosions after mechanical manipulation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blisters and erosions after mechanical manipulation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:burnett schwartz berberian syndrome n1=en:generalized skin thickening (particularly over the trunk) | n2=en:burnett schwartz berberian syndrome | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cafe au lait spots (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe au lait spots (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:clear gelatinous pterygia-like plaques of the nasal and temporal perilimbal bulbar conjunctiva n1=en:generalized skin thickening (particularly over the trunk) | n2=en:clear gelatinous pterygia-like plaques of the nasal and temporal perilimbal bulbar conjunctiva | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:congenital erythrokeratodermia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital erythrokeratodermia | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:congenital poikiloderma on face and exposed skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital poikiloderma on face and exposed skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:corns and callus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:corns and callus | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cutaneous telangiectases of face, upper chest, upper mid-back, upper extremities, and hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous telangiectases of face, upper chest, upper mid-back, upper extremities, and hands | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cutis laxa (infancy) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis laxa (infancy) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cutis marmorata (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata (rare) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cylindromas usually occur on the scalp may coalesce into large 'turban tumors' n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cylindromas usually occur on the scalp may coalesce into large 'turban tumors' | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:cysts may gradually increase in size n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts may gradually increase in size | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:decreased flexion creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased flexion creases | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:decreased intraepithelial nerve fiber density n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased intraepithelial nerve fiber density | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:deep palmar crease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep palmar crease | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:dermal ossification (osteoma cutis) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermal ossification (osteoma cutis) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:dermatitis (chronic or chronically relapsing, major feature) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis (chronic or chronically relapsing, major feature) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:dermatitis ichthyosiform n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis ichthyosiform | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:draining sinuses (late complication) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:draining sinuses (late complication) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:early freckle-like lesions in exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:early freckle-like lesions in exposed areas | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:early onset skin cancer (basal cell, squamous cell and malignant melanoma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:early onset skin cancer (basal cell, squamous cell and malignant melanoma) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:ecchymoses common n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ecchymoses common | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:ecchymosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ecchymosis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:eczema (perifollicular accentuation) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (perifollicular accentuation) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:episodic urticaria n1=en:generalized skin thickening (particularly over the trunk) | n2=en:episodic urticaria | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:erosion, generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erosion, generalized | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:excessive salt in sweat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:excessive salt in sweat | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:excessive skin wrinkling of palms and soles (in one patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:excessive skin wrinkling of palms and soles (in one patient) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:facial pallor n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial pallor | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:fine white scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine white scales | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:fine whitish scaling on face and trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine whitish scaling on face and trunk | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:finely wrinkled palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:finely wrinkled palms | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:flexion contractures of hands due to severe hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flexion contractures of hands due to severe hyperkeratosis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:flexural skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flexural skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:follicular hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular hyperkeratosis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:follows blaschko's lines n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follows blaschko's lines | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:generalized darkening of the skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized darkening of the skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:granulomatous dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:granulomatous dermatitis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:henoch-schoenlein purpura n1=en:generalized skin thickening (particularly over the trunk) | n2=en:henoch-schoenlein purpura | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:high sweat electrolyte n1=en:generalized skin thickening (particularly over the trunk) | n2=en:high sweat electrolyte | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hirsutism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hirsutism | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:honeycomb palmoplantar keratoderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:honeycomb palmoplantar keratoderma | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:horny papules (face, leg, buttocks) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:horny papules (face, leg, buttocks) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperhidrosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperkeratosis (especially extensor surfaces) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis (especially extensor surfaces) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperkeratosis and fissuring around orifices n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis and fissuring around orifices | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperkeratosis on soles of feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis on soles of feet | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperpigmented 2 to 5-mm macules mainly on the extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented 2 to 5-mm macules mainly on the extremities | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hyperpigmented skin patches (face, neck, trunk, limbs, lip, oral mucosa, palms, and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented skin patches (face, neck, trunk, limbs, lip, oral mucosa, palms, and soles) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hypohidrosis may be present n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis may be present | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hypopigmented spots (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented spots (less common) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:hypoplastic-absent sebaceous glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic-absent sebaceous glands | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:ichthyosis (in contiguous gene syndrome patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis (in contiguous gene syndrome patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:increased chloride levels in sweat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased chloride levels in sweat | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:increased number of skin folds (neck, abdomen, axillae) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased number of skin folds (neck, abdomen, axillae) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:jaundice (harderoporphyria) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (harderoporphyria) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:jaundice (in some) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (in some) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:jaundice (sometimes onset in the neonatal period) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (sometimes onset in the neonatal period) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:jaundice due to hemolytic anemia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice due to hemolytic anemia | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:jaundice, green n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice, green | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:knuckle pads on dorsal finger and toe joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:knuckle pads on dorsal finger and toe joints | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:lack of epidermal ridges on palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lack of epidermal ridges on palms and soles | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:larger brownish scaling on neck, buttocks, and legs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:larger brownish scaling on neck, buttocks, and legs | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:linear hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear hyperpigmentation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:linear or reticular hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear or reticular hyperpigmentation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:local swelling/papules/lump/mass n1=en:generalized skin thickening (particularly over the trunk) | n2=en:local swelling/papules/lump/mass | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:maculopapular rash, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:maculopapular rash, episodic | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mild diffuse ichthyosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild diffuse ichthyosis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mild eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild eczema | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mild scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild scarring | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mild-moderate bruisability n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild-moderate bruisability | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mild/severe skin hypopigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild/severe skin hypopigmentation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:milia (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:milia (rare) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:morbilliform eruption n1=en:generalized skin thickening (particularly over the trunk) | n2=en:morbilliform eruption | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mucocutaneous candidiasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mucocutaneous candidiasis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:mucosal lesions affecting all regions (i.e., oral, nasal, vaginal, anal, bladder, conjunctival regions) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mucosal lesions affecting all regions (i.e., oral, nasal, vaginal, anal, bladder, conjunctival regions) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:nevus, blue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus, blue | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:nodule show lipid-laden macrophages n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nodule show lipid-laden macrophages | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:non-glabrous skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:non-glabrous skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:non-purpuric punctate and linear erythematous rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:non-purpuric punctate and linear erythematous rash | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:non-scarring skin blistering (hands, feet, elbow, knee - onset in adolescence) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:non-scarring skin blistering (hands, feet, elbow, knee - onset in adolescence) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:normal numbers of sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal numbers of sweat glands | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:normal skin (no palmoplantar keratoderma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal skin (no palmoplantar keratoderma) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:onset birth-newborn period n1=en:generalized skin thickening (particularly over the trunk) | n2=en:onset birth-newborn period | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:other changes in skin color n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other changes in skin color | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:painless, ulcerating lesions of distal extremities, tongue, and lips n1=en:generalized skin thickening (particularly over the trunk) | n2=en:painless, ulcerating lesions of distal extremities, tongue, and lips | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:palmoplantar hyperlinearity, marked n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperlinearity, marked | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:palmoplantar keratoderma (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:palmoplantar keratoderma, mild (in homozygous patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, mild (in homozygous patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:palmoplantar pits n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar pits | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:patchy desquamation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:patchy desquamation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:patchy, reticular stains n1=en:generalized skin thickening (particularly over the trunk) | n2=en:patchy, reticular stains | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:peeling of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:peeling of skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:periorbital wrinkles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:periorbital wrinkles | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:petechiae (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:petechiae (less common) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:petechiae and purpura do not occur n1=en:generalized skin thickening (particularly over the trunk) | n2=en:petechiae and purpura do not occur | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:piebaldism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:piebaldism | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:plexiform neurofibroma (76%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plexiform neurofibroma (76%) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:poor wound healing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poor wound healing | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:port-wine stain n1=en:generalized skin thickening (particularly over the trunk) | n2=en:port-wine stain | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:prepuce n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prepuce | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:pretibial pigmented granulomatous plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pretibial pigmented granulomatous plaques | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:progressive cutaneous atrophy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progressive cutaneous atrophy | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:prominent fingertip pads n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent fingertip pads | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:prominent superficial blood vessels due to thin skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent superficial blood vessels due to thin skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:prurigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prurigo | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:psoriasiform lesions (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform lesions (rare) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:pterygia of neck (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygia of neck (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:pterygium (elbows and knees) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium (elbows and knees) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:punctate palmoplantar keratoderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punctate palmoplantar keratoderma | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:pustule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pustule | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:redundant skin folds on upper and lower limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant skin folds on upper and lower limbs | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:residual hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:residual hyperpigmentation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:sacral dimple (2 patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sacral dimple (2 patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:scales on scalp (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scales on scalp (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:sclerodermatous skin changes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sclerodermatous skin changes | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:sclerosis of digits (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sclerosis of digits (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:severe acne (23% of adults) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe acne (23% of adults) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:severe progressive ulceration of lower extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe progressive ulceration of lower extremities | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin blisters n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin blisters | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin derivative n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin derivative | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin dimple over apex of long bone angulation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin dimple over apex of long bone angulation | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin diseases, infectious n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin diseases, infectious | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin flushing, episodic, associated with pain n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin flushing, episodic, associated with pain | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin lesions follow the lines of blaschko n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin lesions follow the lines of blaschko | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin of female human body n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of female human body | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin of male human body n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of male human body | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:skin peeling/scaling (newborn) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin peeling/scaling (newborn) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:small areas of alopecia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small areas of alopecia | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:small nodular skin-tags n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small nodular skin-tags | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:soft tissue calcinosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft tissue calcinosis | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:speckled lentiginous nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:speckled lentiginous nevus | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:split anchoring plaques of desmosomes in the granular layer (transmission electron microscopy (tem)) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:split anchoring plaques of desmosomes in the granular layer (transmission electron microscopy (tem)) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:squamous epitheliomas, multiple n1=en:generalized skin thickening (particularly over the trunk) | n2=en:squamous epitheliomas, multiple | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:striated lichenoid keratoses in major flexural folds n1=en:generalized skin thickening (particularly over the trunk) | n2=en:striated lichenoid keratoses in major flexural folds | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:telangiectases (especially on tongue, lips, palate, fingers, face, conjunctiva, trunk, nail beds, and fingertips) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectases (especially on tongue, lips, palate, fingers, face, conjunctiva, trunk, nail beds, and fingertips) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:telangiectasia on lips and oral mucosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasia on lips and oral mucosa | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:telangiectasia on the cheeks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasia on the cheeks | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:thick skin (66%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick skin (66%) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:thick, indurated skin over entire body n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick, indurated skin over entire body | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:thin, wrinkled skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, wrinkled skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:transgradient palmoplantar keratoderma on dorsal hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transgradient palmoplantar keratoderma on dorsal hands and feet | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:transgredient extension of hyperkeratosis onto wrists (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transgredient extension of hyperkeratosis onto wrists (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:varicose veins (reported in 1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:varicose veins (reported in 1 family) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:verrucous hyperplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:verrucous hyperplasia | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:verrucous proliferation (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:verrucous proliferation (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:vertical crease in fourth interdigital space n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vertical crease in fourth interdigital space | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:widespread keratinized plaques (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:widespread keratinized plaques (in some patients) | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 35 / 0.814 -> en:wrinkled abdominal skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled abdominal skin | rel=r_associated | relid=0 | w=35 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:'orange peel' skin (large pores) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:'orange peel' skin (large pores) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:abnormal blistering of the skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal blistering of the skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:abscess of skin and/or subcutaneous tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abscess of skin and/or subcutaneous tissue | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:absent fingerprints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent fingerprints | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:acral keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acral keratosis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:annular lesions (3 mm to 1 cm in diameter) located on the face, neck, trunk and limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:annular lesions (3 mm to 1 cm in diameter) located on the face, neck, trunk and limbs | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:autoamputation of fifth toe, bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:autoamputation of fifth toe, bilateral (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:axillary apocrine gland hypoplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:axillary apocrine gland hypoplasia | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:axillary pterygia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:axillary pterygia | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:basal cell layer contains clumped keratin filaments n1=en:generalized skin thickening (particularly over the trunk) | n2=en:basal cell layer contains clumped keratin filaments | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:basal cell nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:basal cell nevus | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:bilateral single palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bilateral single palmar creases | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:bilateral transverse palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bilateral transverse palmar creases | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:blistering, generalized, recurrent (occurs after mild physical trauma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, generalized, recurrent (occurs after mild physical trauma) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:blistering, generalized, recurrent, severe (occurs after mild physical trauma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, generalized, recurrent, severe (occurs after mild physical trauma) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:blistering, mild (occurs mainly on ankles and feet and in response to trauma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, mild (occurs mainly on ankles and feet and in response to trauma) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:bright copper-red coloration of skin (in darker-skinned individuals) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bright copper-red coloration of skin (in darker-skinned individuals) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:brown, warty keratotic papules (trunk, scalp, forehead, flexural areas) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:brown, warty keratotic papules (trunk, scalp, forehead, flexural areas) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:brownish-black macules on dorsa of hands and feet (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:brownish-black macules on dorsa of hands and feet (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:bullous, pustular dermatitis of extremities, oral, anal, and genital areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bullous, pustular dermatitis of extremities, oral, anal, and genital areas | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cafe au lait spot n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe au lait spot | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cafe-au-lait spot (in 1/4 patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe-au-lait spot (in 1/4 patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cellulitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cellulitis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cellulitis over affected area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cellulitis over affected area | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:coarse, thick skin (especially upper face and scalp) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:coarse, thick skin (especially upper face and scalp) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:collagen-rich connective tissue nevi (dermatofibrosis lenticularis disseminata) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collagen-rich connective tissue nevi (dermatofibrosis lenticularis disseminata) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:collodion membrane at birth (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion membrane at birth (1 patient) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:collodion membrane at birth (in most patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion membrane at birth (in most patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:congenital absence of skin in some areas (aplasia cutis) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital absence of skin in some areas (aplasia cutis) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous 0.5 to 1.0 cm bluish and flesh-colored papules (rarely reported) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous 0.5 to 1.0 cm bluish and flesh-colored papules (rarely reported) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous capillary malformation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous capillary malformation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous dimples (knees, elbows, shoulders) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous dimples (knees, elbows, shoulders) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous hyperpigmentation (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous hyperpigmentation (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous infections (staphylococcus aureus, herpes simplex) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous infections (staphylococcus aureus, herpes simplex) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous nevi flammei (limbs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous nevi flammei (limbs) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutaneous vascular malformation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous vascular malformation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutis gyrata n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis gyrata | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cutis marmorata (in some) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata (in some) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:cysts may disappear on their own (10%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts may disappear on their own (10%) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:dark skin pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dark skin pigmentation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:decreased sweating (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased sweating (1 patient) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:deep foot creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep foot creases | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:depigmented spots n1=en:generalized skin thickening (particularly over the trunk) | n2=en:depigmented spots | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:dermatitis, infectious, due to immunodeficiency n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis, infectious, due to immunodeficiency | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:diaper rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diaper rash | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:dry, scaly skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry, scaly skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:dry, stiff skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry, stiff skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:epidermolysis bullosa simplex n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermolysis bullosa simplex | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:epidermolytic hyperkeratosis, mild n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermolytic hyperkeratosis, mild | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erysipelas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erysipelas | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythema, mild to moderate (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema, mild to moderate (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythema, residual painless n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema, residual painless | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythematous skin blotching n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous skin blotching | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythroderma (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythroderma (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythroderma, generalized congenital n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythroderma, generalized congenital | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythroderma, moderate to severe n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythroderma, moderate to severe | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:erythroderma, psoriasiform n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythroderma, psoriasiform | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:excessive skin wrinkling on dorsum of hands and fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:excessive skin wrinkling on dorsum of hands and fingers | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:external ear n1=en:generalized skin thickening (particularly over the trunk) | n2=en:external ear | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:eyelid structure n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eyelid structure | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:facial or extensor involvement in infants and children (major feature) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial or extensor involvement in infants and children (major feature) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:fine erythrodermic scales, generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine erythrodermic scales, generalized | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:fine greyish-white scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine greyish-white scales | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:fissure in skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fissure in skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:flexural lichenification in adults (major feature) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flexural lichenification in adults (major feature) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:focal dermal aplasia/hypoplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal dermal aplasia/hypoplasia | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:focal friction-related palmoplantar hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal friction-related palmoplantar hyperkeratosis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:follicular atrophoderma affecting the dorsa of the hands and feet, the face, and extensor surfaces of the elbows and knees n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular atrophoderma affecting the dorsa of the hands and feet, the face, and extensor surfaces of the elbows and knees | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:follicular keratosis on elbows and knees n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular keratosis on elbows and knees | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:follicular papule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular papule | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:folliculitis of the scalp, trunk, and extensor surfaces of the extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:folliculitis of the scalp, trunk, and extensor surfaces of the extremities | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:fragile skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fragile skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:frequent staphylococcus aureus infections n1=en:generalized skin thickening (particularly over the trunk) | n2=en:frequent staphylococcus aureus infections | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:frontal hirsutism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:frontal hirsutism | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:frostbitten hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:frostbitten hands | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:generalized dry skin with fine scaling and sparing of face (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized dry skin with fine scaling and sparing of face (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:generalized erythema (inflammatory type b) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized erythema (inflammatory type b) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:generalized skin wrinkling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized skin wrinkling | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:glabellar hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:glabellar hemangioma | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hand dermatitis (non-allergic, irritant) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hand dermatitis (non-allergic, irritant) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:histology shows exterior zone of densely packed, small basophilic cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:histology shows exterior zone of densely packed, small basophilic cells | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyaline deposition in dermis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyaline deposition in dermis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperhidrosis (hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis (hands and feet) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperkeratosis of skin at nipples and umbilicus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of skin at nipples and umbilicus | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperkeratosis of the palms (seen in recessive form) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of the palms (seen in recessive form) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperkeratotic papules in blistered areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic papules in blistered areas | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperkeratotic plaques on anterior knee area (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic plaques on anterior knee area (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperkeratotic plaques on anterolateral ankle area (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic plaques on anterolateral ankle area (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperpigmentation (in patients with kit mutations) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation (in patients with kit mutations) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperpigmentation (knuckles, elbows, axillae, areolae, pubic area) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation (knuckles, elbows, axillae, areolae, pubic area) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hyperpigmented/hypopigmented macules (dorsum hands and feet, face) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented/hypopigmented macules (dorsum hands and feet, face) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hypertrophic keloid-like lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrophic keloid-like lesions | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hypohidrosis, localized, often on face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis, localized, often on face | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hypopigmentation in a reticular pattern primarily on flexural skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmentation in a reticular pattern primarily on flexural skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:hypopigmented streaks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented streaks | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:ichthyoses n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyoses | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:increased mast cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased mast cells | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:increased pigmented nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased pigmented nevi | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:intolerant of heat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intolerant of heat | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:irregular hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:irregular hyperpigmentation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:jaundice, neonatal or in early childhood n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice, neonatal or in early childhood | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:keratosis follicularis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis follicularis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:larger lamellar scales (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:larger lamellar scales (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:lentigines may be absent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lentigines may be absent | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:lentigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lentigo | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:leukoplakia (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:leukoplakia (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:linear arrays of macular hyperkeratoses in flexural areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear arrays of macular hyperkeratoses in flexural areas | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:linear nevus sebaceous, often in midfacial area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear nevus sebaceous, often in midfacial area | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:localized cellulitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localized cellulitis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:loose, elastic skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loose, elastic skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:loss of subcutaneous fat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loss of subcutaneous fat | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:maculae can be a few millimeters to several centimeters in diameter and can be surrounded by pale halo with punctate red spot in middle n1=en:generalized skin thickening (particularly over the trunk) | n2=en:maculae can be a few millimeters to several centimeters in diameter and can be surrounded by pale halo with punctate red spot in middle | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:malignant neoplasm of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:malignant neoplasm of skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:marked skin pallor n1=en:generalized skin thickening (particularly over the trunk) | n2=en:marked skin pallor | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:mild hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild hyperkeratosis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:multiple gingival papules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple gingival papules | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:multiple, small punctate keratoses (palms and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple, small punctate keratoses (palms and soles) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:necrotic skin ulcers (in 1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:necrotic skin ulcers (in 1 patient) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:neonatal purpura fulminans n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal purpura fulminans | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:nevi flammei (philtrum, nape of neck, forehead) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevi flammei (philtrum, nape of neck, forehead) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:nevus/mole n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus/mole | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:no cutaneous photosensitivity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no cutaneous photosensitivity | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:no hyperhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no hyperhidrosis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:no mucosal vesicles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no mucosal vesicles | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:non pruritic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:non pruritic | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:normal sweat electrolytes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal sweat electrolytes | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:numerous 'confetti-like' scattered patches of normal skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:numerous 'confetti-like' scattered patches of normal skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:numerous pigmented freckles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:numerous pigmented freckles | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:other localized skin infection n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other localized skin infection | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:other symptom/complaint skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other symptom/complaint skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:palmoplantar cutis gyrata n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar cutis gyrata | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:palmoplantar hyperkeratosis, mild (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperkeratosis, mild (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:palmoplantar keratoderma (mild in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma (mild in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:palmoplantar keratoderma, mild (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, mild (rare) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:palmoplantar keratodermia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratodermia | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:panniculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:panniculitis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:papillomatosis over edematous areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis over edematous areas | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:parakeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:parakeratosis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pediculosis/other skin infestation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pediculosis/other skin infestation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pigmentation abnormalities (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentation abnormalities (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pilomatrixoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pilomatrixoma | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pityriasis rosea n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pityriasis rosea | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:porokeratoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:porokeratoma | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:premature aging, mild n1=en:generalized skin thickening (particularly over the trunk) | n2=en:premature aging, mild | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:progression of skin lesions - n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progression of skin lesions - | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:prominent venous markings n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent venous markings | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pruritic ichthyosis (onset birth to first several months) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritic ichthyosis (onset birth to first several months) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:psoriasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pterygia of axillae (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygia of axillae (in some patients) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:pterygium of elbow (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium of elbow (rare) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:punctate keratoses (palms and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punctate keratoses (palms and soles) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:purpuric rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:purpuric rash | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:rash erythematous n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash erythematous | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:reticulate hyperpigmented macules which darken over time and appear initially on dorsa of hands and feet but progress to flexor aspects of proximal extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate hyperpigmented macules which darken over time and appear initially on dorsa of hands and feet but progress to flexor aspects of proximal extremities | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:reticulate skin pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate skin pigmentation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:scleroderma-like skin, especially of face and distal extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scleroderma-like skin, especially of face and distal extremities | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:seborrheic dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrheic dermatitis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:sharp midline demarcation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sharp midline demarcation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:skin atrophy (over nose and scalp sutural areas) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin atrophy (over nose and scalp sutural areas) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:skin foreign body n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin foreign body | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:skin lesions are usually symmetrical n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin lesions are usually symmetrical | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:skin wrinkling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin wrinkling | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:skin wrinkling (limited to dorsum of hands and feet and abdomen) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin wrinkling (limited to dorsum of hands and feet and abdomen) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:sparing of flexure areas, palms, and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sparing of flexure areas, palms, and soles | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:spotty hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spotty hyperpigmentation | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:steatocystoma multiplex n1=en:generalized skin thickening (particularly over the trunk) | n2=en:steatocystoma multiplex | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:stiff skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stiff skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:strawberry nevus of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:strawberry nevus of skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:stretched skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stretched skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:subcutaneous connective tissue nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous connective tissue nevi | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:subungual fibroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subungual fibroma | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:telangiectases (palms, soles, scalp, scrotum, legs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectases (palms, soles, scalp, scrotum, legs) | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:tendinous xanthomas presenting after age 20 years in heterozygotes, during first 4 years of life in homozygotes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tendinous xanthomas presenting after age 20 years in heterozygotes, during first 4 years of life in homozygotes | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:thin skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:umbilical bleeding after birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:umbilical bleeding after birth | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:varicosity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:varicosity | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:vasculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vasculitis | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:verrucae (warts), multiple n1=en:generalized skin thickening (particularly over the trunk) | n2=en:verrucae (warts), multiple | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:vertical creases of plantar surface between first and second toes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vertical creases of plantar surface between first and second toes | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:vesicles on scalp and skin filled with clear fluid and less than 1cm in diameter n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vesicles on scalp and skin filled with clear fluid and less than 1cm in diameter | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:white scaling skin, most prominent over upper and lower extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:white scaling skin, most prominent over upper and lower extremities | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:wide, thin scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wide, thin scars | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:wrinkled face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled face | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:wrinkled skin over fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled skin over fingers | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:yellow-orange colored skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:yellow-orange colored skin | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 34 / 0.791 -> en:yellow, papular lesions of the lip, soft palate, pharynx n1=en:generalized skin thickening (particularly over the trunk) | n2=en:yellow, papular lesions of the lip, soft palate, pharynx | rel=r_associated | relid=0 | w=34 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:'ice-pick marks' n1=en:generalized skin thickening (particularly over the trunk) | n2=en:'ice-pick marks' | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:abnormal pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal pigmentation | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:abnormally pigmented macules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormally pigmented macules | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:absence of subcutaneous fat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of subcutaneous fat | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:absent phalangeal crease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent phalangeal crease | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:absent skin pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent skin pigmentation | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:acne n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acne | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:angiokeratoma corporis diffusum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:angiokeratoma corporis diffusum | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:angioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:angioma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:anhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:anhydrotic ectodermal dysplasias n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhydrotic ectodermal dysplasias | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:antecubital webbing (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:antecubital webbing (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:aplasia of the sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia of the sweat glands | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:arborescent papillomas (axillae, periumbilical area, anus, vulva) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:arborescent papillomas (axillae, periumbilical area, anus, vulva) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:atrophic scar n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic scar | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:atrophic scarring (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic scarring (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:atrophic scarring, severe n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic scarring, severe | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:atypical nevi often present in non-sun exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atypical nevi often present in non-sun exposed areas | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:axillary pterygium, bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:axillary pterygium, bilateral (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:blistering of hands, elbows, feet, knees n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering of hands, elbows, feet, knees | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cafe au lait spots, multiple n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe au lait spots, multiple | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:calcified, ulcerating nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:calcified, ulcerating nodules | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cellulitis, recurrent (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cellulitis, recurrent (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:central atrophic area with peripheral keratotic ridge n1=en:generalized skin thickening (particularly over the trunk) | n2=en:central atrophic area with peripheral keratotic ridge | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:comedo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:comedo | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:common wart n1=en:generalized skin thickening (particularly over the trunk) | n2=en:common wart | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:confetti-like hypopigmented macules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:confetti-like hypopigmented macules | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:congenital nonbullous ichthyosiform erythroderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital nonbullous ichthyosiform erythroderma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:crusting erythematous dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:crusting erythematous dermatitis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cutaneous leiomyomata (heterozygote carriers) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous leiomyomata (heterozygote carriers) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cutaneous mastocytosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous mastocytosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cutis marmorata telangiectatica congenita n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata telangiectatica congenita | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cyanosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cyanosis due to congenital heart defect n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis due to congenital heart defect | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cylindromas, multiple (usually occur on the scalp, but may also occur on the face, trunk, and extremities) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cylindromas, multiple (usually occur on the scalp, but may also occur on the face, trunk, and extremities) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:cysts are firm and smooth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts are firm and smooth | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:decreased number of sweat pores n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased number of sweat pores | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:decreased palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased palmar creases | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:degeneration of basal epidermal cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:degeneration of basal epidermal cells | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:dermatitis acidemica n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis acidemica | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:dermatitis, atopic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis, atopic | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:dermo-epidermal junction n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermo-epidermal junction | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:dimples (over bowed limbs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dimples (over bowed limbs) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:discoid rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:discoid rash | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:doughy skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:doughy skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:dry, bumpy skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry, bumpy skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:epithelial cyst n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epithelial cyst | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:erythematous indurated plaques on the shins n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous indurated plaques on the shins | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:erythematous rash (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous rash (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:erythematous skin lesions in infancy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous skin lesions in infancy | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:erythroderma, patchy, on cheeks and chin (1/4 patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythroderma, patchy, on cheeks and chin (1/4 patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:eschar formation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eschar formation | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:exanthema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:exanthema | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:exophytic, red lesion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:exophytic, red lesion | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:extreme skin fragility n1=en:generalized skin thickening (particularly over the trunk) | n2=en:extreme skin fragility | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:facial erythema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial erythema | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:facial xanthomatous eruptions (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial xanthomatous eruptions (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:fear of cancer of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fear of cancer of skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:fibrofolliculoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fibrofolliculoma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:finger subcutaneous nodule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:finger subcutaneous nodule | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:flushing attacks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flushing attacks | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:generalized rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized rash | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:giant plaque of porokeratosis ptychotropica n1=en:generalized skin thickening (particularly over the trunk) | n2=en:giant plaque of porokeratosis ptychotropica | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:gilbert disease (disorder) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:gilbert disease (disorder) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hair may not be present on the nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hair may not be present on the nevus | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hemangiomata, especially thorax and upper abdomen n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangiomata, especially thorax and upper abdomen | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hemorrhagic blisters n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemorrhagic blisters | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperhidrosis of plantar surface (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis of plantar surface (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperkeratosis of perianal areas, auricles, knuckles, knees, and ankles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of perianal areas, auricles, knuckles, knees, and ankles | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperkeratosis over affected area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis over affected area | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperkeratosis pilaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis pilaris | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperpigmentation associated with increased adrenocorticotropic hormone (acth) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation associated with increased adrenocorticotropic hormone (acth) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hyperpigmented patches (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented patches (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hypertrophic scarring (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrophic scarring (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hypoplastic dermal ridges n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic dermal ridges | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:hypoplastic flexion creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic flexion creases | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:icterus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:icterus | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:infra-orbital crease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:infra-orbital crease | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:irregular annular keratotic lesions with slightly elevated borders, located primarily on the face but also distributed on the chest and forearms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:irregular annular keratotic lesions with slightly elevated borders, located primarily on the face but also distributed on the chest and forearms | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:jaundice, neonatal (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice, neonatal (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:keratosis pilaris of arms and legs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis pilaris of arms and legs | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:light complexion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:light complexion | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:light skin pigmentation compared to unaffected sibs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:light skin pigmentation compared to unaffected sibs | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:lighter skin color n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lighter skin color | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:lipofibroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lipofibroma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:lipohypoplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lipohypoplasia | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:livedo racemosa (usually on trunk and/or lower extremities) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:livedo racemosa (usually on trunk and/or lower extremities) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:longitudinal hyperkeratotic lesions along flexor surface of each finger, extending to palm n1=en:generalized skin thickening (particularly over the trunk) | n2=en:longitudinal hyperkeratotic lesions along flexor surface of each finger, extending to palm | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:loose volor skin of hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loose volor skin of hands | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:maceration of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:maceration of palms and soles | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:marked bruisability n1=en:generalized skin thickening (particularly over the trunk) | n2=en:marked bruisability | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:mild hypopigmentation (in light-skinned individuals) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild hypopigmentation (in light-skinned individuals) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:milia of upper face and ears (infancy) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:milia of upper face and ears (infancy) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:milky white skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:milky white skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:mulitple papules (1-2 mm skin colored and hyperpigmented) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mulitple papules (1-2 mm skin colored and hyperpigmented) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:multiple nevi (up to hundreds) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple nevi (up to hundreds) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:multiple pterygia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple pterygia | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:multiple, asymptomatic dermal cysts (trunk, proximal extremities, neck, axillae, inguinal region, scalp) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple, asymptomatic dermal cysts (trunk, proximal extremities, neck, axillae, inguinal region, scalp) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:neonatal jaundice n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal jaundice | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:nevus flammeus of the forehead n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus flammeus of the forehead | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:no hemorrhage n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no hemorrhage | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:no ichthyosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no ichthyosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:no inflammatory or bullous skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no inflammatory or bullous skin lesions | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:no tanning n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no tanning | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:occasional neurofibromas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:occasional neurofibromas | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:other infectious skin disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other infectious skin disease | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:palmoplantar epidermolytic hyperkeratosis along blaschko lines (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar epidermolytic hyperkeratosis along blaschko lines (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:palmoplantar hyperhidrosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperhidrosis (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:papules enlarge centrifugally to form central atrophic area with an irregular peripheral keratotic ridge n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papules enlarge centrifugally to form central atrophic area with an irregular peripheral keratotic ridge | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:perianal erythema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:perianal erythema | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:perinasal or perioral nonhealing crusting of the skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:perinasal or perioral nonhealing crusting of the skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:peristomal skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:peristomal skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:pigmentary abnormalities (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentary abnormalities (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:pityriasis alba n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pityriasis alba | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:planar xanthomas in homozygotes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:planar xanthomas in homozygotes | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:premature aging (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:premature aging (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:progeric skin changes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progeric skin changes | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:progressive cutis verticis gyrata n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progressive cutis verticis gyrata | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:prolonged capillary refill n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prolonged capillary refill | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:prominent superficial venous pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent superficial venous pattern | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:prominent veins on scalp, trunk, and/or extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent veins on scalp, trunk, and/or extremities | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:pseudoainhum of fifth toes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pseudoainhum of fifth toes | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:psoriasis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasis (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:punch-like skin defects n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punch-like skin defects | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:purpura n1=en:generalized skin thickening (particularly over the trunk) | n2=en:purpura | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:pustular psoriasis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pustular psoriasis (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:raised, firm, hairless posterior scalp nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:raised, firm, hairless posterior scalp nodules | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:recurrent bacterial skin infections n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent bacterial skin infections | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:recurrent skin abscesses (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent skin abscesses (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:red, cracking, peeling skin at birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:red, cracking, peeling skin at birth | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:red, raised, scaly skin patches (elbows, knees, scalp) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:red, raised, scaly skin patches (elbows, knees, scalp) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:reduced subcutaneous adipose tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced subcutaneous adipose tissue | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:reduced sweating of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced sweating of palms and soles | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:residual erythema after healing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:residual erythema after healing | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:severe atopic dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe atopic dermatitis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:severe cystic acne n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe cystic acne | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:severe photosensitivity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe photosensitivity | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:shiny, taut, erythematous skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:shiny, taut, erythematous skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:skin biopsy shows noncaseating granulomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin biopsy shows noncaseating granulomas | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:skin fragility with non-scarring blistering n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin fragility with non-scarring blistering | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:skin tags on chest n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin tags on chest | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:skin tags on genitalia (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin tags on genitalia (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:soft skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:sparse dermal ridges (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sparse dermal ridges (rare) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:spiky hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spiky hyperkeratosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:spiradenoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spiradenoma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:squamous pityriasiform appearance of scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:squamous pityriasiform appearance of scalp | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:striated keratoderma of palms (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:striated keratoderma of palms (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:sunburn after short exposure to sun n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sunburn after short exposure to sun | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:superficial skin peeling (limited to dorsa of hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:superficial skin peeling (limited to dorsa of hands and feet) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:symptom/complaint nails n1=en:generalized skin thickening (particularly over the trunk) | n2=en:symptom/complaint nails | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:tanning possible n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tanning possible | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:telangiectases (especially on tongue, lips, palate, face, conjunctiva, trunk, nail beds, fingers, and finger pads) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectases (especially on tongue, lips, palate, face, conjunctiva, trunk, nail beds, fingers, and finger pads) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:tendency to overheat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tendency to overheat | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:thick, relatively tight skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick, relatively tight skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:thickened nuchal skin fold n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickened nuchal skin fold | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:thickened skin over the elbows and along the fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickened skin over the elbows and along the fingers | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:thin, hypotrophic skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, hypotrophic skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:thin, transparent skin (hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, transparent skin (hands and feet) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:transient, migratory sharply outlined erythema (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transient, migratory sharply outlined erythema (in some patients) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:tuberous xanthoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tuberous xanthoma | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:wrinkly skin (13 of 22) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkly skin (13 of 22) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:xerosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:xerosis | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:xerosis (buttocks, extensor surfaces of extremities) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:xerosis (buttocks, extensor surfaces of extremities) | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 32 / 0.744 -> en:yellow subcutaneous tissue covered by thin, scaly skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:yellow subcutaneous tissue covered by thin, scaly skin | rel=r_associated | relid=0 | w=32 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:'orange peel' skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:'orange peel' skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:3. lax, wrinkled skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:3. lax, wrinkled skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:aberrant skin dimples (elbows and knees) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aberrant skin dimples (elbows and knees) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:abnormal dermatoglyphic pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal dermatoglyphic pattern | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:abnormal sensitivity to uvb wavelengths by radiation monochromator skin testing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal sensitivity to uvb wavelengths by radiation monochromator skin testing | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:absence of skin creases over distal interphalangeal (dip) joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of skin creases over distal interphalangeal (dip) joints | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:anhidrosis of the trunk and limbs 100% of the time n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis of the trunk and limbs 100% of the time | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:anhidrosis over skin lesions (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis over skin lesions (rare) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:anhidrosis, patchy, in some patients n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis, patchy, in some patients | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:animal/human bite n1=en:generalized skin thickening (particularly over the trunk) | n2=en:animal/human bite | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:atrophic hyperpigmented streaks on face and neck n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic hyperpigmented streaks on face and neck | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:atrophic scarring (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic scarring (less common) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:atrophic skin over ears n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic skin over ears | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:autoamputation of digits n1=en:generalized skin thickening (particularly over the trunk) | n2=en:autoamputation of digits | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:axillary freckling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:axillary freckling | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:basal cell carcinoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:basal cell carcinoma | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:bluish skin nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bluish skin nodules | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:brownish macular and lentiginous lesions, disseminated, present on extremities, trunk, and neck n1=en:generalized skin thickening (particularly over the trunk) | n2=en:brownish macular and lentiginous lesions, disseminated, present on extremities, trunk, and neck | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:calcification may occur n1=en:generalized skin thickening (particularly over the trunk) | n2=en:calcification may occur | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:chin dimples n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chin dimples | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:chronic candidiasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chronic candidiasis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:chronic skin ulcer n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chronic skin ulcer | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:clavus formation (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:clavus formation (rare) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:collodion membrane at birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion membrane at birth | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:congenital absence of skin on some areas (aplasia cutis) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital absence of skin on some areas (aplasia cutis) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:connective tissue nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:connective tissue nevus | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:contact dermatitis and other eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:contact dermatitis and other eczema | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:cutaneous syndactyly n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous syndactyly | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:cyanosis due to respiratory insufficiency n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis due to respiratory insufficiency | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:cyanosis during episodes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis during episodes | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:cyst occur most often on the scalp (89%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyst occur most often on the scalp (89%) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:cyst of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyst of skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:darkening of periorificial areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:darkening of periorificial areas | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:decreased viscoelasticity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased viscoelasticity | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:deep palmar creases (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep palmar creases (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:deep skin ulcers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep skin ulcers | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dermatitis herpetiformis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis herpetiformis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dermatographism (dermatographic urticaria) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatographism (dermatographic urticaria) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dermatomycoses n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatomycoses | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dermatophytosis, chronic deep dermatophytosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatophytosis, chronic deep dermatophytosis (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:diffuse skin wrinkling (especially dorsa of hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse skin wrinkling (especially dorsa of hands and feet) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dimple overlying knee n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dimple overlying knee | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:distal painless ulcers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:distal painless ulcers | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:dyshidrosis [pompholyx] n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dyshidrosis [pompholyx] | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:edema of dorsum of hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:edema of dorsum of hands and feet | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:epidermal hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermal hyperkeratosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:epidermolysis bullosa dystrophica n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermolysis bullosa dystrophica | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:erdheim-chester disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erdheim-chester disease | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:erythema nodosum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema nodosum | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:erythematous malar rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous malar rash | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:extensive cutaneous involvement rarely occurs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:extensive cutaneous involvement rarely occurs | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:facial milia tend to disappear in adulthood n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial milia tend to disappear in adulthood | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:facial trichilemmomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial trichilemmomas | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:fades in adolescence n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fades in adolescence | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:fibrosis over affected area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fibrosis over affected area | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:fine white or greyish-white scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine white or greyish-white scales | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:focal hyperkeratosis of dorsum of hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal hyperkeratosis of dorsum of hands and feet | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:follicular atrophoderma (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular atrophoderma (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:freckles in sun-exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:freckles in sun-exposed areas | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:frontal cutaneous lipoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:frontal cutaneous lipoma | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:furrowed facial skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:furrowed facial skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:genital porokeratosis, localized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:genital porokeratosis, localized | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:giant pigmented hairy nevus, often in lumbosacral distribution n1=en:generalized skin thickening (particularly over the trunk) | n2=en:giant pigmented hairy nevus, often in lumbosacral distribution | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:gingival hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:gingival hyperkeratosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hard scaly skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hard scaly skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hemorrhagic palmar and plantar macules (uncommon) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemorrhagic palmar and plantar macules (uncommon) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperextensible skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperextensible skin (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperhidrosis occurs during pain episodes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis occurs during pain episodes | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperkeratosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperkeratosis, focal, on the palms and soles (in adulthood in some) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis, focal, on the palms and soles (in adulthood in some) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperkeratosis, particularly on palms and soles of feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis, particularly on palms and soles of feet | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperkeratotic dark-brown papules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic dark-brown papules | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperpigmentation in a reticular pattern primarily on flexural skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation in a reticular pattern primarily on flexural skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hyperpigmented/hypopigmented macules (trunk, extremities, occasionally face) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented/hypopigmented macules (trunk, extremities, occasionally face) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypertrophy of skin of soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrophy of skin of soles | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypohidrosis (in patients with hsan2d) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis (in patients with hsan2d) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypohidrosis/hyperhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis/hyperhidrosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypopigmentation spots n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmentation spots | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypopigmented skin patch n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented skin patch | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:hypoplastic pilosebaceous units n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic pilosebaceous units | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:ichthyosis (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis (rare) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:ichthyosis, diffuse lamellar n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis, diffuse lamellar | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:impaired would healing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:impaired would healing | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:increased fine wrinkles (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased fine wrinkles (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:inguinal freckling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:inguinal freckling | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:jaundice (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:keloid formation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keloid formation | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:keratoacanthoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoacanthoma | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:keratosis palmaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis palmaris | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:keratosis pilaris (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis pilaris (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:keratosis plantaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis plantaris | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:large adherent dark pigmented scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large adherent dark pigmented scales | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lentiginosis, generalized (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lentiginosis, generalized (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lesions appear on the trunk and limbs but the face, palms, soles, and mucosa are spared n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions appear on the trunk and limbs but the face, palms, soles, and mucosa are spared | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lesions become soft and paler with age n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions become soft and paler with age | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lichenification n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenification | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lichenified skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenified skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:linear plaque-like scales (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear plaque-like scales (1 family) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:linear porokeratosis (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear porokeratosis (rare) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:livedo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:livedo | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:livedo reticularis (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:livedo reticularis (1 patient) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:longer retraction time after stretching n1=en:generalized skin thickening (particularly over the trunk) | n2=en:longer retraction time after stretching | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:loose, redundant skin on fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loose, redundant skin on fingers | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:lymphatic vessels present at the periphery of lesion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lymphatic vessels present at the periphery of lesion | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:macular hypopigmented whorls, streaks, and patches n1=en:generalized skin thickening (particularly over the trunk) | n2=en:macular hypopigmented whorls, streaks, and patches | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:maculopapular eruption, diffuse n1=en:generalized skin thickening (particularly over the trunk) | n2=en:maculopapular eruption, diffuse | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:mature adipocytes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mature adipocytes | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:mechanically fragile skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mechanically fragile skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:migratory ichthyosiform dermatosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:migratory ichthyosiform dermatosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:mildly extensible skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mildly extensible skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:moderate scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:moderate scarring | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:multiple, flat, skin-colored warty papules (2-4mm in diameter on dorsum hands, feet, knees, and elbows) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple, flat, skin-colored warty papules (2-4mm in diameter on dorsum hands, feet, knees, and elbows) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:netherton syndrome n1=en:generalized skin thickening (particularly over the trunk) | n2=en:netherton syndrome | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:no abnormalities of sweating n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no abnormalities of sweating | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:no erythema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no erythema | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:nodule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nodule | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:non-actinic disseminated superficial porokeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:non-actinic disseminated superficial porokeratosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:orthostatic acrocyanosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:orthostatic acrocyanosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:other disorders of the skin and subcutaneous tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other disorders of the skin and subcutaneous tissue | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:other injury to skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other injury to skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:painful bluish-red papules or nodules (fingers, toes, nose, cheek, ears) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:painful bluish-red papules or nodules (fingers, toes, nose, cheek, ears) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:palmoplantar keratosis with erythema and scale n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratosis with erythema and scale | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:papillomatosis, confluent centrally, erythematous turning brown later n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis, confluent centrally, erythematous turning brown later | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:papules, firm, flat or dome-shaped, skin-colored some with a hair at or just outside the periphery and/or telangiectatic surface n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papules, firm, flat or dome-shaped, skin-colored some with a hair at or just outside the periphery and/or telangiectatic surface | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:periorificial hyperkeratotic lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:periorificial hyperkeratotic lesions | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:petechiae, congenital systemic (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:petechiae, congenital systemic (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pigmented lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmented lesions | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pilonidal cyst/fistula n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pilonidal cyst/fistula | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:plaque-like scaling skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plaque-like scaling skin lesions | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:poor healing with abnormal scarring (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poor healing with abnormal scarring (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:poor sweating in response to heat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poor sweating in response to heat | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:prominent superficial veins n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent superficial veins | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:prominent vasculature (nose and forehead) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent vasculature (nose and forehead) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pruritic eczematous lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritic eczematous lesions | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pruritus (inflammatory type b) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus (inflammatory type b) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pruritus (major feature) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus (major feature) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pterygium of bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium of bilateral (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:punctate palmoplantar hyperkeratosis (later onset) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punctate palmoplantar hyperkeratosis (later onset) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:pyramidal skinfold of halluces n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pyramidal skinfold of halluces | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:raised, scaly, and/or hyperkeratotic areas of skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:raised, scaly, and/or hyperkeratotic areas of skin (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:rare skin cancers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rare skin cancers | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:rash (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:rash, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash, episodic | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:recurrent infections due to painless trauma and ulceration n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent infections due to painless trauma and ulceration | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:redundant folds n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant folds | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:residual slightly atrophic scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:residual slightly atrophic scarring | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:reticular hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticular hyperpigmentation | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:reticular skin pigmentation (classic feature, nola3 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticular skin pigmentation (classic feature, nola3 patient) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:reticulate hyperpigmentation composed of 1- to 5-mm light brown spots with clearly defined borders that may coalesce n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate hyperpigmentation composed of 1- to 5-mm light brown spots with clearly defined borders that may coalesce | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:rhytide of forehead n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rhytide of forehead | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:s. epidermidis only microorganism isolated n1=en:generalized skin thickening (particularly over the trunk) | n2=en:s. epidermidis only microorganism isolated | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:scabies and other acariases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scabies and other acariases | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:scalp defect n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp defect | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:scalp defect (aplasia cutis congenita) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp defect (aplasia cutis congenita) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:scalp sinus formation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp sinus formation | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:sclerotic soft tissue over affected bones n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sclerotic soft tissue over affected bones | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:scrotum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scrotum | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:sensitive skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sensitive skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:severe bullous blistering lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe bullous blistering lesions | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:single transverse palmar crease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:single transverse palmar crease | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin atrophy, diffuse, in older patients n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin atrophy, diffuse, in older patients | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin cell n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin cell | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin mottling due to poor perfusion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin mottling due to poor perfusion | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin necrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin necrosis | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin of scalp and neck n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of scalp and neck | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin of the face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of the face | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin of the upper limb and shoulder n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of the upper limb and shoulder | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:skin rough n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin rough | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:slow-healing wounds due to painless injuries n1=en:generalized skin thickening (particularly over the trunk) | n2=en:slow-healing wounds due to painless injuries | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:small, yellow papules (mouth, neck, axilla, elbows, groin, periumbilical region) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small, yellow papules (mouth, neck, axilla, elbows, groin, periumbilical region) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:smooth, thin, dry skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:smooth, thin, dry skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:spheroids n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spheroids | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:spontaneous, non-scarring healing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spontaneous, non-scarring healing | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:subcutaneous lipomatous tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous lipomatous tissue | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:subepidermal capillary ectasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subepidermal capillary ectasia | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:tan macules on glans penis and penile shaft n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tan macules on glans penis and penile shaft | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:telangiectasia, particularly of the fingerpads and lips n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasia, particularly of the fingerpads and lips | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:thick skin on face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick skin on face | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:thick, waxy skin of palms and soles with well-defined erythematous border n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick, waxy skin of palms and soles with well-defined erythematous border | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:tight, rigid skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tight, rigid skin | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:tinea capitis, severe or recurrent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tinea capitis, severe or recurrent | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:transient painful erysipelas-like lesions on lower leg and ankle n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transient painful erysipelas-like lesions on lower leg and ankle | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:transverse distal crease across palm n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transverse distal crease across palm | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:ulcerations of distal extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcerations of distal extremities | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:ulcers often lead to infection and amputation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcers often lead to infection and amputation | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:urticaria pigmentosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:urticaria pigmentosa | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:usually present on skin of neck, shoulders, or trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:usually present on skin of neck, shoulders, or trunk | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:velvety texture n1=en:generalized skin thickening (particularly over the trunk) | n2=en:velvety texture | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:vitiligo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vitiligo | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:warts, generalized (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:warts, generalized (in some patients) | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 31 / 0.721 -> en:white dermatographism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:white dermatographism | rel=r_associated | relid=0 | w=31 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:absence of interphalangeal creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of interphalangeal creases | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:absent distal interphalangeal creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent distal interphalangeal creases | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:acral violaceous plaques and nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acral violaceous plaques and nodules | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:acrokeratosis verruciformis-like lesions on dorsum of hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acrokeratosis verruciformis-like lesions on dorsum of hands | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:affects distal limb and scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:affects distal limb and scalp | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:aplasia cutis congenita n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis congenita | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:atrophic condition of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic condition of skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:atypical nevi (>5mm with irregular edge and pigmentation) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atypical nevi (>5mm with irregular edge and pigmentation) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:bilateral palmar simian creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bilateral palmar simian creases | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:blistering erythematous rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering erythematous rash | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:blistering may be generalized or localized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering may be generalized or localized | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:blotching pigmentation of the skin (in older children) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blotching pigmentation of the skin (in older children) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:burning sensation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:burning sensation | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:calcinosis cutis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:calcinosis cutis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:candidiasis, chronic mucocutaneous n1=en:generalized skin thickening (particularly over the trunk) | n2=en:candidiasis, chronic mucocutaneous | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:chronic eczematoid rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chronic eczematoid rash | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:chronic granulomatous nodules (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chronic granulomatous nodules (rare) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:circumferential skin creases on neck (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:circumferential skin creases on neck (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:congenital ichthyosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital ichthyosis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:congenital localized absence of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital localized absence of skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:creamy white skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:creamy white skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:crouzon syndrome with acanthosis nigricans (disorder) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:crouzon syndrome with acanthosis nigricans (disorder) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:cutaneous leiomyosarcoma (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous leiomyosarcoma (rare) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:cylindromas, multiple (face, trunk and extremities) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cylindromas, multiple (face, trunk and extremities) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:decreased histidase activity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased histidase activity | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:decreased skin stiffness n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased skin stiffness | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:derived from hair matrix cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:derived from hair matrix cells | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:dermatophytosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatophytosis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:diffuse erythematous maculopapular rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse erythematous maculopapular rash | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:distinct odor of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:distinct odor of palms and soles | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:distorted triradii of palmar skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:distorted triradii of palmar skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:dorsal hand wrinkling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dorsal hand wrinkling | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ectodermal dystrophy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ectodermal dystrophy | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ectodermal symptoms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ectodermal symptoms | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:eczema-like lesions (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema-like lesions (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:elbow dimples n1=en:generalized skin thickening (particularly over the trunk) | n2=en:elbow dimples | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:enhanced secondary hyperalgesia and flare response on mustard oil application n1=en:generalized skin thickening (particularly over the trunk) | n2=en:enhanced secondary hyperalgesia and flare response on mustard oil application | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:epidermal derivative n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermal derivative | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erosion lesion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erosion lesion | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erosions, congenital, on dorsal and/or plantar surface of hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erosions, congenital, on dorsal and/or plantar surface of hands and feet | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erythematous nodular skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous nodular skin lesions | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erythematous papular skin eruption (infancy) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous papular skin eruption (infancy) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erythematous, irregular netlike pattern of vessels n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous, irregular netlike pattern of vessels | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:erythrodermic psoriasis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythrodermic psoriasis (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:excessive skin folds n1=en:generalized skin thickening (particularly over the trunk) | n2=en:excessive skin folds | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:familial progressive hyperpigmentation and hypopigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:familial progressive hyperpigmentation and hypopigmentation | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:fat pad n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fat pad | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:fingerprints, absence of n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fingerprints, absence of | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:fissuring of palms and/or soles in hot or cold weather n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fissuring of palms and/or soles in hot or cold weather | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:fistula formation (late complication) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fistula formation (late complication) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:focal hyperkeratosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal hyperkeratosis (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:follicular hyperkeratosis of occipital scalp, nape of neck, and extensor surfaces of upper limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular hyperkeratosis of occipital scalp, nape of neck, and extensor surfaces of upper limbs | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:folliculitis (back, axilla, pubic region) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:folliculitis (back, axilla, pubic region) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:fragility with blistering (neonatal onset) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fragility with blistering (neonatal onset) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:generalized bruising tendency n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized bruising tendency | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:generalized peeling skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized peeling skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:generalized pustular psoriasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized pustular psoriasis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:granular layer hyperplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:granular layer hyperplasia | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:healed areas are atrophic and hypopigmented n1=en:generalized skin thickening (particularly over the trunk) | n2=en:healed areas are atrophic and hypopigmented | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hemangioma, cavernous n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangioma, cavernous | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hyperhidrosis disorder n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis disorder | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hyperhidrosis palmaris et plantaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperhidrosis palmaris et plantaris | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hyperkeratosis over edematous areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis over edematous areas | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hyperpigmented macules of variable size and shape located in a symmetrical pattern primarily on face, neck, trunk, and dorsa of hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented macules of variable size and shape located in a symmetrical pattern primarily on face, neck, trunk, and dorsa of hands and feet | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hyperpigmented patches of skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented patches of skin (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hypertrichosis (scalp, arms, legs, back) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrichosis (scalp, arms, legs, back) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hypohidrosis (in most patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis (in most patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hypohidrosis and/or heat intolerance n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis and/or heat intolerance | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hypopigmentation of surgical scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmentation of surgical scars | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:hypopigmented skin patches on arms (vitiligo) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented skin patches on arms (vitiligo) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ichthyosiform dermatosis, diffuse generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosiform dermatosis, diffuse generalized | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ichthyosis, generalized, with involvement of flexural folds n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis, generalized, with involvement of flexural folds | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:infraorbital fold (dennie-morgan lines) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:infraorbital fold (dennie-morgan lines) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ingrown toenail/other disease of nail n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ingrown toenail/other disease of nail | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:intracytoplasmic vacuoles in basal keratinocytes (with negative oil red o-staining) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intracytoplasmic vacuoles in basal keratinocytes (with negative oil red o-staining) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:jaundice (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (less common) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:jaundice, intermittent (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice, intermittent (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:junctional epidermolysis bullosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:junctional epidermolysis bullosa | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:keratoderma, palmoplantar, diffuse n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma, palmoplantar, diffuse | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:large dark plate-like scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large dark plate-like scales | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:lesions follow the lines of blaschko n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions follow the lines of blaschko | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:less pressure required to lift skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:less pressure required to lift skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:lichenified lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenified lesions | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:linear epidermal nevus (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear epidermal nevus (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:loose redundant skin (especially of dorsum of hands and feet and anterior abdominal wall) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:loose redundant skin (especially of dorsum of hands and feet and anterior abdominal wall) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:lymphangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lymphangioma | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:macular hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:macular hemangioma | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:melanocytic nevus of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:melanocytic nevus of skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:migratory rashes, painful n1=en:generalized skin thickening (particularly over the trunk) | n2=en:migratory rashes, painful | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:moderate to severe acne n1=en:generalized skin thickening (particularly over the trunk) | n2=en:moderate to severe acne | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:most evident on lower legs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:most evident on lower legs | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:multiple lentigines n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple lentigines | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:multiple nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple nevi | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:multiple pigmented moles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple pigmented moles | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:multiple, red-blue, soft, compressible vascular papules or macules (especially on trunk or upper arms) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple, red-blue, soft, compressible vascular papules or macules (especially on trunk or upper arms) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:neonatal collodion skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal collodion skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:neonatal cyanosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal cyanosis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:nevus flammus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus flammus | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:normal scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal scarring | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:numerous congenital melanocytic nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:numerous congenital melanocytic nevi | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:occasional cafe-au-lait spots n1=en:generalized skin thickening (particularly over the trunk) | n2=en:occasional cafe-au-lait spots | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:other benign neoplasm of skin, unspecified n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other benign neoplasm of skin, unspecified | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:other/unspecified neoplasm skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other/unspecified neoplasm skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:pale-gray skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pale-gray skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:palmar hyperhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar hyperhidrosis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:palmar nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar nevi | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:palmoplantar hyperlinearity, marked (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperlinearity, marked (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:palmoplantar keratoderma, diffuse (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, diffuse (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:palms, soles, and oral mucosa are not involved n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palms, soles, and oral mucosa are not involved | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:peau d'orange n1=en:generalized skin thickening (particularly over the trunk) | n2=en:peau d'orange | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:periorbital hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:periorbital hyperpigmentation | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:photosensitivity of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:photosensitivity of skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:pilonidal cyst n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pilonidal cyst | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:pits of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pits of palms and soles | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:poorly developed palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poorly developed palmar creases | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:porokeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:porokeratosis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:positive skin test reaction to seminal fluid n1=en:generalized skin thickening (particularly over the trunk) | n2=en:positive skin test reaction to seminal fluid | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:profuse pigmented skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:profuse pigmented skin lesions | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:proliferation of spindle cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:proliferation of spindle cells | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:pruritic hyperkeratotic scars (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritic hyperkeratotic scars (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:pruritus of skin lesions, severe n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus of skin lesions, severe | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:psoriasiform dermatitis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform dermatitis (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:psoriasiform rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform rash | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:psoriasiform skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform skin lesions | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:psoriasis (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasis (rare) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:recurrent skin abscesses n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent skin abscesses | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:red mucosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:red mucosa | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:redundant connective tissue n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant connective tissue | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:reticular pigmentation pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticular pigmentation pattern | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:reticulated pigmentation (seen in recessive form) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulated pigmentation (seen in recessive form) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:rubbery feel of the nose and chin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rubbery feel of the nose and chin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:scleroderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scleroderma | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:sebaceous cysts (buttocks and perineum) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sebaceous cysts (buttocks and perineum) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:single, bilateral, symmetric papular/nodular lesion in the midline plantar region of the heel (0.5 - 1 cm diameter) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:single, bilateral, symmetric papular/nodular lesion in the midline plantar region of the heel (0.5 - 1 cm diameter) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:skin appendage structure n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin appendage structure | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:skin structure of back n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin structure of back | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:skin structure of ear n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin structure of ear | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:smooth, waxy, thick skin over palms and soles, desquamating in large flakes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:smooth, waxy, thick skin over palms and soles, desquamating in large flakes | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:soft and lax skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft and lax skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:soft thin skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft thin skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:soft, doughy skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft, doughy skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:soft, redundant skin (especially facial) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft, redundant skin (especially facial) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:soft, thin skin (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft, thin skin (1 family) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:steatocystomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:steatocystomas | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:sterile pustules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sterile pustules | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:streaks and whorls n1=en:generalized skin thickening (particularly over the trunk) | n2=en:streaks and whorls | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:subcutaneous nontender firm nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous nontender firm nodules | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:symptom/complaint of skin texture n1=en:generalized skin thickening (particularly over the trunk) | n2=en:symptom/complaint of skin texture | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:systematized epidermal nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:systematized epidermal nevus | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:telangiectasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasis | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:thick skin (74%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick skin (74%) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:thick, calloused skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick, calloused skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:thickened, furrowed skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickened, furrowed skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:thin translucent skin with prominent venous patterning n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin translucent skin with prominent venous patterning | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:tight, shiny skin over the forearms and hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tight, shiny skin over the forearms and hands | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:transitional zone of cells with gradual loss of nuclei n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transitional zone of cells with gradual loss of nuclei | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:ulcers, distal, painless, due to sensory neuropathy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcers, distal, painless, due to sensory neuropathy | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:uric acid tophi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:uric acid tophi | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:webbing of fingers (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:webbing of fingers (rare) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:well-circumscribed peeling of the skin on the extremities and neck (easily elicited by moisture and minor trauma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:well-circumscribed peeling of the skin on the extremities and neck (easily elicited by moisture and minor trauma) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:woolly hair nevus (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:woolly hair nevus (in some patients) | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:wrinkly skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkly skin | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 30 / 0.698 -> en:xanthoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:xanthoma | rel=r_associated | relid=0 | w=30 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:1. yellowish, flat papules (neck, antecubital and popliteal fossae, axillae, inguinal, and periumbilical areas) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:1. yellowish, flat papules (neck, antecubital and popliteal fossae, axillae, inguinal, and periumbilical areas) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:absent dorsal skin creases over affected joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absent dorsal skin creases over affected joints | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:accumulation of melanosomes in melanocytes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:accumulation of melanosomes in melanocytes | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:acne inverse (predominantly affecting armpit, groin, inner thigh, perianal and perineal, submammary, and buttock regions) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acne inverse (predominantly affecting armpit, groin, inner thigh, perianal and perineal, submammary, and buttock regions) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:acneform facial lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acneform facial lesions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:antecubial webbing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:antecubial webbing | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:aplasia/hypoplastia of the eccrine sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia/hypoplastia of the eccrine sweat glands | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:atopy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atopy | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:atrophic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:atrophic | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:blistering skin lesions, recurrent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering skin lesions, recurrent | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:blood vessel structure of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blood vessel structure of skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:bluish-red border demarcating transition to normal skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bluish-red border demarcating transition to normal skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:bulla n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bulla | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cafe-au-lait spots may or may not be present n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe-au-lait spots may or may not be present | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cafe-au-lait spots on chest and abdomen (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe-au-lait spots on chest and abdomen (rare) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:calluses on weight-bearing areas of soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:calluses on weight-bearing areas of soles | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:capillary malformations, small, multiple, diffuse n1=en:generalized skin thickening (particularly over the trunk) | n2=en:capillary malformations, small, multiple, diffuse | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cerebriform connective tissue nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cerebriform connective tissue nevus | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:chronic folliculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chronic folliculitis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cigarette-paper scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cigarette-paper scars | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:circumferential skin creases on extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:circumferential skin creases on extremities | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:circumscribed transparent membrane on the scalp vertex may be ulcerated (other areas of the body are rarely involved) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:circumscribed transparent membrane on the scalp vertex may be ulcerated (other areas of the body are rarely involved) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:coarse skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:coarse skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:collodion membrane at birth (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion membrane at birth (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:collodion skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:collodion skin changes ichthyosis pigmentary abnormalities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion skin changes ichthyosis pigmentary abnormalities | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cutaneous albinism, tyrosinase-positive n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous albinism, tyrosinase-positive | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cutaneous lichen amyloidosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous lichen amyloidosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cutaneous melanoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous melanoma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cutaneous vasculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous vasculitis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:cyanosis (25%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis (25%) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:dark pigmentation of knees and dorsum of hands and feet n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dark pigmentation of knees and dorsum of hands and feet | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:dermis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:diaphoresis (with pheochromocytoma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diaphoresis (with pheochromocytoma) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:dilated scalp veins radiating from periphery of scalp defect n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dilated scalp veins radiating from periphery of scalp defect | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:diminished sweating n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diminished sweating | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:doughy skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:doughy skin (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:dystrophic scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dystrophic scarring | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:eczema (in rare mutation carriers unaffected by a hematologic malignancy) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (in rare mutation carriers unaffected by a hematologic malignancy) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:edema, generalized perinatal (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:edema, generalized perinatal (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:epidermis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:epidermoid inclusion cysts n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermoid inclusion cysts | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:episodic cold-triggered erythrocyanosis of toes and fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:episodic cold-triggered erythrocyanosis of toes and fingers | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:epithelioid and spindle cell nevus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epithelioid and spindle cell nevus | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:erythematous squamous skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous squamous skin lesions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:eyelid margin cysts (apocrine hidrocystoma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eyelid margin cysts (apocrine hidrocystoma) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:facial telangiectasia in butterfly midface distribution (exacerbated by sun) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial telangiectasia in butterfly midface distribution (exacerbated by sun) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:fair skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fair skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:fetal pads of digits n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fetal pads of digits | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:fine white or light brown scales on scalp, face, trunk, and limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine white or light brown scales on scalp, face, trunk, and limbs | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:fine whitish scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine whitish scales | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:fine, reticulate skin pigmentation (trunk, palm, and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine, reticulate skin pigmentation (trunk, palm, and soles) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:follicular hyperkeratotic papules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular hyperkeratotic papules | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:freckled skin (in some less dark-skinned individuals) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:freckled skin (in some less dark-skinned individuals) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:generalized hypopigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized hypopigmentation | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:generalized ichthyosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized ichthyosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:granuloma annulare n1=en:generalized skin thickening (particularly over the trunk) | n2=en:granuloma annulare | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:greasy skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:greasy skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hemangiomatous branchial clefts (extend along sternocleidomastoid muscle) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangiomatous branchial clefts (extend along sternocleidomastoid muscle) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:herpes simplex infections n1=en:generalized skin thickening (particularly over the trunk) | n2=en:herpes simplex infections | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:herpes zoster disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:herpes zoster disease | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hidradenitis suppurativa (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hidradenitis suppurativa (rare) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:honeycomb keratoderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:honeycomb keratoderma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratosis (palms, soles, elbows, knees) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis (palms, soles, elbows, knees) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratosis in the area of joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis in the area of joints | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratosis of pressure sites of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of pressure sites of palms and soles | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratosis of the palms and soles and esophageal papillomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of the palms and soles and esophageal papillomas | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratotic cutaneous vascular lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic cutaneous vascular lesions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratotic micropapules over dorsum of interphalangeal joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic micropapules over dorsum of interphalangeal joints | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperkeratotic porokeratosis (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic porokeratosis (rare) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperpigmentation in flexure areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation in flexure areas | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hyperpigmented skin lesions (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented skin lesions (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hypohidrosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:hypopigmentation (family a) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmentation (family a) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:ichthyosis hystrix n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis hystrix | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:impetigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:impetigo | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:inguinal pterygium, bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:inguinal pterygium, bilateral (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:intermittent generalized erythematous papular rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intermittent generalized erythematous papular rash | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:jaundice during episodes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice during episodes | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:keratoderma of soles at pressure points n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma of soles at pressure points | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:keratoderma, striated, on palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma, striated, on palms | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:keratotic plaques (palms) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratotic plaques (palms) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:langerhans cell n1=en:generalized skin thickening (particularly over the trunk) | n2=en:langerhans cell | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:lesions are often brownish colored n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions are often brownish colored | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:lesions occur mainly on extremities, scalp, neck, and trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions occur mainly on extremities, scalp, neck, and trunk | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:linear skin defects on face and neck (in both patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear skin defects on face and neck (in both patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:localized symmetric fixed, yellow- or red-brown hyperkeratotic plaques (extensor surface of extremities, buttocks, and lateral trunk) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localized symmetric fixed, yellow- or red-brown hyperkeratotic plaques (extensor surface of extremities, buttocks, and lateral trunk) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:lymphedema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lymphedema | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:midfrontal capillary hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:midfrontal capillary hemangioma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:midline facial capillary hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:midline facial capillary hemangioma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:mild skin hyperextensibility n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild skin hyperextensibility | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:milia (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:milia (less common) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:multiple nevi (face and torso) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple nevi (face and torso) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:multiple papules (milium-like, comedo-like) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple papules (milium-like, comedo-like) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:multiple skin tags n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple skin tags | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:multiple small nevi (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple small nevi (rare) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:neurofibromas may or may not be present n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neurofibromas may or may not be present | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:neurofibromas, cutaneous (86%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neurofibromas, cutaneous (86%) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:no ability to tan n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no ability to tan | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:no palmoplantar hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no palmoplantar hyperkeratosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:no skin hyperelasticity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no skin hyperelasticity | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:occurs in linear distribution n1=en:generalized skin thickening (particularly over the trunk) | n2=en:occurs in linear distribution | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:orthokeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:orthokeratosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:painful, fleshy papules or nodules (hands, scalp, ears, perinasal area) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:painful, fleshy papules or nodules (hands, scalp, ears, perinasal area) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:palmar wrinkling n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar wrinkling | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:palmar xanthomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar xanthomas | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:palmoplantar hyperkeratosis, severe n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperkeratosis, severe | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:paradoxical sweating response (sweating induced by cold exposure, inability to sweat in hot weather) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:paradoxical sweating response (sweating induced by cold exposure, inability to sweat in hot weather) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:partial anhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:partial anhidrosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:patchy vitiligo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:patchy vitiligo | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:perineal intertrigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:perineal intertrigo | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:photosensitivity bullous dermatitis (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:photosensitivity bullous dermatitis (1 patient) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:pigmentary abnormalities along the lines of blaschko n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentary abnormalities along the lines of blaschko | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:pigmentation abnormalities (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentation abnormalities (1 family) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:plantar blistering n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar blistering | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:plantar hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar hyperkeratosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:poorly defined palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poorly defined palmar creases | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:porokeratosis, disseminated superficial actinic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:porokeratosis, disseminated superficial actinic | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:postauricular crescent-shaped hypoplastic skin lesion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:postauricular crescent-shaped hypoplastic skin lesion | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:postoperative hemorrhage n1=en:generalized skin thickening (particularly over the trunk) | n2=en:postoperative hemorrhage | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:progressive generalized skin erosions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progressive generalized skin erosions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:progressive vitiligo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progressive vitiligo | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:pseudoxanthomatous skin lesions (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pseudoxanthomatous skin lesions (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:pyoderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pyoderma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:pyoderma gangrenosum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pyoderma gangrenosum | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:raynaud phenomenon n1=en:generalized skin thickening (particularly over the trunk) | n2=en:raynaud phenomenon | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:redundant skin in infancy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant skin in infancy | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:reticulated skin pigmentation, predominantly on face, neck, chest, arms (94% male patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulated skin pigmentation, predominantly on face, neck, chest, arms (94% male patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:reticulolinear skin defects over face and neck (4/4 patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulolinear skin defects over face and neck (4/4 patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:sacral dimple n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sacral dimple | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:schwannoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:schwannoma | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin atrophy over affected bones n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin atrophy over affected bones | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin dimples on upper thighs (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin dimples on upper thighs (1 patient) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin hypopigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin hypopigmentation | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin of part of limb n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of part of limb | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin of the axilla n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of the axilla | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin of the lower limb and hip n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of the lower limb and hip | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin part n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin part | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:skin tag n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin tag | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:small papules on sun-exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small papules on sun-exposed areas | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:small pterygia (axillary, popliteal) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small pterygia (axillary, popliteal) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:soft with easy bruising (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft with easy bruising (in some patients) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:sparse axillary and facial hair n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sparse axillary and facial hair | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:spontaneous hematomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spontaneous hematomas | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:stage 2 - skin papules, verrucous lesions, hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stage 2 - skin papules, verrucous lesions, hyperkeratosis | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:stasis ulcers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stasis ulcers | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:subcutaneous lipomas, well-circumscribed and painful n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous lipomas, well-circumscribed and painful | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:telangiectases in sun-exposed and nonexposed skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectases in sun-exposed and nonexposed skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:telangiectatic lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectatic lesions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:thick skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:thick, loose, doughy skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick, loose, doughy skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:thickening of the skin over the palms and soles (nola3 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickening of the skin over the palms and soles (nola3 patient) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:thin, hyperpigmented skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, hyperpigmented skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:thin, velvety skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin, velvety skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:tumors appear most often on sun-exposed regions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tumors appear most often on sun-exposed regions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:ulcers, distal, due to sensory neuropathy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcers, distal, due to sensory neuropathy | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:velvety skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:velvety skin | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:venous angiectasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:venous angiectasia | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:vesicular lesions, congenital bilateral, between ear and corner of mouth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vesicular lesions, congenital bilateral, between ear and corner of mouth | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:vesiculopustular lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vesiculopustular lesions | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:vitiligo (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vitiligo (rare) | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 29 / 0.674 -> en:well-defined erythematous border n1=en:generalized skin thickening (particularly over the trunk) | n2=en:well-defined erythematous border | rel=r_associated | relid=0 | w=29 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:1-5mm dark lentigines (especially neck and trunk) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:1-5mm dark lentigines (especially neck and trunk) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:acanthosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:acral punctate keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acral punctate keratosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:anhidrosis (in patients with hsan2d) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis (in patients with hsan2d) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:annular erythematous edematous plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:annular erythematous edematous plaques | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:aplasia cutis congenita on trunk or limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis congenita on trunk or limbs | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:blanching of the fingers in response to cold n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blanching of the fingers in response to cold | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:blistering of palms in hot weather (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering of palms in hot weather (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:capillary malformations, commonly on face or neck, rarely on mucosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:capillary malformations, commonly on face or neck, rarely on mucosa | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:carbuncle/furuncle n1=en:generalized skin thickening (particularly over the trunk) | n2=en:carbuncle/furuncle | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:chilblains n1=en:generalized skin thickening (particularly over the trunk) | n2=en:chilblains | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:collodion membrane, self-healing (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:collodion membrane, self-healing (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:congenital symmetrical palmoplantar keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital symmetrical palmoplantar keratosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:connective tissue dysplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:connective tissue dysplasia | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutaneous candidiasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous candidiasis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutaneous piloleiomyomas (may be single or multiple) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous piloleiomyomas (may be single or multiple) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutis laxa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis laxa | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutis laxa (especially hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis laxa (especially hands and feet) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutis marmorata n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cutis marmorata (45%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata (45%) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cyanosis due to methemoglobinemia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cyanosis due to methemoglobinemia | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:cysts occur less commonly on any part of the body where hair grows n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts occur less commonly on any part of the body where hair grows | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:decreased sweating due to autonomic dysfunction n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased sweating due to autonomic dysfunction | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:deep skin creases in toes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep skin creases in toes | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dependent acrocyanosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dependent acrocyanosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dermatitis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dermatitis, infectious, due to immunodeficiency impetigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis, infectious, due to immunodeficiency impetigo | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dermatitis, symmetric pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermatitis, symmetric pattern | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:difficulty grasping or holding objects n1=en:generalized skin thickening (particularly over the trunk) | n2=en:difficulty grasping or holding objects | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:diffuse pigmentary skin mottling, mild, on trunk and proximal limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse pigmentary skin mottling, mild, on trunk and proximal limbs | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:diffuse yellow-orange non-epidermolytic hyperkeratosis on palms and soles (palmoplantar keratoderma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse yellow-orange non-epidermolytic hyperkeratosis on palms and soles (palmoplantar keratoderma) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:discrete 2 to 5-mm hyper- and hypopigmented macules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:discrete 2 to 5-mm hyper- and hypopigmented macules | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:doughy or puffy skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:doughy or puffy skin (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dry, thick skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry, thick skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:dysseborrheic dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dysseborrheic dermatitis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:easier stretching n1=en:generalized skin thickening (particularly over the trunk) | n2=en:easier stretching | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:easy bruising (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:easy bruising (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:eccrine poroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eccrine poroma | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:ectodermal dysplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ectodermal dysplasia | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:eczema (8 of 23) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (8 of 23) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:eczema, severe n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema, severe | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:edema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:edema | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:elastin-rich connective tissue nevi (elastoma) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:elastin-rich connective tissue nevi (elastoma) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:elastosis perforans serpiginosa n1=en:generalized skin thickening (particularly over the trunk) | n2=en:elastosis perforans serpiginosa | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:episodic hyperhidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:episodic hyperhidrosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:erythema in affected areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema in affected areas | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:erythema, blisters, pustules (cyclical, explosive episodes) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema, blisters, pustules (cyclical, explosive episodes) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:excessive bruising and scarring after injuries and scratching n1=en:generalized skin thickening (particularly over the trunk) | n2=en:excessive bruising and scarring after injuries and scratching | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:facial angiofibroma (adenoma sebaceum) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial angiofibroma (adenoma sebaceum) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:facial capillary hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial capillary hemangioma | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:fibrous skin tumor of tuberous sclerosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fibrous skin tumor of tuberous sclerosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:fine whitish scales (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine whitish scales (rare) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:fistula, enterocutaneous n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fistula, enterocutaneous | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:flares of erythema, scaling, and pustules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flares of erythema, scaling, and pustules | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:flexural acanthosis nigricans (females, childhood-early adolescence) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flexural acanthosis nigricans (females, childhood-early adolescence) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:florid red complexion (finding) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:florid red complexion (finding) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:focal skin hypoplasia in face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal skin hypoplasia in face | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:folliculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:folliculitis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:freckles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:freckles | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:frequent bleeding may occur with trauma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:frequent bleeding may occur with trauma | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:generalized epidermolysis (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized epidermolysis (rare) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hemangiomata in at least first branch (ophthalmic) of trigeminal nerve distribution, unilateral, occasionally bilateral n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangiomata in at least first branch (ophthalmic) of trigeminal nerve distribution, unilateral, occasionally bilateral | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperelasticity (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperelasticity (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperkeratosis on dorsal surface of fingers and toes (knuckle pads, in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis on dorsal surface of fingers and toes (knuckle pads, in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperkeratotic plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic plaques | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperkeratotic plaques on trunk and limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic plaques on trunk and limbs | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperpigmentation in sun-exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmentation in sun-exposed areas | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperpigmented erythematous lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented erythematous lesions | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperpigmented lesions, 0.2-0.5 cm n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented lesions, 0.2-0.5 cm | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperpigmented spots on hands (especially palms), arms, feet (especially plantar areas), legs, and lips n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented spots on hands (especially palms), arms, feet (especially plantar areas), legs, and lips | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hyperpigmented whorls n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented whorls | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:hypoplastic flexion creases dorsum of hand n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic flexion creases dorsum of hand | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:ichthyosiform erythroderma sparing the palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosiform erythroderma sparing the palms | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:increased sweating n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased sweating | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:intentional self-injury n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intentional self-injury | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:islands of uninvolved skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:islands of uninvolved skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:itching ( in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:itching ( in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:jaundice, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice, episodic | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:keloid n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keloid | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:keratinocyte n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratinocyte | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:keratosis pilaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis pilaris | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:knee dimple n1=en:generalized skin thickening (particularly over the trunk) | n2=en:knee dimple | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lack of perspiration n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lack of perspiration | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lentigines may be congenital or develop in first months to years of life n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lentigines may be congenital or develop in first months to years of life | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lesions occur on the trunk, back, arms, legs, abdomen, buttocks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions occur on the trunk, back, arms, legs, abdomen, buttocks | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lesions predominantly on face and limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions predominantly on face and limbs | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:leukoplakia (seen in recessive form) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:leukoplakia (seen in recessive form) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lichenoid lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenoid lesions | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:limited dermatologic function n1=en:generalized skin thickening (particularly over the trunk) | n2=en:limited dermatologic function | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:linear atrophic hyperpigmented streak on left index finger n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear atrophic hyperpigmented streak on left index finger | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:linear atrophy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear atrophy | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:lipoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lipoma | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:livedo reticularis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:livedo reticularis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:malar flush n1=en:generalized skin thickening (particularly over the trunk) | n2=en:malar flush | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:mild lamellar ichthyosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild lamellar ichthyosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:molluscoid pseudotumors n1=en:generalized skin thickening (particularly over the trunk) | n2=en:molluscoid pseudotumors | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:moniliasis/candida (excluding x72 y75) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:moniliasis/candida (excluding x72 y75) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:multiple asymptomatic papules with atrophic white scar-like centers surrounded by telangiectatic borders n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple asymptomatic papules with atrophic white scar-like centers surrounded by telangiectatic borders | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:multiple facial papules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple facial papules | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:multiple palmar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple palmar creases | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:nipple dermatitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nipple dermatitis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:no eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no eczema | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:no increased bruisability n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no increased bruisability | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:no systemic vascular lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no systemic vascular lesions | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:no telangiectasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no telangiectasis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:nodular lesion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nodular lesion | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:nonscarring blisters (hand, feet, forearms) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nonscarring blisters (hand, feet, forearms) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:normal sweating capacity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal sweating capacity | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:other dermatologic congenital anomalies n1=en:generalized skin thickening (particularly over the trunk) | n2=en:other dermatologic congenital anomalies | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:palmar creases, fine to acrogeria-like n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar creases, fine to acrogeria-like | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:palmoplantar keratoderma, mild n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar keratoderma, mild | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:papular keratoderma, mild n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papular keratoderma, mild | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:papules, keratotic follicular n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papules, keratotic follicular | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pebbly skin lesions on back, upper arms, and thigh n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pebbly skin lesions on back, upper arms, and thigh | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentation | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pitted, perioral acneiform scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pitted, perioral acneiform scars | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:planar xanthomas (detroit type 107680.0011) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:planar xanthomas (detroit type 107680.0011) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:plantar pits n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar pits | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:plantar softness n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar softness | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pretibial dimples n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pretibial dimples | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:profuse sweating of the upper body induced by cold exposure n1=en:generalized skin thickening (particularly over the trunk) | n2=en:profuse sweating of the upper body induced by cold exposure | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:progressive reticulate hyperpigmentation (axillae, groin, perineal, perianal) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:progressive reticulate hyperpigmentation (axillae, groin, perineal, perianal) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:prominent veins n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent veins | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:prominent veins (especially over scalp and limbs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent veins (especially over scalp and limbs) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:prominent venous pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent venous pattern | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pruritis, intense n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritis, intense | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pterygia of digits, neck, axillae, antecubital, popliteal, intercrural areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygia of digits, neck, axillae, antecubital, popliteal, intercrural areas | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pterygia of elbows (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygia of elbows (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pterygium of axilla (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium of axilla (rare) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:punctate keratitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punctate keratitis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:purple-red skin lesions (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:purple-red skin lesions (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:pustulosis or pustular psoriasis, generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pustulosis or pustular psoriasis, generalized | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:rash (erythematous macules or papules) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash (erythematous macules or papules) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:redness n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redness | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:residual postinflammatory hyperpigmentation, moderate n1=en:generalized skin thickening (particularly over the trunk) | n2=en:residual postinflammatory hyperpigmentation, moderate | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:reticular hyperpigmentation (neck) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticular hyperpigmentation (neck) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:scarring (late complication) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scarring (late complication) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:scarring of blistered skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scarring of blistered skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:sclerodactyly n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sclerodactyly | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:scleroderma-like change n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scleroderma-like change | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:sebaceous cyst n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sebaceous cyst | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:self-healing collodion baby (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:self-healing collodion baby (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:simian crease (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:simian crease (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin blistering, intermittent n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin blistering, intermittent | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin blisters and erosions (neck, perianal, submaxillary, groin, axilla, popliteal fossa) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin blisters and erosions (neck, perianal, submaxillary, groin, axilla, popliteal fossa) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin changes worse in areas of lower skin temperature n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin changes worse in areas of lower skin temperature | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin may redden during episodes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin may redden during episodes | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin of left upper limb n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of left upper limb | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin of trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of trunk | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:skin ulcer n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin ulcer | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:small, red lesion, may increase in size with age n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small, red lesion, may increase in size with age | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:soft velvety skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:soft velvety skin (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:spiky hyperkeratotic lesions on ankles, elbows, and popliteal fossae n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spiky hyperkeratotic lesions on ankles, elbows, and popliteal fossae | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:spotty hypopigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spotty hypopigmentation | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:stage 4 - skin pallor, atrophy, and scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stage 4 - skin pallor, atrophy, and scarring | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:starfish-like acral keratoses (knuckles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:starfish-like acral keratoses (knuckles) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:sterile abscesses at site of parenteral injection n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sterile abscesses at site of parenteral injection | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:stevens-johnson syndrome n1=en:generalized skin thickening (particularly over the trunk) | n2=en:stevens-johnson syndrome | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:subcutaneous ossifications n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous ossifications | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:subcutaneous papules in infancy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous papules in infancy | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sweat glands | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:sweating, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sweating, episodic | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:taunt skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:taunt skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:telangiectasia (soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasia (soles) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:tenderness in areas of eroded skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tenderness in areas of eroded skin (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:tenting - skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tenting - skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:tone does not appreciably change with age n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tone does not appreciably change with age | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:transient pruritic vesicles on trunk, abdomen, and limbs (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transient pruritic vesicles on trunk, abdomen, and limbs (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:transparent skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transparent skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:trichilemmal cyst n1=en:generalized skin thickening (particularly over the trunk) | n2=en:trichilemmal cyst | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:tumors undergo spontaneous resolution over a period of months n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tumors undergo spontaneous resolution over a period of months | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:ulcer n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcer | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:urticaria n1=en:generalized skin thickening (particularly over the trunk) | n2=en:urticaria | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:urticaria pigmentosa or cutaneous mastocytosis (in patients with kit mutations) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:urticaria pigmentosa or cutaneous mastocytosis (in patients with kit mutations) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:usually occurs in the head and neck area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:usually occurs in the head and neck area | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:variable number of lesions (1 to greater than 10) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:variable number of lesions (1 to greater than 10) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:variable skin syndactyly fingers and toes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:variable skin syndactyly fingers and toes | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:vernix-like skin covering, present at birth, shed during first month of life (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vernix-like skin covering, present at birth, shed during first month of life (in some patients) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:vitiligo (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vitiligo (1 patient) | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:warfarin-induced skin necrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:warfarin-induced skin necrosis | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:warts n1=en:generalized skin thickening (particularly over the trunk) | n2=en:warts | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:warty thickening of flexural skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:warty thickening of flexural skin | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:white at birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:white at birth | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:wrinkled soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled soles | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:wrinkling of skin on limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkling of skin on limbs | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 28 / 0.651 -> en:wrinkly skin at birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkly skin at birth | rel=r_associated | relid=0 | w=28 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:abnormal finger flexion creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal finger flexion creases | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:abnormal sweating due to autonomic dysfunction n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal sweating due to autonomic dysfunction | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:absence of all distal creases of second to fifth digits n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of all distal creases of second to fifth digits | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:absence of pretibial myxedema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of pretibial myxedema | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:absence of skin creases over proximal interphalangeal (pip) joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:absence of skin creases over proximal interphalangeal (pip) joints | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:acanthosis nigricans n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:acanthosis nigricans in patients with diabetes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans in patients with diabetes | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:acne conglobata n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acne conglobata | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:acrodermatitis enteropathica, transient, seen in breastfed offspring of affected mothers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acrodermatitis enteropathica, transient, seen in breastfed offspring of affected mothers | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:albinoidism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:albinoidism | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:anhidrosis, patchy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:anhidrosis, patchy | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:aplasia cutis congenita over posterior parietal area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis congenita over posterior parietal area | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:areas of hypopigmentation and hyperpigmentation that do not follow blaschko lines (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:areas of hypopigmentation and hyperpigmentation that do not follow blaschko lines (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:basaloid follicular harmartomas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:basaloid follicular harmartomas | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:breaks in epidermal ridges of palms and fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:breaks in epidermal ridges of palms and fingers | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:brown macules in a reticulate pattern (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:brown macules in a reticulate pattern (rare) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cafe-au-lait spots (93%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe-au-lait spots (93%) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cafe-noir spots (trunk) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe-noir spots (trunk) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:calcinosis cutis metastatica n1=en:generalized skin thickening (particularly over the trunk) | n2=en:calcinosis cutis metastatica | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:capillary hemangioma (forehead) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:capillary hemangioma (forehead) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cicatrization n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cicatrization | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:congenital absence of skin in areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital absence of skin in areas | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cutaneous dimpling over bowed tibia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous dimpling over bowed tibia | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cysts may be multiple (70%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts may be multiple (70%) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cysts may be solitary (30%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts may be solitary (30%) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:cysts may become infected (15%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts may become infected (15%) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dark brown, hard, adherent scales on neck, elbows, and knees n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dark brown, hard, adherent scales on neck, elbows, and knees | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:de- or hypo-pigmented macules (less common) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:de- or hypo-pigmented macules (less common) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:decreased sweating of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:decreased sweating of palms and soles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:deep fissures of skin creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep fissures of skin creases | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:deep plantar creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deep plantar creases | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:deposition of calcium phosphate crystals in skin and subcutaneous tissues n1=en:generalized skin thickening (particularly over the trunk) | n2=en:deposition of calcium phosphate crystals in skin and subcutaneous tissues | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dermal translucency n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermal translucency | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dermis thinning n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermis thinning | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:diffuse hyperkeratosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse hyperkeratosis (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:diffuse skin atrophy (especially dorsa of hands and feet) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse skin atrophy (especially dorsa of hands and feet) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:diffuse telangiectasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:diffuse telangiectasis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dimples (medial and lateral aspect of lower leg) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dimples (medial and lateral aspect of lower leg) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dry skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:dry, rough skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dry, rough skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:easy bruising (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:easy bruising (1 family) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:eczema (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:edema, generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:edema, generalized | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:entire skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:entire skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:eruptive xanthoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eruptive xanthoma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:erythema, cold-induced n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema, cold-induced | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:erythematous affected skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous affected skin (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:erythematous palmoplantar hyperkeratosis, progressive extending onto dorsum of hands and achilles tendon area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous palmoplantar hyperkeratosis, progressive extending onto dorsum of hands and achilles tendon area | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:erythrokeratodermia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythrokeratodermia | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:extrusion of calcium deposits ('perforating pxe') n1=en:generalized skin thickening (particularly over the trunk) | n2=en:extrusion of calcium deposits ('perforating pxe') | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:facial milia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial milia | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:fissures of soles (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fissures of soles (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:flaky skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flaky skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:focal keratoderma of soles (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal keratoderma of soles (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:follicular atrophoderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular atrophoderma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:follicular hyperkeratosis (trunk and limbs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular hyperkeratosis (trunk and limbs) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:follicular keratosis, generalized (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:follicular keratosis, generalized (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:fragile skin with atrophic scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fragile skin with atrophic scarring | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:freckling in a butterfly pattern on the face n1=en:generalized skin thickening (particularly over the trunk) | n2=en:freckling in a butterfly pattern on the face | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:generalized hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized hyperkeratosis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangioma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hemangioma (neck and forehead) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangioma (neck and forehead) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hidrocystoma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hidrocystoma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperalgesia to pressure n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperalgesia to pressure | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperextensible skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperextensible skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperkeratosis of weight-bearing areas of soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis of weight-bearing areas of soles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperkeratotic lesions of neck, elbows, knees, groin, genitalia, and buttocks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic lesions of neck, elbows, knees, groin, genitalia, and buttocks | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperkeratotic porokeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic porokeratosis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperlinearity of palms (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperlinearity of palms (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hypermelanotic macule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypermelanotic macule | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperpigmented streaks n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented streaks | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hyperpigmented streaks following lines of blaschko n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented streaks following lines of blaschko | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hypertrophic scar n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrophic scar | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:hypopigmentation (seen only in deletion cases) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmentation (seen only in deletion cases) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:ichthyosiform areas of skin (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosiform areas of skin (rare) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:ichthyosiform erythroderma, congenital n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosiform erythroderma, congenital | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:ichthyosis (1 family) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis (1 family) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:increased/decreased skin pigment n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased/decreased skin pigment | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:intercrural pterygium n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intercrural pterygium | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:intertrigo n1=en:generalized skin thickening (particularly over the trunk) | n2=en:intertrigo | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keloid formation in surgical scars n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keloid formation in surgical scars | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keratinized, purple, nodular skin lesions (in 2 of 4 patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratinized, purple, nodular skin lesions (in 2 of 4 patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keratoderma (palms and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma (palms and soles) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keratoderma of margins of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma of margins of palms and soles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keratoderma, mutilating, of palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratoderma, mutilating, of palms and soles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:keratotic plaque, periorificial n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratotic plaque, periorificial | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lack of chilblain lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lack of chilblain lesions | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lack of scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lack of scarring | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:large hard compact painful masses of keratin at sites of recurrent friction on palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large hard compact painful masses of keratin at sites of recurrent friction on palms and soles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lesions become purpuric n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions become purpuric | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lesions often follow blaschko lines n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lesions often follow blaschko lines | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:leukoplakia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:leukoplakia | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lichenification of palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenification of palms | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lipoma of skin and subcutaneous tissue of scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lipoma of skin and subcutaneous tissue of scalp | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:localized cutaneous deposits of superficial fat n1=en:generalized skin thickening (particularly over the trunk) | n2=en:localized cutaneous deposits of superficial fat | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:lymphedema (lower limb) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lymphedema (lower limb) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:midface capillary hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:midface capillary hemangioma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:mild localized pigmentation abnormalities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild localized pigmentation abnormalities | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:milium cyst n1=en:generalized skin thickening (particularly over the trunk) | n2=en:milium cyst | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:moderate erythroderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:moderate erythroderma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:mutilating skin deformity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mutilating skin deformity | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:necrosis leading to amputation (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:necrosis leading to amputation (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:neonatal acral blistering n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal acral blistering | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:neonatal blisters and erosions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neonatal blisters and erosions | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:neurofibroma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neurofibroma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:nevus, epidermal (disorder) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus, epidermal (disorder) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:no palmoplantar keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no palmoplantar keratosis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:nonbullous ichthyosiform erythroderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nonbullous ichthyosiform erythroderma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:normal sweating n1=en:generalized skin thickening (particularly over the trunk) | n2=en:normal sweating | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:numbness, pain, and tingling of the fingers in response to cold n1=en:generalized skin thickening (particularly over the trunk) | n2=en:numbness, pain, and tingling of the fingers in response to cold | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:odoriferous,, hypertrophic plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:odoriferous,, hypertrophic plaques | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:overlapping lesion of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:overlapping lesion of skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pallor n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pallor | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pallor (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pallor (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pallor during episodes n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pallor during episodes | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:palmar hyperlinearity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmar hyperlinearity | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:papillomas (perioral, nasal, and anal regions) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomas (perioral, nasal, and anal regions) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:perioral erythema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:perioral erythema | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:plantar keratoderma (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar keratoderma (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:plaque-like facial hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plaque-like facial hemangioma | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:plaques, erythematous, covered with fine powdery scales n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plaques, erythematous, covered with fine powdery scales | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:poikiloderma (atrophic plaques with telangiectasia) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:poikiloderma (atrophic plaques with telangiectasia) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:popliteal pterygium n1=en:generalized skin thickening (particularly over the trunk) | n2=en:popliteal pterygium | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:popliteal webbing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:popliteal webbing | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:porokeratosis of mibelli n1=en:generalized skin thickening (particularly over the trunk) | n2=en:porokeratosis of mibelli | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:primarily affects trunk n1=en:generalized skin thickening (particularly over the trunk) | n2=en:primarily affects trunk | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:proliferating cells show nuclear expression of lymphoid enhancer binding factor-1 (lef1, 153245) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:proliferating cells show nuclear expression of lymphoid enhancer binding factor-1 (lef1, 153245) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:prominent fingerpads (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent fingerpads (rare) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:prominent palmar flexion creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent palmar flexion creases | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pruritis, cold-induced n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritis, cold-induced | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pruritus during pregnancy, resolves postpartum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus during pregnancy, resolves postpartum | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pruritus of scalp n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus of scalp | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pseudoainhum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pseudoainhum | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:psoriasiform keratoses on knees, extensor surfaces of legs, and dorsum of feet (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform keratoses on knees, extensor surfaces of legs, and dorsum of feet (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:psoriasiform plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:psoriasiform plaques | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pterygium n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pterygium of elbow, bilateral (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pterygium of elbow, bilateral (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:punctate vasculitis skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:punctate vasculitis skin lesions | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:pustular rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pustular rash | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:rash, urticarial, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash, urticarial, episodic | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:recurrent cellulitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent cellulitis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:recurrent shingles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent shingles | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:recurrent skin ulcerations (face, trunk, limbs) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:recurrent skin ulcerations (face, trunk, limbs) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:reddish or purplish skin discoloration, episodic, associated with pain n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reddish or purplish skin discoloration, episodic, associated with pain | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:reduced digital creases (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced digital creases (rare) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:reduced distal interphalangeal creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reduced distal interphalangeal creases | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:reticulate hyperpigmentation (primarily trunk) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate hyperpigmentation (primarily trunk) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:reticulate pigmented skin abnormalities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate pigmented skin abnormalities | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:rough, thick palmar skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rough, thick palmar skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:scalding burn n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalding burn | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:scaly skin rash over the perineum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scaly skin rash over the perineum | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:sebaceous gland tumors n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sebaceous gland tumors | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:sebaceous glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sebaceous glands | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:seborrheic keratosis-like papules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:seborrheic keratosis-like papules | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:severe facial acne (in female patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:severe facial acne (in female patient) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:shagreen patch n1=en:generalized skin thickening (particularly over the trunk) | n2=en:shagreen patch | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:single transverse palmar crease (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:single transverse palmar crease (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin absorption n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin absorption | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin appearance normal (finding) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin appearance normal (finding) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin lacks elastic recoil n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin lacks elastic recoil | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin nodules - fingers, elbows, nose, ears (onset infancy-childhood) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin nodules - fingers, elbows, nose, ears (onset infancy-childhood) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin of neck n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of neck | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin of right lower limb n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of right lower limb | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin of right upper limb n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of right upper limb | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin over joint surfaces of hands and feet is thick, red, and edematous n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin over joint surfaces of hands and feet is thick, red, and edematous | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin pigmentation - finding n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin pigmentation - finding | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin structure of head n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin structure of head | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:skin tags on palms (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin tags on palms (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:small conically shaped papules (1 to 3 mm in diameter) located on face, neck, trunk, and limbs n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small conically shaped papules (1 to 3 mm in diameter) located on face, neck, trunk, and limbs | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:spiny follicular plugging n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spiny follicular plugging | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:spotted and reticulate pigmentation of flexural areas of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:spotted and reticulate pigmentation of flexural areas of skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:starfish keratoses (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:starfish keratoses (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:subcutaneous calcification n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous calcification | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:subcutaneous infections, recurrent, with fistula formation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous infections, recurrent, with fistula formation | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:subcutaneous nodule n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous nodule | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:subcutaneous tumors, recurring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:subcutaneous tumors, recurring | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:superficial generalized lifelong skin peeling (sparing palms and soles) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:superficial generalized lifelong skin peeling (sparing palms and soles) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:telangiectasia of photoexposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:telangiectasia of photoexposed areas | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:thickened skin over flexor surface of proximal phalanges n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickened skin over flexor surface of proximal phalanges | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:thickening of skin on the plantar and palmar surfaces n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thickening of skin on the plantar and palmar surfaces | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:transgression of hyperkeratosis to dorsum of hands and feet (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transgression of hyperkeratosis to dorsum of hands and feet (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:transgressive keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transgressive keratosis | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:trichoepitheliomas, multiple (usually occur in the nasolabial folds, nose, or face) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:trichoepitheliomas, multiple (usually occur in the nasolabial folds, nose, or face) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:trichoepitheliomas, multiple (usually occur in thenasolabial folds, the nose, and upper lip) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:trichoepitheliomas, multiple (usually occur in thenasolabial folds, the nose, and upper lip) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:ulcers, plantar n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ulcers, plantar | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:unprovoked bruising n1=en:generalized skin thickening (particularly over the trunk) | n2=en:unprovoked bruising | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:urticaria due to cold n1=en:generalized skin thickening (particularly over the trunk) | n2=en:urticaria due to cold | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:velvety, smooth skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:velvety, smooth skin | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:wound healing normal n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wound healing normal | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:wrinkled forehead at birth (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled forehead at birth (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:wrinkled palms n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled palms | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:wrinkled skin over dorsa of fingers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:wrinkled skin over dorsa of fingers | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 27 / 0.628 -> en:xanthomas (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:xanthomas (in some patients) | rel=r_associated | relid=0 | w=27 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:2. yellowish, flat plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:2. yellowish, flat plaques | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:abnormal scarring n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal scarring | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:abnormal subcutaneous fat tissue distribution n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abnormal subcutaneous fat tissue distribution | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:abscesses (in skin folds that carry terminal hairs and apocrine glands including axillae, groin, anal fold, mons pubis, and scalp, but not face) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:abscesses (in skin folds that carry terminal hairs and apocrine glands including axillae, groin, anal fold, mons pubis, and scalp, but not face) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:acanthosis nigricans (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:acanthosis nigricans (uncommon) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acanthosis nigricans (uncommon) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:acne, severe comedogenic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acne, severe comedogenic | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:acral ulcers n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acral ulcers | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:acrogeria n1=en:generalized skin thickening (particularly over the trunk) | n2=en:acrogeria | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:actinic keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:actinic keratosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:albinism n1=en:generalized skin thickening (particularly over the trunk) | n2=en:albinism | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:aplasia cutis congenita of the abdomen (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis congenita of the abdomen (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:aplasia cutis congenita on skull vertex n1=en:generalized skin thickening (particularly over the trunk) | n2=en:aplasia cutis congenita on skull vertex | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:asymmetric, linear skin defects (anterior face and neck) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:asymmetric, linear skin defects (anterior face and neck) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:asymptomatic soft white spongy mucosal plaques with thick folded surfaces n1=en:generalized skin thickening (particularly over the trunk) | n2=en:asymptomatic soft white spongy mucosal plaques with thick folded surfaces | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:bathing suit distribution of ichthyosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bathing suit distribution of ichthyosis (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:blistering (fingers, toes, pinnae) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering (fingers, toes, pinnae) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:blistering, generalized, neonatal onset n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, generalized, neonatal onset | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:blistering, recurrent, of the palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blistering, recurrent, of the palms and soles | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:blisters in sun-exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:blisters in sun-exposed areas | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:bridge between vertical and transverse proximal palmar flexion creases n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bridge between vertical and transverse proximal palmar flexion creases | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:bruise/contusion intact skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:bruise/contusion intact skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cafe au lait spots on trunk and extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cafe au lait spots on trunk and extremities | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:candidiasis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:candidiasis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:centrofacial/mucosal lentigines n1=en:generalized skin thickening (particularly over the trunk) | n2=en:centrofacial/mucosal lentigines | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:coccygeal skin tags n1=en:generalized skin thickening (particularly over the trunk) | n2=en:coccygeal skin tags | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:congenital palmoplantar keratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:congenital palmoplantar keratosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cutaneous folliculitis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous folliculitis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cutaneous laxity (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutaneous laxity (rare) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cutis laxa, hands and feet (present at birth) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis laxa, hands and feet (present at birth) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cutis marmorata (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cutis marmorata (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:cysts over wrist and ankle joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:cysts over wrist and ankle joints | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:depigmentation/hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:depigmentation/hyperpigmentation | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:dermal contractures (late complication) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermal contractures (late complication) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:dermal melanocytosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dermal melanocytosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:desquamation of skin soon after birth n1=en:generalized skin thickening (particularly over the trunk) | n2=en:desquamation of skin soon after birth | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:dimples over large joints n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dimples over large joints | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:dystrophic epidermolysis bullosa (predominantly but not restricted to the pretibial area) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:dystrophic epidermolysis bullosa (predominantly but not restricted to the pretibial area) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:eczema (in 1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:eczema (in 1 patient) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:epidermal ridges absent from palms and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:epidermal ridges absent from palms and soles | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erysipelas (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erysipelas (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythema marginatum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythema marginatum | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythematous blotching, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous blotching, episodic | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythematous hyperkeratotic plaques on extremities (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous hyperkeratotic plaques on extremities (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythematous ichthyotic skin with reticulate pattern n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous ichthyotic skin with reticulate pattern | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythematous plaque n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythematous plaque | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:erythermalgia (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:erythermalgia (rare) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:facial hemangioma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial hemangioma | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:facial milia, congenital, especially on chin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:facial milia, congenital, especially on chin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:fear of having other skin disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fear of having other skin disease | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:fine whitish scales over entire surface of skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:fine whitish scales over entire surface of skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:flushing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:flushing | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:focal keratoderma of soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:focal keratoderma of soles | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:forehead hyperpigmentation n1=en:generalized skin thickening (particularly over the trunk) | n2=en:forehead hyperpigmentation | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:generalized bronze hyperpigmentation (present at birth) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized bronze hyperpigmentation (present at birth) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hemangiomas (facial, glabellar) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangiomas (facial, glabellar) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hemangiomas and lymphangiomas of any site n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hemangiomas and lymphangiomas of any site | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:histology shows 'cannonball' distribution of capillary-sized vessels in the dermis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:histology shows 'cannonball' distribution of capillary-sized vessels in the dermis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hyperkeratosis palmaris and plantaris n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis palmaris and plantaris | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hyperkeratosis pilaris may occur n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratosis pilaris may occur | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hyperkeratotic papules, dark brown, on neck, chest, and back (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic papules, dark brown, on neck, chest, and back (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hyperkeratotic plaques (face, elbow, knees) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperkeratotic plaques (face, elbow, knees) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hyperpigmented nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hyperpigmented nevi | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hypertrichosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypertrichosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hypohidrosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypohidrosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hypopigmented patches (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypopigmented patches (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:hypoplastic sweat glands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:hypoplastic sweat glands | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:ichthyosis, generalized, including flexures n1=en:generalized skin thickening (particularly over the trunk) | n2=en:ichthyosis, generalized, including flexures | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:impaired healing n1=en:generalized skin thickening (particularly over the trunk) | n2=en:impaired healing | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:increased tendency to bruise n1=en:generalized skin thickening (particularly over the trunk) | n2=en:increased tendency to bruise | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:infected finger/toe/paronychia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:infected finger/toe/paronychia | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:inner zone of enucleated 'shadow' cells n1=en:generalized skin thickening (particularly over the trunk) | n2=en:inner zone of enucleated 'shadow' cells | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:jaundice (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (1 patient) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:jaundice (in some patients), resolved postpartum n1=en:generalized skin thickening (particularly over the trunk) | n2=en:jaundice (in some patients), resolved postpartum | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:keratosis pilaris of trunk and extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:keratosis pilaris of trunk and extremities | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:large diamond-shaped plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:large diamond-shaped plaques | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:larger and darker scales on neck, elbows, and knees (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:larger and darker scales on neck, elbows, and knees (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:leiomyomas are sensitive to light touch n1=en:generalized skin thickening (particularly over the trunk) | n2=en:leiomyomas are sensitive to light touch | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:lichenoid plaques n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lichenoid plaques | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:linear porokeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear porokeratosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:linear porokeratosis (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:linear porokeratosis (1 patient) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:lymphedema (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:lymphedema (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:maculae are homogeneous or telangiectatic and may vary in color from pale pink to red, purple or brown n1=en:generalized skin thickening (particularly over the trunk) | n2=en:maculae are homogeneous or telangiectatic and may vary in color from pale pink to red, purple or brown | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:malar rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:malar rash | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:marbled skin due to telangiectasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:marbled skin due to telangiectasia | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:migratory plaques of thickened, sharply demarcated erythema and hyperkeratosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:migratory plaques of thickened, sharply demarcated erythema and hyperkeratosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:mild tissue fragility n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mild tissue fragility | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:mottled pigmentation of photoexposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mottled pigmentation of photoexposed areas | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:mottled pigmentation of the trunk and proximal extremities n1=en:generalized skin thickening (particularly over the trunk) | n2=en:mottled pigmentation of the trunk and proximal extremities | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:multiple truncal cafe-au-lait spots (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:multiple truncal cafe-au-lait spots (rare) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:myxedema (untreated hypothyroidism) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:myxedema (untreated hypothyroidism) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:neurofibromas, subcutaneous (76%) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:neurofibromas, subcutaneous (76%) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:nevus flammeus simplex on the forehead n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nevus flammeus simplex on the forehead | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:no pruritis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:no pruritis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:nodular skin lesions n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nodular skin lesions | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:nonmelanoma skin cancer (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:nonmelanoma skin cancer (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:numerous nevi n1=en:generalized skin thickening (particularly over the trunk) | n2=en:numerous nevi | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pachyderma n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pachyderma | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:palmoplantar hyperlinearity n1=en:generalized skin thickening (particularly over the trunk) | n2=en:palmoplantar hyperlinearity | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:papillomatosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:papillomatosis over affected area n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papillomatosis over affected area | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:papules enlarge centrifugally to form central atrophic area with an irregular keratotic ridge n1=en:generalized skin thickening (particularly over the trunk) | n2=en:papules enlarge centrifugally to form central atrophic area with an irregular keratotic ridge | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:petechiae n1=en:generalized skin thickening (particularly over the trunk) | n2=en:petechiae | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pigmentary changes on the shins (1 patient) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pigmentary changes on the shins (1 patient) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pilo-sebaceous apparatus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pilo-sebaceous apparatus | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:plantar wart n1=en:generalized skin thickening (particularly over the trunk) | n2=en:plantar wart | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:popliteal pterygium, bilateral n1=en:generalized skin thickening (particularly over the trunk) | n2=en:popliteal pterygium, bilateral | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:prominent superficial blood vessels n1=en:generalized skin thickening (particularly over the trunk) | n2=en:prominent superficial blood vessels | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pruritus n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pruritus in affected areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus in affected areas | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pruritus secondary to liver disease n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus secondary to liver disease | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pruritus, episodic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pruritus, episodic | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:pseudoainhum of fingers, primarily of fifth digit (in most patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:pseudoainhum of fingers, primarily of fifth digit (in most patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:rash may or may not be pruritic n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash may or may not be pruritic | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:rash scaly n1=en:generalized skin thickening (particularly over the trunk) | n2=en:rash scaly | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:raynaud phenomenon (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:raynaud phenomenon (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:red-violet macular atrophy n1=en:generalized skin thickening (particularly over the trunk) | n2=en:red-violet macular atrophy | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:redundant palmar skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant palmar skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:redundant skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:redundant skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:reticulate hyperpigmentation (periocular, perioral, chest, neck, abdomen) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate hyperpigmentation (periocular, perioral, chest, neck, abdomen) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:reticulate ichthyosis (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:reticulate ichthyosis (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:sacral dimple (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sacral dimple (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:scalp dryness n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp dryness | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:scalp structure n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scalp structure | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:scaly skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scaly skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:scleroderma-like secondary cutaneous sclerosis n1=en:generalized skin thickening (particularly over the trunk) | n2=en:scleroderma-like secondary cutaneous sclerosis | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:sebaceous hyperplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sebaceous hyperplasia | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:shallow indolent cutaneous ulcers (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:shallow indolent cutaneous ulcers (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:size variation (1 x 1 to 6 x 4 cm) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:size variation (1 x 1 to 6 x 4 cm) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin appendages (periorbital, face, thorax, rarely on trunk) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin appendages (periorbital, face, thorax, rarely on trunk) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin erosion n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin erosion | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin hyperlaxity (males) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin hyperlaxity (males) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin hypertrophy, particularly in flexural areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin hypertrophy, particularly in flexural areas | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin of left lower limb n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of left lower limb | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin of lip n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin of lip | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin retraction n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin retraction | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:skin ulcerations (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:skin ulcerations (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:small hemorrhagic blisters on hands n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small hemorrhagic blisters on hands | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:small, annular, anhidrotic keratotic lesions located predominantly on sun-exposed areas n1=en:generalized skin thickening (particularly over the trunk) | n2=en:small, annular, anhidrotic keratotic lesions located predominantly on sun-exposed areas | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:suppurative scalp nodules n1=en:generalized skin thickening (particularly over the trunk) | n2=en:suppurative scalp nodules | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:sweat pore aplasia n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sweat pore aplasia | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:thick facial skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thick facial skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:thin translucent skin (in some patients) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:thin translucent skin (in some patients) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:transient eczema n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transient eczema | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:transient erysipelas-like erythematous rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transient erysipelas-like erythematous rash | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:transplanted skin n1=en:generalized skin thickening (particularly over the trunk) | n2=en:transplanted skin | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:trichoepithelioma (brown, flat-topped papules) (rare) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:trichoepithelioma (brown, flat-topped papules) (rare) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:tumors are locally invasive n1=en:generalized skin thickening (particularly over the trunk) | n2=en:tumors are locally invasive | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:vasculitis rash n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vasculitis rash | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:vesicles, congenital, on fingers and soles n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vesicles, congenital, on fingers and soles | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> en:vesicular lesions (inflammatory type b) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:vesicular lesions (inflammatory type b) | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 26 / 0.605 -> peau n1=en:generalized skin thickening (particularly over the trunk) | n2=peau | rel=r_associated | relid=0 | w=26 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 25 / 0.581 -> en:generalized n1=en:generalized skin thickening (particularly over the trunk) | n2=en:generalized | rel=r_associated | relid=0 | w=25 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 20 / 0.465 -> acanthosis n1=en:generalized skin thickening (particularly over the trunk) | n2=acanthosis | rel=r_associated | relid=0 | w=20 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 20 / 0.465 -> en:annular plaque n1=en:generalized skin thickening (particularly over the trunk) | n2=en:annular plaque | rel=r_associated | relid=0 | w=20 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 20 / 0.465 -> en:sacral dimple (mks) n1=en:generalized skin thickening (particularly over the trunk) | n2=en:sacral dimple (mks) | rel=r_associated | relid=0 | w=20 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 20 / 0.465 -> hyperacanthose n1=en:generalized skin thickening (particularly over the trunk) | n2=hyperacanthose | rel=r_associated | relid=0 | w=20 en:generalized skin thickening (particularly over the trunk) -- r_associated #0: 20 / 0.465 -> oedème n1=en:generalized skin thickening (particularly over the trunk) | n2=oedème | rel=r_associated | relid=0 | w=20

≈ 1820 relations entrantes en:acanthosis --- r_associated #0: 50 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=50 acanthosis --- r_associated #0: 47 --> en:generalized skin thickening (particularly over the trunk) n1=acanthosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=47 en:generalized dry skin with fine scaling and sparing of face (in some patients) --- r_associated #0: 43 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized dry skin with fine scaling and sparing of face (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=43 en:pseudoainhum of fingers, primarily of fifth digit (in most patients) --- r_associated #0: 43 --> en:generalized skin thickening (particularly over the trunk) n1=en:pseudoainhum of fingers, primarily of fifth digit (in most patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=43 en:sensitive skin --- r_associated #0: 43 --> en:generalized skin thickening (particularly over the trunk) n1=en:sensitive skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=43 hyperacanthose --- r_associated #0: 41 --> en:generalized skin thickening (particularly over the trunk) n1=hyperacanthose | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=41 œdème --- r_associated #0: 40 --> en:generalized skin thickening (particularly over the trunk) n1=œdème | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=40 oedème --- r_associated #0: 40 --> en:generalized skin thickening (particularly over the trunk) n1=oedème | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=40 œdème --- r_associated #0: 40 --> en:generalized skin thickening (particularly over the trunk) n1=œdème | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=40 en:bald area on scalp (in some patients) --- r_associated #0: 35 --> en:generalized skin thickening (particularly over the trunk) n1=en:bald area on scalp (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=35 en:linear porokeratosis (rare) --- r_associated #0: 35 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear porokeratosis (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=35 en:linear skin defects on face and neck (in both patients) --- r_associated #0: 35 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear skin defects on face and neck (in both patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=35 en:patchy desquamation --- r_associated #0: 35 --> en:generalized skin thickening (particularly over the trunk) n1=en:patchy desquamation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=35 en:reduced distal interphalangeal creases --- r_associated #0: 35 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced distal interphalangeal creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=35 en:focal keratoderma of soles --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal keratoderma of soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:lichenoid lesions --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenoid lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:no telangiectasis --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:no telangiectasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:painless, ulcerating lesions of distal extremities, tongue, and lips --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:painless, ulcerating lesions of distal extremities, tongue, and lips | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:prominent knuckle pads (in some patients) --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent knuckle pads (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:skin atrophy, diffuse, in older patients --- r_associated #0: 34 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin atrophy, diffuse, in older patients | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=34 en:focal hyperkeratosis of dorsum of hands and feet --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal hyperkeratosis of dorsum of hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:recurrent infections due to painless trauma and ulceration --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent infections due to painless trauma and ulceration | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:scalp defect (aplasia cutis congenita) --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp defect (aplasia cutis congenita) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:tenderness in areas of eroded skin (in some patients) --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:tenderness in areas of eroded skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:thin translucent skin with prominent venous patterning --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin translucent skin with prominent venous patterning | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:verrucous proliferation (in some patients) --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:verrucous proliferation (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:woolly hair nevus (in some patients) --- r_associated #0: 32 --> en:generalized skin thickening (particularly over the trunk) n1=en:woolly hair nevus (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=32 en:abnormally pigmented macules --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormally pigmented macules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:hyperkeratosis in the area of joints --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis in the area of joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:lymphedema (in some patients) --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:lymphedema (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:progressive cutaneous atrophy --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:progressive cutaneous atrophy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:psoriasiform keratoses on knees, extensor surfaces of legs, and dorsum of feet (in some patients) --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform keratoses on knees, extensor surfaces of legs, and dorsum of feet (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:psoriasis (rare) --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasis (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:pustular psoriasis (in some patients) --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:pustular psoriasis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:sunburn after short exposure to sun --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:sunburn after short exposure to sun | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:widespread keratinized plaques (in some patients) --- r_associated #0: 31 --> en:generalized skin thickening (particularly over the trunk) n1=en:widespread keratinized plaques (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=31 en:aplasia cutis congenita of the abdomen (in some patients) --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis congenita of the abdomen (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:dystrophic epidermolysis bullosa (predominantly but not restricted to the pretibial area) --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:dystrophic epidermolysis bullosa (predominantly but not restricted to the pretibial area) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:edema --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:edema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:excessive bruising and scarring after injuries and scratching --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:excessive bruising and scarring after injuries and scratching | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:follicular keratosis on elbows and knees --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular keratosis on elbows and knees | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:less pressure required to lift skin --- r_associated #0: 30 --> en:generalized skin thickening (particularly over the trunk) n1=en:less pressure required to lift skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=30 en:antecubital webbing (in some patients) --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:antecubital webbing (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:decreased sweating (1 patient) --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased sweating (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:irregular annular keratotic lesions with slightly elevated borders, located primarily on the face but also distributed on the chest and forearms --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:irregular annular keratotic lesions with slightly elevated borders, located primarily on the face but also distributed on the chest and forearms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:lymphedema (lower limb) --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:lymphedema (lower limb) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:palmoplantar keratoderma, with honeycomb pattern (in most patients) --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, with honeycomb pattern (in most patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:porokeratoma --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:porokeratoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:reduced digital creases (rare) --- r_associated #0: 29 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced digital creases (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=29 en:atrophic hyperpigmented streaks on face and neck --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic hyperpigmented streaks on face and neck | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:deep palmar creases (in some patients) --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep palmar creases (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:erosions, congenital, on dorsal and/or plantar surface of hands and feet --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:erosions, congenital, on dorsal and/or plantar surface of hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:erythroderma, moderate to severe --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythroderma, moderate to severe | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:hyperkeratotic porokeratosis --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic porokeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:multiple truncal cafe-au-lait spots (rare) --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple truncal cafe-au-lait spots (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:popliteal webbing --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:popliteal webbing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:transgradient palmoplantar keratoderma on dorsal hands and feet --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:transgradient palmoplantar keratoderma on dorsal hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:transgredient extension of hyperkeratosis onto wrists (in some patients) --- r_associated #0: 28 --> en:generalized skin thickening (particularly over the trunk) n1=en:transgredient extension of hyperkeratosis onto wrists (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=28 en:circumferential skin creases on neck (in some patients) --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:circumferential skin creases on neck (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:doughy skin (in some patients) --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:doughy skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:flaky skin --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:flaky skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:hypopigmentation of surgical scars --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmentation of surgical scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:ichthyosiform erythroderma sparing the palms --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosiform erythroderma sparing the palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:purple-red skin lesions (in some patients) --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:purple-red skin lesions (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:redundant skin folds on upper and lower limbs --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant skin folds on upper and lower limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:transient pruritic vesicles on trunk, abdomen, and limbs (in some patients) --- r_associated #0: 27 --> en:generalized skin thickening (particularly over the trunk) n1=en:transient pruritic vesicles on trunk, abdomen, and limbs (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=27 en:annular plaque --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:annular plaque | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:hair may not be present on the nevus --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:hair may not be present on the nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:hyperkeratotic papules in blistered areas --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic papules in blistered areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:pigmentary abnormalities along the lines of blaschko --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentary abnormalities along the lines of blaschko | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:pterygium of elbow (rare) --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium of elbow (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:sacral dimple (mks) --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:sacral dimple (mks) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 en:scarring of blistered skin --- r_associated #0: 26 --> en:generalized skin thickening (particularly over the trunk) n1=en:scarring of blistered skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=26 acanthose --- r_associated #0: 24 --> en:generalized skin thickening (particularly over the trunk) n1=acanthose | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=24 Oedème --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=Oedème | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:'ice-pick marks' --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:'ice-pick marks' | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:'orange peel' skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:'orange peel' skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:'orange peel' skin (large pores) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:'orange peel' skin (large pores) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:1-5mm dark lentigines (especially neck and trunk) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:1-5mm dark lentigines (especially neck and trunk) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:1. yellowish, flat papules (neck, antecubital and popliteal fossae, axillae, inguinal, and periumbilical areas) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:1. yellowish, flat papules (neck, antecubital and popliteal fossae, axillae, inguinal, and periumbilical areas) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:2. yellowish, flat plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:2. yellowish, flat plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:3. lax, wrinkled skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:3. lax, wrinkled skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aberrant melanosome maturation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aberrant melanosome maturation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aberrant skin dimples (elbows and knees) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aberrant skin dimples (elbows and knees) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal alignment of collagen bundles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal alignment of collagen bundles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal blistering of the skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal blistering of the skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal dermatoglyphic pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal dermatoglyphic pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal finger flexion creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal finger flexion creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal granulation tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal granulation tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal sensitivity to uvb wavelengths by radiation monochromator skin testing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal sensitivity to uvb wavelengths by radiation monochromator skin testing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal subcutaneous fat tissue distribution --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal subcutaneous fat tissue distribution | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abnormal sweating due to autonomic dysfunction --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abnormal sweating due to autonomic dysfunction | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abrasion/scratch/blister --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abrasion/scratch/blister | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abscess formation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abscess formation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abscess of skin and/or subcutaneous tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abscess of skin and/or subcutaneous tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:abscesses (in skin folds that carry terminal hairs and apocrine glands including axillae, groin, anal fold, mons pubis, and scalp, but not face) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:abscesses (in skin folds that carry terminal hairs and apocrine glands including axillae, groin, anal fold, mons pubis, and scalp, but not face) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of all distal creases of second to fifth digits --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of all distal creases of second to fifth digits | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of dermopathy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of dermopathy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of interphalangeal creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of interphalangeal creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of normal rete ridge pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of normal rete ridge pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of pretibial myxedema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of pretibial myxedema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of skin creases over distal interphalangeal (dip) joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of skin creases over distal interphalangeal (dip) joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of skin creases over proximal interphalangeal (pip) joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of skin creases over proximal interphalangeal (pip) joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absence of subcutaneous fat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absence of subcutaneous fat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent axonal flare response after intradermal histamine injection --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent axonal flare response after intradermal histamine injection | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent dermal ridges --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent dermal ridges | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent distal interphalangeal creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent distal interphalangeal creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent dorsal skin creases over affected joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent dorsal skin creases over affected joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent fingerprints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent fingerprints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent phalangeal crease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent phalangeal crease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent skin pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent skin pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:absent-mild skin hyperextensibility --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:absent-mild skin hyperextensibility | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans (neck, axilla, groin, periorbital region, perioral region) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans (neck, axilla, groin, periorbital region, perioral region) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans (uncommon) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans (uncommon) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans in patients with diabetes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans in patients with diabetes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acanthosis nigricans, axillary (in male patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acanthosis nigricans, axillary (in male patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:accumulation of melanosomes in melanocytes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:accumulation of melanosomes in melanocytes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acne --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acne | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acne conglobata --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acne conglobata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acne inverse (predominantly affecting armpit, groin, inner thigh, perianal and perineal, submammary, and buttock regions) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acne inverse (predominantly affecting armpit, groin, inner thigh, perianal and perineal, submammary, and buttock regions) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acne, severe comedogenic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acne, severe comedogenic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acneform facial lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acneform facial lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acneiform lesions (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acneiform lesions (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acral keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acral keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acral punctate keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acral punctate keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acral ulcers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acral ulcers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acral violaceous plaques and nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acral violaceous plaques and nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acrocyanosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acrocyanosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acrocyanosis of the feet (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acrocyanosis of the feet (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acrodermatitis enteropathica, transient, seen in breastfed offspring of affected mothers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acrodermatitis enteropathica, transient, seen in breastfed offspring of affected mothers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acrogeria --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acrogeria | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:acrokeratosis verruciformis-like lesions on dorsum of hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:acrokeratosis verruciformis-like lesions on dorsum of hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:actinic keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:actinic keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:affects distal limb and scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:affects distal limb and scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:affects limbs and trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:affects limbs and trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:albinism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:albinism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:albinoidism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:albinoidism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:albopapuloid lesions may occur --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:albopapuloid lesions may occur | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:angiokeratoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:angiokeratoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:angiokeratoma corporis diffusum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:angiokeratoma corporis diffusum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:angiokeratomas (soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:angiokeratomas (soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:angioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:angioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:angiomatous lesions on the fingers, persistent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:angiomatous lesions on the fingers, persistent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis (in patients with hsan2d) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis (in patients with hsan2d) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis of the trunk and limbs 100% of the time --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis of the trunk and limbs 100% of the time | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis over skin lesions (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis over skin lesions (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis, patchy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis, patchy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhidrosis, patchy, in some patients --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhidrosis, patchy, in some patients | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:anhydrotic ectodermal dysplasias --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:anhydrotic ectodermal dysplasias | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:animal/human bite --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:animal/human bite | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:annular erythematous edematous plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:annular erythematous edematous plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:annular lesions (3 mm to 1 cm in diameter) located on the face, neck, trunk and limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:annular lesions (3 mm to 1 cm in diameter) located on the face, neck, trunk and limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:antecubial webbing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:antecubial webbing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia cutis congenita --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis congenita | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia cutis congenita on skull vertex --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis congenita on skull vertex | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia cutis congenita on trunk or limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis congenita on trunk or limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia cutis congenita over posterior parietal area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis congenita over posterior parietal area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia cutis of the scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia cutis of the scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia of the sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia of the sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:aplasia/hypoplastia of the eccrine sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:aplasia/hypoplastia of the eccrine sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:arborescent papillomas (axillae, periumbilical area, anus, vulva) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:arborescent papillomas (axillae, periumbilical area, anus, vulva) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:areas of hypopigmentation and hyperpigmentation that do not follow blaschko lines (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:areas of hypopigmentation and hyperpigmentation that do not follow blaschko lines (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:asymmetric, linear skin defects (anterior face and neck) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:asymmetric, linear skin defects (anterior face and neck) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:asymptomatic soft white spongy mucosal plaques with thick folded surfaces --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:asymptomatic soft white spongy mucosal plaques with thick folded surfaces | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atopic dermatitis/eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atopic dermatitis/eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atopy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atopy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic condition of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic condition of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic scar --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic scar | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic scarring (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic scarring (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic scarring (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic scarring (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic scarring, severe --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic scarring, severe | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atrophic skin over ears --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atrophic skin over ears | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atypical nevi (>5mm with irregular edge and pigmentation) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atypical nevi (>5mm with irregular edge and pigmentation) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:atypical nevi often present in non-sun exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:atypical nevi often present in non-sun exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:autoamputation of digits --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:autoamputation of digits | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:autoamputation of fifth toe, bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:autoamputation of fifth toe, bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:axillary apocrine gland hypoplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:axillary apocrine gland hypoplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:axillary freckling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:axillary freckling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:axillary pterygia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:axillary pterygia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:axillary pterygium, bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:axillary pterygium, bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:baldness/losing hair --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:baldness/losing hair | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:basal cell carcinoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:basal cell carcinoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:basal cell layer contains clumped keratin filaments --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:basal cell layer contains clumped keratin filaments | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:basal cell nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:basal cell nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:basaloid follicular harmartomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:basaloid follicular harmartomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bathing suit distribution of ichthyosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bathing suit distribution of ichthyosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bilateral palmar simian creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bilateral palmar simian creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bilateral single palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bilateral single palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bilateral single transverse palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bilateral single transverse palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bilateral transverse palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bilateral transverse palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blanching of the fingers in response to cold --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blanching of the fingers in response to cold | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering (fingers, toes, pinnae) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering (fingers, toes, pinnae) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering at acral sites --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering at acral sites | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering erythematous rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering erythematous rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering may be generalized or localized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering may be generalized or localized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering occurs in clusters ('herpetiform', 'arcuate') --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering occurs in clusters ('herpetiform', 'arcuate') | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering of hands, elbows, feet, knees --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering of hands, elbows, feet, knees | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering of palms in hot weather (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering of palms in hot weather (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering skin lesions, recurrent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering skin lesions, recurrent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, generalized, neonatal onset --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, generalized, neonatal onset | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, generalized, recurrent (occurs after mild physical trauma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, generalized, recurrent (occurs after mild physical trauma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, generalized, recurrent, severe (occurs after mild physical trauma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, generalized, recurrent, severe (occurs after mild physical trauma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, mild (occurs mainly on ankles and feet and in response to trauma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, mild (occurs mainly on ankles and feet and in response to trauma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, recurrent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, recurrent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blistering, recurrent, of the palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blistering, recurrent, of the palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blisters and erosions after mechanical manipulation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blisters and erosions after mechanical manipulation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blisters in sun-exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blisters in sun-exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blood vessel structure of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blood vessel structure of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:blotching pigmentation of the skin (in older children) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:blotching pigmentation of the skin (in older children) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bluish skin nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bluish skin nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bluish-red border demarcating transition to normal skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bluish-red border demarcating transition to normal skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:breaks in epidermal ridges of palms and fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:breaks in epidermal ridges of palms and fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bridge between vertical and transverse proximal palmar flexion creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bridge between vertical and transverse proximal palmar flexion creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bright copper-red coloration of skin (in darker-skinned individuals) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bright copper-red coloration of skin (in darker-skinned individuals) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:brown macules in a reticulate pattern (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:brown macules in a reticulate pattern (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:brown, warty keratotic papules (trunk, scalp, forehead, flexural areas) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:brown, warty keratotic papules (trunk, scalp, forehead, flexural areas) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:brownish macular and lentiginous lesions, disseminated, present on extremities, trunk, and neck --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:brownish macular and lentiginous lesions, disseminated, present on extremities, trunk, and neck | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:brownish-black macules on dorsa of hands and feet (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:brownish-black macules on dorsa of hands and feet (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bruise/contusion intact skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bruise/contusion intact skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bulla --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bulla | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:bullous, pustular dermatitis of extremities, oral, anal, and genital areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:bullous, pustular dermatitis of extremities, oral, anal, and genital areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:burnett schwartz berberian syndrome --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:burnett schwartz berberian syndrome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:burning sensation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:burning sensation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe au lait spot --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe au lait spot | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe au lait spots (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe au lait spots (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe au lait spots on trunk and extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe au lait spots on trunk and extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe au lait spots, multiple --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe au lait spots, multiple | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe-au-lait spot (in 1/4 patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe-au-lait spot (in 1/4 patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe-au-lait spots (93%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe-au-lait spots (93%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe-au-lait spots may or may not be present --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe-au-lait spots may or may not be present | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe-au-lait spots on chest and abdomen (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe-au-lait spots on chest and abdomen (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cafe-noir spots (trunk) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cafe-noir spots (trunk) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:calcification may occur --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:calcification may occur | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:calcified, ulcerating nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:calcified, ulcerating nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:calcinosis cutis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:calcinosis cutis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:calcinosis cutis metastatica --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:calcinosis cutis metastatica | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:calluses on weight-bearing areas of soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:calluses on weight-bearing areas of soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:candida diaper dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:candida diaper dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:candidiasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:candidiasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:candidiasis, chronic mucocutaneous --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:candidiasis, chronic mucocutaneous | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:capillary hemangioma (forehead) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:capillary hemangioma (forehead) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:capillary hemangioma (in 1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:capillary hemangioma (in 1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:capillary malformations, commonly on face or neck, rarely on mucosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:capillary malformations, commonly on face or neck, rarely on mucosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:capillary malformations, small, multiple, diffuse --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:capillary malformations, small, multiple, diffuse | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:carbuncle/furuncle --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:carbuncle/furuncle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cellulitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cellulitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cellulitis over affected area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cellulitis over affected area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cellulitis, recurrent (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cellulitis, recurrent (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:central atrophic area with peripheral keratotic ridge --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:central atrophic area with peripheral keratotic ridge | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:centrofacial/mucosal lentigines --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:centrofacial/mucosal lentigines | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cerebriform connective tissue nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cerebriform connective tissue nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chilblains --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chilblains | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chin dimples --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chin dimples | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chronic candidiasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chronic candidiasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chronic eczematoid rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chronic eczematoid rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chronic folliculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chronic folliculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chronic granulomatous nodules (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chronic granulomatous nodules (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:chronic skin ulcer --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:chronic skin ulcer | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cicatrization --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cicatrization | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cigarette-paper scars --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cigarette-paper scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:circumferential skin creases on extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:circumferential skin creases on extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:circumscribed transparent membrane on the scalp vertex may be ulcerated (other areas of the body are rarely involved) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:circumscribed transparent membrane on the scalp vertex may be ulcerated (other areas of the body are rarely involved) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:clavus formation (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:clavus formation (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:clear gelatinous pterygia-like plaques of the nasal and temporal perilimbal bulbar conjunctiva --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:clear gelatinous pterygia-like plaques of the nasal and temporal perilimbal bulbar conjunctiva | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cleavage within basal keratinocytes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cleavage within basal keratinocytes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:coarse skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:coarse skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:coarse, thick skin (especially upper face and scalp) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:coarse, thick skin (especially upper face and scalp) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:coccygeal skin tags --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:coccygeal skin tags | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collagen-rich connective tissue nevi (dermatofibrosis lenticularis disseminata) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collagen-rich connective tissue nevi (dermatofibrosis lenticularis disseminata) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion membrane at birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion membrane at birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion membrane at birth (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion membrane at birth (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion membrane at birth (in most patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion membrane at birth (in most patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion membrane at birth (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion membrane at birth (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion membrane, self-healing (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion membrane, self-healing (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:collodion skin changes ichthyosis pigmentary abnormalities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:collodion skin changes ichthyosis pigmentary abnormalities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:comedo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:comedo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:common wart --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:common wart | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:confetti-like hypopigmented macules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:confetti-like hypopigmented macules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital absence of skin in areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital absence of skin in areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital absence of skin in some areas (aplasia cutis) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital absence of skin in some areas (aplasia cutis) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital absence of skin on some areas (aplasia cutis) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital absence of skin on some areas (aplasia cutis) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital erythrokeratodermia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital erythrokeratodermia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital ichthyosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital ichthyosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital localized absence of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital localized absence of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital nonbullous ichthyosiform erythroderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital nonbullous ichthyosiform erythroderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital palmoplantar keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital palmoplantar keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital poikiloderma on face and exposed skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital poikiloderma on face and exposed skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:congenital symmetrical palmoplantar keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:congenital symmetrical palmoplantar keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:connective tissue dysplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:connective tissue dysplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:connective tissue nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:connective tissue nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:contact dermatitis and other eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:contact dermatitis and other eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:corns and callus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:corns and callus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:creamy white skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:creamy white skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:crouzon syndrome with acanthosis nigricans (disorder) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:crouzon syndrome with acanthosis nigricans (disorder) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:crusting erythematous dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:crusting erythematous dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous 0.5 to 1.0 cm bluish and flesh-colored papules (rarely reported) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous 0.5 to 1.0 cm bluish and flesh-colored papules (rarely reported) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous albinism, tyrosinase-positive --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous albinism, tyrosinase-positive | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous and mucosal skin tags --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous and mucosal skin tags | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous candidiasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous candidiasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous capillary malformation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous capillary malformation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous dimples (knees, elbows, shoulders) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous dimples (knees, elbows, shoulders) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous dimpling over bowed tibia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous dimpling over bowed tibia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous folliculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous folliculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous hyperpigmentation (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous hyperpigmentation (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous infections (staphylococcus aureus, herpes simplex) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous infections (staphylococcus aureus, herpes simplex) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous laxity (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous laxity (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous leiomyomata (heterozygote carriers) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous leiomyomata (heterozygote carriers) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous leiomyosarcoma (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous leiomyosarcoma (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous lichen amyloidosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous lichen amyloidosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous mastocytosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous mastocytosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous melanoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous melanoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous nevi flammei (limbs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous nevi flammei (limbs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous piloleiomyomas (may be single or multiple) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous piloleiomyomas (may be single or multiple) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous syndactyly --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous syndactyly | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous syndactyly (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous syndactyly (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous telangiectases of face, upper chest, upper mid-back, upper extremities, and hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous telangiectases of face, upper chest, upper mid-back, upper extremities, and hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous vascular malformation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous vascular malformation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutaneous vasculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutaneous vasculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis aplasia, occipital --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis aplasia, occipital | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis gyrata --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis gyrata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis laxa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis laxa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis laxa (especially hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis laxa (especially hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis laxa (infancy) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis laxa (infancy) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis laxa, hands and feet (present at birth) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis laxa, hands and feet (present at birth) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata (45%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata (45%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata (in some) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata (in some) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cutis marmorata telangiectatica congenita --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cutis marmorata telangiectatica congenita | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis (25%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis (25%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis due to congenital heart defect --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis due to congenital heart defect | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis due to methemoglobinemia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis due to methemoglobinemia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis due to respiratory insufficiency --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis due to respiratory insufficiency | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyanosis during episodes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyanosis during episodes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cylindromas usually occur on the scalp may coalesce into large 'turban tumors' --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cylindromas usually occur on the scalp may coalesce into large 'turban tumors' | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cylindromas, multiple (face, trunk and extremities) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cylindromas, multiple (face, trunk and extremities) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cylindromas, multiple (usually occur on the scalp, but may also occur on the face, trunk, and extremities) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cylindromas, multiple (usually occur on the scalp, but may also occur on the face, trunk, and extremities) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyst occur most often on the scalp (89%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyst occur most often on the scalp (89%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cyst of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cyst of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts are firm and smooth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts are firm and smooth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts may be multiple (70%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts may be multiple (70%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts may be solitary (30%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts may be solitary (30%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts may become infected (15%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts may become infected (15%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts may disappear on their own (10%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts may disappear on their own (10%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts may gradually increase in size --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts may gradually increase in size | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts occur less commonly on any part of the body where hair grows --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts occur less commonly on any part of the body where hair grows | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:cysts over wrist and ankle joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:cysts over wrist and ankle joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dark brown, hard, adherent scales on neck, elbows, and knees --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dark brown, hard, adherent scales on neck, elbows, and knees | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dark pigmentation of knees and dorsum of hands and feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dark pigmentation of knees and dorsum of hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dark skin pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dark skin pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:darkening of periorificial areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:darkening of periorificial areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:darkly pigmented skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:darkly pigmented skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:de- or hypo-pigmented macules (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:de- or hypo-pigmented macules (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased flexion creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased flexion creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased histidase activity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased histidase activity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased intraepithelial nerve fiber density --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased intraepithelial nerve fiber density | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased number of sweat pores --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased number of sweat pores | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased skin stiffness --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased skin stiffness | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased sweating due to autonomic dysfunction --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased sweating due to autonomic dysfunction | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased sweating of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased sweating of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased urocanic acid in stratum corneum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased urocanic acid in stratum corneum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:decreased viscoelasticity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:decreased viscoelasticity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep fissures of skin creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep fissures of skin creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep foot creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep foot creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep palmar crease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep palmar crease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep plantar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep plantar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep skin creases in toes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep skin creases in toes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deep skin ulcers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deep skin ulcers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:degeneration of basal epidermal cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:degeneration of basal epidermal cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dependent acrocyanosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dependent acrocyanosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:depigmentation/hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:depigmentation/hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:depigmented spots --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:depigmented spots | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:deposition of calcium phosphate crystals in skin and subcutaneous tissues --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:deposition of calcium phosphate crystals in skin and subcutaneous tissues | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:derived from hair matrix cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:derived from hair matrix cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermal contractures (late complication) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermal contractures (late complication) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermal melanocytosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermal melanocytosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermal ossification (osteoma cutis) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermal ossification (osteoma cutis) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermal translucency --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermal translucency | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis (chronic or chronically relapsing, major feature) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis (chronic or chronically relapsing, major feature) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis acidemica --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis acidemica | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis herpetiformis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis herpetiformis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis ichthyosiform --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis ichthyosiform | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis, atopic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis, atopic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis, infectious, due to immunodeficiency --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis, infectious, due to immunodeficiency | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis, infectious, due to immunodeficiency impetigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis, infectious, due to immunodeficiency impetigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatitis, symmetric pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatitis, symmetric pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatographism (dermatographic urticaria) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatographism (dermatographic urticaria) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatomycoses --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatomycoses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatophytosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatophytosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermatophytosis, chronic deep dermatophytosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermatophytosis, chronic deep dermatophytosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermis thinning --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermis thinning | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dermo-epidermal junction --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dermo-epidermal junction | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:desquamation of skin soon after birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:desquamation of skin soon after birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diaper rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diaper rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diaphoresis (with pheochromocytoma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diaphoresis (with pheochromocytoma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:difficulty grasping or holding objects --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:difficulty grasping or holding objects | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse erythematous maculopapular rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse erythematous maculopapular rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse hyperkeratosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse hyperkeratosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse pigmentary skin mottling, mild, on trunk and proximal limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse pigmentary skin mottling, mild, on trunk and proximal limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse skin atrophy (especially dorsa of hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse skin atrophy (especially dorsa of hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse skin wrinkling (especially dorsa of hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse skin wrinkling (especially dorsa of hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse telangiectasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse telangiectasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diffuse yellow-orange non-epidermolytic hyperkeratosis on palms and soles (palmoplantar keratoderma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diffuse yellow-orange non-epidermolytic hyperkeratosis on palms and soles (palmoplantar keratoderma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dilated scalp veins radiating from periphery of scalp defect --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dilated scalp veins radiating from periphery of scalp defect | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:diminished sweating --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:diminished sweating | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dimple overlying knee --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dimple overlying knee | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dimples (chin, buttocks) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dimples (chin, buttocks) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dimples (medial and lateral aspect of lower leg) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dimples (medial and lateral aspect of lower leg) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dimples (over bowed limbs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dimples (over bowed limbs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dimples over large joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dimples over large joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:discoid lupus in carriers or adults with mild disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:discoid lupus in carriers or adults with mild disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:discoid rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:discoid rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:discrete 2 to 5-mm hyper- and hypopigmented macules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:discrete 2 to 5-mm hyper- and hypopigmented macules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:distal painless ulcers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:distal painless ulcers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:distinct odor of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:distinct odor of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:distorted triradii of palmar skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:distorted triradii of palmar skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dorsal hand wrinkling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dorsal hand wrinkling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:doughy or puffy skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:doughy or puffy skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:doughy skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:doughy skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:draining sinuses (late complication) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:draining sinuses (late complication) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry palmar skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry palmar skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry, bumpy skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry, bumpy skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry, rough skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry, rough skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry, scaly skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry, scaly skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry, stiff skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry, stiff skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dry, thick skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dry, thick skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dyshidrosis [pompholyx] --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dyshidrosis [pompholyx] | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dysseborrheic dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dysseborrheic dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:dystrophic scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:dystrophic scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:early freckle-like lesions in exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:early freckle-like lesions in exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:early onset skin cancer (basal cell, squamous cell and malignant melanoma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:early onset skin cancer (basal cell, squamous cell and malignant melanoma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:easier stretching --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:easier stretching | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:easy bruising (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:easy bruising (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:easy bruising (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:easy bruising (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ecchymoses common --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ecchymoses common | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ecchymoses, congenital (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ecchymoses, congenital (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ecchymosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ecchymosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eccrine poroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eccrine poroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ectodermal dysplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ectodermal dysplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ectodermal dystrophy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ectodermal dystrophy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ectodermal symptoms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ectodermal symptoms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (8 of 23) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (8 of 23) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (face and flexural areas) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (face and flexural areas) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (in 1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (in 1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (in rare mutation carriers unaffected by a hematologic malignancy) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (in rare mutation carriers unaffected by a hematologic malignancy) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (perifollicular accentuation) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (perifollicular accentuation) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema, severe --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema, severe | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eczema-like lesions (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eczema-like lesions (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:edema of dorsum of hands and feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:edema of dorsum of hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:edema, generalized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:edema, generalized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:edema, generalized perinatal (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:edema, generalized perinatal (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:elastin-rich connective tissue nevi (elastoma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:elastin-rich connective tissue nevi (elastoma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:elastosis perforans serpiginosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:elastosis perforans serpiginosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:elbow dimples --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:elbow dimples | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:enhanced secondary hyperalgesia and flare response on mustard oil application --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:enhanced secondary hyperalgesia and flare response on mustard oil application | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:entire skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:entire skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermal derivative --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermal derivative | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermal hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermal hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermal inclusion cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermal inclusion cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermal ridges absent from palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermal ridges absent from palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermoid inclusion cysts --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermoid inclusion cysts | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermolysis bullosa dystrophica --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermolysis bullosa dystrophica | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermolysis bullosa simplex --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermolysis bullosa simplex | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epidermolytic hyperkeratosis, mild --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epidermolytic hyperkeratosis, mild | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:episodic cold-triggered erythrocyanosis of toes and fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:episodic cold-triggered erythrocyanosis of toes and fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:episodic hyperhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:episodic hyperhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:episodic urticaria --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:episodic urticaria | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epithelial cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epithelial cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:epithelioid and spindle cell nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:epithelioid and spindle cell nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erdheim-chester disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erdheim-chester disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erosion lesion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erosion lesion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erosion, generalized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erosion, generalized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eruptive xanthoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eruptive xanthoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erysipelas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erysipelas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erysipelas (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erysipelas (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema in affected areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema in affected areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema marginatum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema marginatum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema nodosum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema nodosum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema, blisters, pustules (cyclical, explosive episodes) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema, blisters, pustules (cyclical, explosive episodes) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema, cold-induced --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema, cold-induced | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema, mild to moderate (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema, mild to moderate (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythema, residual painless --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythema, residual painless | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous affected skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous affected skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous blotching, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous blotching, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous hyperkeratotic plaques on extremities (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous hyperkeratotic plaques on extremities (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous ichthyotic skin with reticulate pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous ichthyotic skin with reticulate pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous indurated plaques on the shins --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous indurated plaques on the shins | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous malar rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous malar rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous nodular skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous nodular skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous palmoplantar hyperkeratosis, progressive extending onto dorsum of hands and achilles tendon area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous palmoplantar hyperkeratosis, progressive extending onto dorsum of hands and achilles tendon area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous papular skin eruption (infancy) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous papular skin eruption (infancy) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous plaque --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous plaque | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous rash (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous rash (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous skin blotching --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous skin blotching | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous skin lesions in infancy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous skin lesions in infancy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous squamous skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous squamous skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythematous, irregular netlike pattern of vessels --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythematous, irregular netlike pattern of vessels | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythermalgia (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythermalgia (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythroderma (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythroderma (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythroderma, generalized congenital --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythroderma, generalized congenital | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythroderma, patchy, on cheeks and chin (1/4 patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythroderma, patchy, on cheeks and chin (1/4 patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythroderma, psoriasiform --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythroderma, psoriasiform | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythrodermic psoriasis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythrodermic psoriasis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:erythrokeratodermia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:erythrokeratodermia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eschar formation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eschar formation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:exanthema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:exanthema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:excessive salt in sweat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:excessive salt in sweat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:excessive skin folds --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:excessive skin folds | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:excessive skin wrinkling of palms and soles (in one patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:excessive skin wrinkling of palms and soles (in one patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:excessive skin wrinkling on dorsum of hands and fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:excessive skin wrinkling on dorsum of hands and fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:exfoliative dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:exfoliative dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:exophytic, red lesion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:exophytic, red lesion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:extensive cutaneous involvement rarely occurs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:extensive cutaneous involvement rarely occurs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:external ear --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:external ear | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:extreme skin fragility --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:extreme skin fragility | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:extrusion of calcium deposits ('perforating pxe') --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:extrusion of calcium deposits ('perforating pxe') | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eyelid margin cysts (apocrine hidrocystoma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eyelid margin cysts (apocrine hidrocystoma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:eyelid structure --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:eyelid structure | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial angiofibroma (adenoma sebaceum) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial angiofibroma (adenoma sebaceum) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial capillary hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial capillary hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial erythema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial erythema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial milia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial milia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial milia tend to disappear in adulthood --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial milia tend to disappear in adulthood | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial milia, congenital, especially on chin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial milia, congenital, especially on chin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial or extensor involvement in infants and children (major feature) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial or extensor involvement in infants and children (major feature) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial pallor --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial pallor | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial telangiectasia in butterfly midface distribution (exacerbated by sun) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial telangiectasia in butterfly midface distribution (exacerbated by sun) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial trichilemmomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial trichilemmomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:facial xanthomatous eruptions (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:facial xanthomatous eruptions (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fades in adolescence --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fades in adolescence | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fair skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fair skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:familial progressive hyperpigmentation and hypopigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:familial progressive hyperpigmentation and hypopigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fat pad --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fat pad | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fear of cancer of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fear of cancer of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fear of having other skin disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fear of having other skin disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fetal pads of digits --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fetal pads of digits | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fibrofolliculoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fibrofolliculoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fibroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fibroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fibrosis over affected area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fibrosis over affected area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fibrous skin tumor of tuberous sclerosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fibrous skin tumor of tuberous sclerosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine erythrodermic scales, generalized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine erythrodermic scales, generalized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine greyish-white scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine greyish-white scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine white or greyish-white scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine white or greyish-white scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine white or light brown scales on scalp, face, trunk, and limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine white or light brown scales on scalp, face, trunk, and limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine white scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine white scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine whitish scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine whitish scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine whitish scales (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine whitish scales (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine whitish scales over entire surface of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine whitish scales over entire surface of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine whitish scaling on face and trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine whitish scaling on face and trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fine, reticulate skin pigmentation (trunk, palm, and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fine, reticulate skin pigmentation (trunk, palm, and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:finely wrinkled palms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:finely wrinkled palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:finger subcutaneous nodule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:finger subcutaneous nodule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fingerprints, absence of --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fingerprints, absence of | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fissure in skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fissure in skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fissures of soles (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fissures of soles (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fissuring of palms and/or soles in hot or cold weather --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fissuring of palms and/or soles in hot or cold weather | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fistula formation (late complication) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fistula formation (late complication) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fistula, enterocutaneous --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fistula, enterocutaneous | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flares of erythema, scaling, and pustules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flares of erythema, scaling, and pustules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flexion contractures of hands due to severe hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flexion contractures of hands due to severe hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flexural acanthosis nigricans (females, childhood-early adolescence) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flexural acanthosis nigricans (females, childhood-early adolescence) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flexural lichenification in adults (major feature) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flexural lichenification in adults (major feature) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flexural skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flexural skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:florid red complexion (finding) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:florid red complexion (finding) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flushing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flushing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:flushing attacks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:flushing attacks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal dermal aplasia/hypoplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal dermal aplasia/hypoplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal friction-related palmoplantar hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal friction-related palmoplantar hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal hyperkeratosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal hyperkeratosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal keratoderma of soles (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal keratoderma of soles (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal palmoplantar keratoderma on weight-bearing areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal palmoplantar keratoderma on weight-bearing areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal scalp defects with alopecia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal scalp defects with alopecia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:focal skin hypoplasia in face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:focal skin hypoplasia in face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular atrophoderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular atrophoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular atrophoderma (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular atrophoderma (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular atrophoderma affecting the dorsa of the hands and feet, the face, and extensor surfaces of the elbows and knees --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular atrophoderma affecting the dorsa of the hands and feet, the face, and extensor surfaces of the elbows and knees | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular hyperkeratosis (trunk and limbs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular hyperkeratosis (trunk and limbs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular hyperkeratosis of occipital scalp, nape of neck, and extensor surfaces of upper limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular hyperkeratosis of occipital scalp, nape of neck, and extensor surfaces of upper limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular hyperkeratotic papules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular hyperkeratotic papules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular keratosis, generalized (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular keratosis, generalized (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follicular papule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follicular papule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:folliculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:folliculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:folliculitis (back, axilla, pubic region) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:folliculitis (back, axilla, pubic region) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:folliculitis of the scalp, trunk, and extensor surfaces of the extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:folliculitis of the scalp, trunk, and extensor surfaces of the extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:follows blaschko's lines --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:follows blaschko's lines | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:foot callus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:foot callus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:forehead hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:forehead hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fragile skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fragile skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fragile skin with atrophic scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fragile skin with atrophic scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:fragility with blistering (neonatal onset) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:fragility with blistering (neonatal onset) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:freckled skin (in some less dark-skinned individuals) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:freckled skin (in some less dark-skinned individuals) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:freckles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:freckles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:freckles in sun-exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:freckles in sun-exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:freckling in a butterfly pattern on the face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:freckling in a butterfly pattern on the face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:freckling may or may not be present --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:freckling may or may not be present | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:frequent bleeding may occur with trauma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:frequent bleeding may occur with trauma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:frequent staphylococcus aureus infections --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:frequent staphylococcus aureus infections | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:frontal cutaneous lipoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:frontal cutaneous lipoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:frontal hirsutism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:frontal hirsutism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:frostbitten hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:frostbitten hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:furrowed facial skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:furrowed facial skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized bronze hyperpigmentation (present at birth) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized bronze hyperpigmentation (present at birth) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized bruising tendency --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized bruising tendency | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized darkening of the skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized darkening of the skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized epidermolysis (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized epidermolysis (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized erythema (inflammatory type b) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized erythema (inflammatory type b) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized hypopigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized hypopigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized ichthyosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized ichthyosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized peeling skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized peeling skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized pustular psoriasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized pustular psoriasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized skin wrinkling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized skin wrinkling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:generalized swelling/papules/lumps/masses --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:generalized swelling/papules/lumps/masses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:genital porokeratosis, localized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:genital porokeratosis, localized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:giant pigmented hairy nevus, often in lumbosacral distribution --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:giant pigmented hairy nevus, often in lumbosacral distribution | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:giant pigmented nevi, often in lumbosacral region --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:giant pigmented nevi, often in lumbosacral region | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:giant plaque of porokeratosis ptychotropica --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:giant plaque of porokeratosis ptychotropica | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:gilbert disease (disorder) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:gilbert disease (disorder) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:gingival hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:gingival hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:glabellar hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:glabellar hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:glabrous skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:glabrous skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:granular layer hyperplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:granular layer hyperplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:granuloma annulare --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:granuloma annulare | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:granulomatous dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:granulomatous dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:granulomatous dermatitis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:granulomatous dermatitis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:greasy skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:greasy skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hand dermatitis (non-allergic, irritant) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hand dermatitis (non-allergic, irritant) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hard scaly skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hard scaly skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:harlequin fetus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:harlequin fetus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:healed areas are atrophic and hypopigmented --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:healed areas are atrophic and hypopigmented | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangioma (neck and forehead) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangioma (neck and forehead) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangioma, cavernous --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangioma, cavernous | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangiomas (facial, glabellar) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangiomas (facial, glabellar) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangiomas and lymphangiomas of any site --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangiomas and lymphangiomas of any site | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangiomata in at least first branch (ophthalmic) of trigeminal nerve distribution, unilateral, occasionally bilateral --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangiomata in at least first branch (ophthalmic) of trigeminal nerve distribution, unilateral, occasionally bilateral | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangiomata, especially thorax and upper abdomen --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangiomata, especially thorax and upper abdomen | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemangiomatous branchial clefts (extend along sternocleidomastoid muscle) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemangiomatous branchial clefts (extend along sternocleidomastoid muscle) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemorrhagic blisters --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemorrhagic blisters | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hemorrhagic palmar and plantar macules (uncommon) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hemorrhagic palmar and plantar macules (uncommon) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:henoch-schoenlein purpura --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:henoch-schoenlein purpura | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:herpes simplex infections --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:herpes simplex infections | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:herpes zoster disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:herpes zoster disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hidradenitis suppurativa (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hidradenitis suppurativa (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hidrocystoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hidrocystoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:high sweat electrolyte --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:high sweat electrolyte | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hirsutism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hirsutism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:histology shows 'cannonball' distribution of capillary-sized vessels in the dermis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:histology shows 'cannonball' distribution of capillary-sized vessels in the dermis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:histology shows exterior zone of densely packed, small basophilic cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:histology shows exterior zone of densely packed, small basophilic cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:honeycomb keratoderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:honeycomb keratoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:honeycomb palmoplantar keratoderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:honeycomb palmoplantar keratoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:horny papules (face, leg, buttocks) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:horny papules (face, leg, buttocks) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyaline deposition in dermis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyaline deposition in dermis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperalgesia to pressure --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperalgesia to pressure | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperelastic skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperelastic skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperelasticity (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperelasticity (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperextensible skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperextensible skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperextensible skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperextensible skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis (hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis (hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis disorder --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis disorder | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis occurs during pain episodes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis occurs during pain episodes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis of plantar surface (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis of plantar surface (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperhidrosis palmaris et plantaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperhidrosis palmaris et plantaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis (especially extensor surfaces) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis (especially extensor surfaces) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis (palms, soles, elbows, knees) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis (palms, soles, elbows, knees) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis and fissuring around orifices --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis and fissuring around orifices | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of perianal areas, auricles, knuckles, knees, and ankles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of perianal areas, auricles, knuckles, knees, and ankles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of pressure sites of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of pressure sites of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of skin at nipples and umbilicus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of skin at nipples and umbilicus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of the palms (seen in recessive form) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of the palms (seen in recessive form) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of the palms and soles and esophageal papillomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of the palms and soles and esophageal papillomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis of weight-bearing areas of soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis of weight-bearing areas of soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis on dorsal surface of fingers and toes (knuckle pads, in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis on dorsal surface of fingers and toes (knuckle pads, in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis on soles of feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis on soles of feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis over affected area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis over affected area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis over edematous areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis over edematous areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis palmaris and plantaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis palmaris and plantaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis pilaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis pilaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis pilaris may occur --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis pilaris may occur | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis, focal, on the palms and soles (in adulthood in some) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis, focal, on the palms and soles (in adulthood in some) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratosis, particularly on palms and soles of feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratosis, particularly on palms and soles of feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic cutaneous vascular lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic cutaneous vascular lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic dark-brown papules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic dark-brown papules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic lesions of neck, elbows, knees, groin, genitalia, and buttocks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic lesions of neck, elbows, knees, groin, genitalia, and buttocks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic micropapules over dorsum of interphalangeal joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic micropapules over dorsum of interphalangeal joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic papules, dark brown, on neck, chest, and back (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic papules, dark brown, on neck, chest, and back (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic plaques (face, elbow, knees) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic plaques (face, elbow, knees) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic plaques on anterior knee area (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic plaques on anterior knee area (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic plaques on anterolateral ankle area (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic plaques on anterolateral ankle area (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic plaques on trunk and limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic plaques on trunk and limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic porokeratosis (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic porokeratosis (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperkeratotic yellowish papules and plaques arranged linearly on palms and fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperkeratotic yellowish papules and plaques arranged linearly on palms and fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperlinearity of palms (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperlinearity of palms (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypermelanotic macule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypermelanotic macule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation (in patients with kit mutations) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation (in patients with kit mutations) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation (knuckles, elbows, axillae, areolae, pubic area) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation (knuckles, elbows, axillae, areolae, pubic area) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation associated with increased adrenocorticotropic hormone (acth) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation associated with increased adrenocorticotropic hormone (acth) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation in a reticular pattern primarily on flexural skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation in a reticular pattern primarily on flexural skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation in flexure areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation in flexure areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation in sun-exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation in sun-exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmentation of blistered skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmentation of blistered skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented 2 to 5-mm macules mainly on the extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented 2 to 5-mm macules mainly on the extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented erythematous lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented erythematous lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented lesions, 0.2-0.5 cm --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented lesions, 0.2-0.5 cm | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented macules of variable size and shape located in a symmetrical pattern primarily on face, neck, trunk, and dorsa of hands and feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented macules of variable size and shape located in a symmetrical pattern primarily on face, neck, trunk, and dorsa of hands and feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented nevi and streak --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented nevi and streak | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented patches (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented patches (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented patches of skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented patches of skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented rim with long fine hairs encircling the lesions (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented rim with long fine hairs encircling the lesions (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented skin lesions (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented skin lesions (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented skin patches (face, neck, trunk, limbs, lip, oral mucosa, palms, and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented skin patches (face, neck, trunk, limbs, lip, oral mucosa, palms, and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented spots on hands (especially palms), arms, feet (especially plantar areas), legs, and lips --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented spots on hands (especially palms), arms, feet (especially plantar areas), legs, and lips | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented streaks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented streaks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented streaks following lines of blaschko --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented streaks following lines of blaschko | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented whorls --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented whorls | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented/hypopigmented macules (dorsum hands and feet, face) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented/hypopigmented macules (dorsum hands and feet, face) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hyperpigmented/hypopigmented macules (trunk, extremities, occasionally face) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperpigmented/hypopigmented macules (trunk, extremities, occasionally face) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrichosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrichosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrichosis (scalp, arms, legs, back) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrichosis (scalp, arms, legs, back) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrophic keloid-like lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrophic keloid-like lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrophic scar --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrophic scar | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrophic scarring (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrophic scarring (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypertrophy of skin of soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypertrophy of skin of soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis (in most patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis (in most patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis (in patients with hsan2d) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis (in patients with hsan2d) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis and/or heat intolerance --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis and/or heat intolerance | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis may be present --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis may be present | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis or anhidrosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis or anhidrosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis, localized, often on face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis, localized, often on face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypohidrosis/hyperhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypohidrosis/hyperhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmentation (family a) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmentation (family a) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmentation (seen only in deletion cases) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmentation (seen only in deletion cases) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmentation in a reticular pattern primarily on flexural skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmentation in a reticular pattern primarily on flexural skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmentation spots --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmentation spots | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented macules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented macules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented macules on neck, chest, and back (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented macules on neck, chest, and back (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented macules, primarily on extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented macules, primarily on extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented patches (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented patches (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented skin patch --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented skin patch | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented skin patches on arms (vitiligo) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented skin patches on arms (vitiligo) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented spots (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented spots (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypopigmented streaks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypopigmented streaks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic dermal ridges --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic dermal ridges | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic fingertip epidermal ridges --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic fingertip epidermal ridges | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic flexion creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic flexion creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic flexion creases dorsum of hand --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic flexion creases dorsum of hand | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic pilosebaceous units --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic pilosebaceous units | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:hypoplastic-absent sebaceous glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:hypoplastic-absent sebaceous glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyoses --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyoses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosiform areas of skin (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosiform areas of skin (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosiform dermatosis, diffuse generalized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosiform dermatosis, diffuse generalized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosiform erythroderma, congenital --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosiform erythroderma, congenital | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis (in contiguous gene syndrome patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis (in contiguous gene syndrome patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis hystrix --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis hystrix | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis of scalp and flexural areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis of scalp and flexural areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis, diffuse lamellar --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis, diffuse lamellar | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis, generalized, including flexures --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis, generalized, including flexures | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ichthyosis, generalized, with involvement of flexural folds --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ichthyosis, generalized, with involvement of flexural folds | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:icterus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:icterus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:impaired healing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:impaired healing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:impaired would healing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:impaired would healing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:impetigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:impetigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:impetigo-like eruptions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:impetigo-like eruptions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased chloride levels in sweat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased chloride levels in sweat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased fine wrinkles (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased fine wrinkles (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased mast cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased mast cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased number of skin folds (neck, abdomen, axillae) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased number of skin folds (neck, abdomen, axillae) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased pigmented nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased pigmented nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased sweating --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased sweating | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased tendency to bruise --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased tendency to bruise | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased wrinkles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased wrinkles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:increased/decreased skin pigment --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:increased/decreased skin pigment | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:infected finger/toe/paronychia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:infected finger/toe/paronychia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:infra-orbital crease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:infra-orbital crease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:infraorbital fold (dennie-morgan lines) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:infraorbital fold (dennie-morgan lines) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ingrown toenail/other disease of nail --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ingrown toenail/other disease of nail | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:inguinal freckling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:inguinal freckling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:inguinal pterygium, bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:inguinal pterygium, bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:inner zone of enucleated 'shadow' cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:inner zone of enucleated 'shadow' cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:insect bites --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:insect bites | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intentional self-injury --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intentional self-injury | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intercrural pterygium --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intercrural pterygium | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intermittent generalized erythematous papular rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intermittent generalized erythematous papular rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intertrigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intertrigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intolerant of heat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intolerant of heat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:intracytoplasmic vacuoles in basal keratinocytes (with negative oil red o-staining) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:intracytoplasmic vacuoles in basal keratinocytes (with negative oil red o-staining) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:irregular hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:irregular hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:islands of uninvolved skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:islands of uninvolved skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:itching ( in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:itching ( in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (harderoporphyria) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (harderoporphyria) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (in some patients), resolved postpartum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (in some patients), resolved postpartum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (in some) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (in some) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice (sometimes onset in the neonatal period) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice (sometimes onset in the neonatal period) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice due to hemolytic anemia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice due to hemolytic anemia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice during episodes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice during episodes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice, green --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice, green | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice, intermittent (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice, intermittent (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice, neonatal (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice, neonatal (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:jaundice, neonatal or in early childhood --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:jaundice, neonatal or in early childhood | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:junctional epidermolysis bullosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:junctional epidermolysis bullosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:juvenile colloid milium --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:juvenile colloid milium | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keloid --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keloid | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keloid formation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keloid formation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keloid formation in surgical scars --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keloid formation in surgical scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratinized, purple, nodular skin lesions (in 2 of 4 patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratinized, purple, nodular skin lesions (in 2 of 4 patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratinocyte --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratinocyte | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoacanthoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoacanthoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma (palms and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma (palms and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma of margins of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma of margins of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma of soles at pressure points --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma of soles at pressure points | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma, mutilating, of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma, mutilating, of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma, palmoplantar, diffuse --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma, palmoplantar, diffuse | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma, palmoplantar, epidermolytic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma, palmoplantar, epidermolytic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratoderma, striated, on palms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratoderma, striated, on palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis follicularis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis follicularis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis palmaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis palmaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis pilaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis pilaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis pilaris (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis pilaris (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis pilaris of arms and legs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis pilaris of arms and legs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis pilaris of trunk and extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis pilaris of trunk and extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratosis plantaris --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratosis plantaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratotic plaque, periorificial --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratotic plaque, periorificial | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:keratotic plaques (palms) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:keratotic plaques (palms) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:knee dimple --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:knee dimple | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:knuckle pads --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:knuckle pads | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:knuckle pads on dorsal finger and toe joints --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:knuckle pads on dorsal finger and toe joints | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:laceration/cut --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:laceration/cut | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lack of chilblain lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lack of chilblain lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lack of epidermal ridges on palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lack of epidermal ridges on palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lack of perspiration --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lack of perspiration | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lack of scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lack of scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:langerhans cell --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:langerhans cell | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large adherent dark pigmented scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large adherent dark pigmented scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large brownish scales on lower extremities (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large brownish scales on lower extremities (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large cafe au lait spots with irregular margins --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large cafe au lait spots with irregular margins | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large dark plate-like scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large dark plate-like scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large diamond-shaped plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large diamond-shaped plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large hard compact painful masses of keratin at sites of recurrent friction on palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large hard compact painful masses of keratin at sites of recurrent friction on palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:large nevus (greater than 10 cm) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:large nevus (greater than 10 cm) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:larger and darker scales on neck, elbows, and knees (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:larger and darker scales on neck, elbows, and knees (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:larger brownish scaling on neck, buttocks, and legs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:larger brownish scaling on neck, buttocks, and legs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:larger lamellar scales (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:larger lamellar scales (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:leiomyomas are sensitive to light touch --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:leiomyomas are sensitive to light touch | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lentigines may be absent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lentigines may be absent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lentigines may be congenital or develop in first months to years of life --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lentigines may be congenital or develop in first months to years of life | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lentiginosis, generalized (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lentiginosis, generalized (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lentigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lentigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions appear on the trunk and limbs but the face, palms, soles, and mucosa are spared --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions appear on the trunk and limbs but the face, palms, soles, and mucosa are spared | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions are often brownish colored --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions are often brownish colored | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions become purpuric --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions become purpuric | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions become soft and paler with age --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions become soft and paler with age | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions follow the lines of blaschko --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions follow the lines of blaschko | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions occur mainly on extremities, scalp, neck, and trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions occur mainly on extremities, scalp, neck, and trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions occur on the trunk, back, arms, legs, abdomen, buttocks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions occur on the trunk, back, arms, legs, abdomen, buttocks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions often follow blaschko lines --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions often follow blaschko lines | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lesions predominantly on face and limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lesions predominantly on face and limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:leukoplakia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:leukoplakia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:leukoplakia (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:leukoplakia (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:leukoplakia (seen in recessive form) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:leukoplakia (seen in recessive form) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lichenification --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenification | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lichenification of palms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenification of palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lichenified lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenified lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lichenified skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenified skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lichenoid plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lichenoid plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:light complexion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:light complexion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:light skin pigmentation compared to unaffected sibs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:light skin pigmentation compared to unaffected sibs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:light-sensitive dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:light-sensitive dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lighter skin color --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lighter skin color | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:limited dermatologic function --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:limited dermatologic function | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear arrays of macular hyperkeratoses in flexural areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear arrays of macular hyperkeratoses in flexural areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear atrophic hyperpigmented streak on left index finger --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear atrophic hyperpigmented streak on left index finger | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear atrophy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear atrophy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear epidermal nevus (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear epidermal nevus (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear nevus sebaceous, often in midfacial area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear nevus sebaceous, often in midfacial area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear or reticular hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear or reticular hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear plaque-like scales (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear plaque-like scales (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear porokeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear porokeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:linear porokeratosis (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:linear porokeratosis (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lipofibroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lipofibroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lipohypoplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lipohypoplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lipoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lipoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lipoma of skin and subcutaneous tissue of scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lipoma of skin and subcutaneous tissue of scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:livedo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:livedo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:livedo racemosa (usually on trunk and/or lower extremities) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:livedo racemosa (usually on trunk and/or lower extremities) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:livedo reticularis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:livedo reticularis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:livedo reticularis (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:livedo reticularis (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:local swelling/papules/lump/mass --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:local swelling/papules/lump/mass | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localised rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localised rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localized cellulitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localized cellulitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localized cutaneous deposits of superficial fat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localized cutaneous deposits of superficial fat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localized cutaneous necrobiosis lipoidica --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localized cutaneous necrobiosis lipoidica | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localized hives with erythema, edema, and pruritus after repetitive vibratory or stretching stimulation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localized hives with erythema, edema, and pruritus after repetitive vibratory or stretching stimulation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:localized symmetric fixed, yellow- or red-brown hyperkeratotic plaques (extensor surface of extremities, buttocks, and lateral trunk) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:localized symmetric fixed, yellow- or red-brown hyperkeratotic plaques (extensor surface of extremities, buttocks, and lateral trunk) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:longer retraction time after stretching --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:longer retraction time after stretching | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:longitudinal hyperkeratotic lesions along flexor surface of each finger, extending to palm --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:longitudinal hyperkeratotic lesions along flexor surface of each finger, extending to palm | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loose redundant skin (especially of dorsum of hands and feet and anterior abdominal wall) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loose redundant skin (especially of dorsum of hands and feet and anterior abdominal wall) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loose skin at birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loose skin at birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loose volor skin of hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loose volor skin of hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loose, elastic skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loose, elastic skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loose, redundant skin on fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loose, redundant skin on fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:loss of subcutaneous fat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:loss of subcutaneous fat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lymphangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lymphangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lymphatic vessels present at the periphery of lesion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lymphatic vessels present at the periphery of lesion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:lymphedema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:lymphedema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:maceration of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:maceration of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:maculae are homogeneous or telangiectatic and may vary in color from pale pink to red, purple or brown --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:maculae are homogeneous or telangiectatic and may vary in color from pale pink to red, purple or brown | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:maculae can be a few millimeters to several centimeters in diameter and can be surrounded by pale halo with punctate red spot in middle --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:maculae can be a few millimeters to several centimeters in diameter and can be surrounded by pale halo with punctate red spot in middle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:macular hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:macular hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:macular hypopigmented whorls, streaks, and patches --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:macular hypopigmented whorls, streaks, and patches | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:maculopapular eruption, diffuse --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:maculopapular eruption, diffuse | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:maculopapular rash, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:maculopapular rash, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:malar flush --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:malar flush | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:malar rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:malar rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:malignant neoplasm of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:malignant neoplasm of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:marbled skin due to telangiectasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:marbled skin due to telangiectasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:marked bruisability --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:marked bruisability | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:marked skin pallor --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:marked skin pallor | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mast cell degranulation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mast cell degranulation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mature adipocytes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mature adipocytes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mechanically fragile skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mechanically fragile skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:melanocytic nevus of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:melanocytic nevus of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:melanocytic skin tumors/papules, skin-colored to reddish-brown, dome-shaped or pedunculated, well circumscribed with an average size of 5 mm (in 2 families) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:melanocytic skin tumors/papules, skin-colored to reddish-brown, dome-shaped or pedunculated, well circumscribed with an average size of 5 mm (in 2 families) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:midface capillary hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:midface capillary hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:midfrontal capillary hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:midfrontal capillary hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:midline facial capillary hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:midline facial capillary hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:migratory ichthyosiform dermatosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:migratory ichthyosiform dermatosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:migratory plaques of thickened, sharply demarcated erythema and hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:migratory plaques of thickened, sharply demarcated erythema and hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:migratory rashes, painful --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:migratory rashes, painful | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild atrophic scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild atrophic scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild diffuse ichthyosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild diffuse ichthyosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild hyperkeratosis of palms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild hyperkeratosis of palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild hypopigmentation (in light-skinned individuals) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild hypopigmentation (in light-skinned individuals) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild lamellar ichthyosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild lamellar ichthyosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild localized pigmentation abnormalities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild localized pigmentation abnormalities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild skin hyperextensibility --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild skin hyperextensibility | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild tissue fragility --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild tissue fragility | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild-moderate bruisability --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild-moderate bruisability | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mild/severe skin hypopigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mild/severe skin hypopigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mildly extensible skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mildly extensible skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:milia (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:milia (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:milia (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:milia (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:milia of upper face and ears (infancy) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:milia of upper face and ears (infancy) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:milium cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:milium cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:milky white skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:milky white skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:minimal or absent scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:minimal or absent scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:moderate erythroderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:moderate erythroderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:moderate scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:moderate scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:moderate to severe acne --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:moderate to severe acne | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:molluscoid pseudotumors --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:molluscoid pseudotumors | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:molluscum contagiosum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:molluscum contagiosum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:moniliasis/candida (excluding x72 y75) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:moniliasis/candida (excluding x72 y75) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:morbilliform eruption --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:morbilliform eruption | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:most evident on lower legs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:most evident on lower legs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mottled pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mottled pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mottled pigmentation of photoexposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mottled pigmentation of photoexposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mottled pigmentation of the trunk and proximal extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mottled pigmentation of the trunk and proximal extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mucocutaneous candidiasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mucocutaneous candidiasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mucosal lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mucosal lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mucosal lesions affecting all regions (i.e., oral, nasal, vaginal, anal, bladder, conjunctival regions) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mucosal lesions affecting all regions (i.e., oral, nasal, vaginal, anal, bladder, conjunctival regions) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mulitple papules (1-2 mm skin colored and hyperpigmented) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mulitple papules (1-2 mm skin colored and hyperpigmented) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple asymptomatic papules with atrophic white scar-like centers surrounded by telangiectatic borders --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple asymptomatic papules with atrophic white scar-like centers surrounded by telangiectatic borders | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple facial papules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple facial papules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple gingival papules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple gingival papules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple lentigines --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple lentigines | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple nevi (face and torso) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple nevi (face and torso) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple nevi (up to hundreds) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple nevi (up to hundreds) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple papules (milium-like, comedo-like) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple papules (milium-like, comedo-like) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple pigmented moles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple pigmented moles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple pterygia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple pterygia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple skin tags --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple skin tags | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple small nevi (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple small nevi (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple, asymptomatic dermal cysts (trunk, proximal extremities, neck, axillae, inguinal region, scalp) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple, asymptomatic dermal cysts (trunk, proximal extremities, neck, axillae, inguinal region, scalp) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple, flat, skin-colored warty papules (2-4mm in diameter on dorsum hands, feet, knees, and elbows) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple, flat, skin-colored warty papules (2-4mm in diameter on dorsum hands, feet, knees, and elbows) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple, red-blue, soft, compressible vascular papules or macules (especially on trunk or upper arms) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple, red-blue, soft, compressible vascular papules or macules (especially on trunk or upper arms) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:multiple, small punctate keratoses (palms and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:multiple, small punctate keratoses (palms and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:mutilating skin deformity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:mutilating skin deformity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:myxedema (untreated hypothyroidism) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:myxedema (untreated hypothyroidism) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:necrosis leading to amputation (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:necrosis leading to amputation (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:necrotic skin ulcers (in 1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:necrotic skin ulcers (in 1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal acral blistering --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal acral blistering | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal blisters and erosions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal blisters and erosions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal collodion skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal collodion skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal cyanosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal cyanosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal jaundice --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal jaundice | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neonatal purpura fulminans --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neonatal purpura fulminans | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:netherton syndrome --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:netherton syndrome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neurofibroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neurofibroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neurofibromas may or may not be present --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neurofibromas may or may not be present | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neurofibromas, cutaneous (86%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neurofibromas, cutaneous (86%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:neurofibromas, subcutaneous (76%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:neurofibromas, subcutaneous (76%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevi flammei (philtrum, nape of neck, forehead) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevi flammei (philtrum, nape of neck, forehead) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus flammeus (eyelids and nape of neck) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus flammeus (eyelids and nape of neck) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus flammeus of the forehead --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus flammeus of the forehead | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus flammeus simplex on the forehead --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus flammeus simplex on the forehead | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus flammus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus flammus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus, blue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus, blue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus, epidermal (disorder) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus, epidermal (disorder) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nevus/mole --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nevus/mole | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nipple dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nipple dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no ability to tan --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no ability to tan | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no abnormalities of sweating --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no abnormalities of sweating | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no cutaneous photosensitivity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no cutaneous photosensitivity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no easy bruisability --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no easy bruisability | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no erythema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no erythema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no hemorrhage --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no hemorrhage | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no hyperhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no hyperhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no ichthyosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no ichthyosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no increased bruisability --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no increased bruisability | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no inflammatory or bullous skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no inflammatory or bullous skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no mucosal vesicles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no mucosal vesicles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no palmoplantar hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no palmoplantar hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no palmoplantar keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no palmoplantar keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no pruritis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no pruritis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no skin hyperelasticity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no skin hyperelasticity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no systemic vascular lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no systemic vascular lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:no tanning --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:no tanning | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nodular lesion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nodular lesion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nodular skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nodular skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nodule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nodule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nodule show lipid-laden macrophages --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nodule show lipid-laden macrophages | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:non pruritic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:non pruritic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:non-actinic disseminated superficial porokeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:non-actinic disseminated superficial porokeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:non-glabrous skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:non-glabrous skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:non-purpuric punctate and linear erythematous rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:non-purpuric punctate and linear erythematous rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:non-scarring skin blistering (hands, feet, elbow, knee - onset in adolescence) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:non-scarring skin blistering (hands, feet, elbow, knee - onset in adolescence) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nonbullous ichthyosiform erythroderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nonbullous ichthyosiform erythroderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nonmelanoma skin cancer (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nonmelanoma skin cancer (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:nonscarring blisters (hand, feet, forearms) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:nonscarring blisters (hand, feet, forearms) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal numbers of sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal numbers of sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal skin (no palmoplantar keratoderma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal skin (no palmoplantar keratoderma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal sweat electrolytes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal sweat electrolytes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal sweating --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal sweating | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:normal sweating capacity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:normal sweating capacity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:numbness, pain, and tingling of the fingers in response to cold --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:numbness, pain, and tingling of the fingers in response to cold | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:numerous 'confetti-like' scattered patches of normal skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:numerous 'confetti-like' scattered patches of normal skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:numerous congenital melanocytic nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:numerous congenital melanocytic nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:numerous nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:numerous nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:numerous pigmented freckles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:numerous pigmented freckles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:occasional cafe-au-lait spots --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:occasional cafe-au-lait spots | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:occasional neurofibromas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:occasional neurofibromas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:occurs in linear distribution --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:occurs in linear distribution | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:odoriferous,, hypertrophic plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:odoriferous,, hypertrophic plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:onset birth-newborn period --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:onset birth-newborn period | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:orthokeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:orthokeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:orthostatic acrocyanosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:orthostatic acrocyanosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other benign neoplasm of skin, unspecified --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other benign neoplasm of skin, unspecified | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other changes in skin color --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other changes in skin color | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other dermatologic congenital anomalies --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other dermatologic congenital anomalies | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other disorders of the skin and subcutaneous tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other disorders of the skin and subcutaneous tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other infectious skin disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other infectious skin disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other injury to skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other injury to skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other localized skin infection --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other localized skin infection | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other symptom/complaint skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other symptom/complaint skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:other/unspecified neoplasm skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:other/unspecified neoplasm skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:overlapping lesion of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:overlapping lesion of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pachyderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pachyderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pain/tenderness of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pain/tenderness of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:painful bluish-red papules or nodules (fingers, toes, nose, cheek, ears) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:painful bluish-red papules or nodules (fingers, toes, nose, cheek, ears) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:painful, fleshy papules or nodules (hands, scalp, ears, perinasal area) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:painful, fleshy papules or nodules (hands, scalp, ears, perinasal area) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pale, sensitive skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pale, sensitive skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pale-gray skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pale-gray skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pallor --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pallor | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pallor (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pallor (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pallor during episodes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pallor during episodes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pallor of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pallor of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar creases, fine to acrogeria-like --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar creases, fine to acrogeria-like | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar erythema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar erythema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar hyperhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar hyperhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar hyperlinearity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar hyperlinearity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar pit --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar pit | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar telangiectasias (described in 1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar telangiectasias (described in 1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar wrinkling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar wrinkling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmar xanthomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmar xanthomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar cutis gyrata --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar cutis gyrata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar cutis laxa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar cutis laxa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar epidermolytic hyperkeratosis along blaschko lines (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar epidermolytic hyperkeratosis along blaschko lines (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperhidrosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperhidrosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperkeratosis, mild (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperkeratosis, mild (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperkeratosis, severe --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperkeratosis, severe | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperlinearity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperlinearity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperlinearity, marked --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperlinearity, marked | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar hyperlinearity, marked (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar hyperlinearity, marked (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma (mild in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma (mild in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma, diffuse (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, diffuse (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma, mild --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, mild | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma, mild (in homozygous patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, mild (in homozygous patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma, mild (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, mild (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratoderma, patchy (>50%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratoderma, patchy (>50%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratodermia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratodermia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar keratosis with erythema and scale --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar keratosis with erythema and scale | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palmoplantar pits --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palmoplantar pits | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:palms, soles, and oral mucosa are not involved --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:palms, soles, and oral mucosa are not involved | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:panniculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:panniculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomas (perioral, nasal, and anal regions) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomas (perioral, nasal, and anal regions) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis of affected area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis of affected area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis over affected area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis over affected area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis over edematous areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis over edematous areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis, confluent centrally, erythematous turning brown later --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis, confluent centrally, erythematous turning brown later | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papillomatosis, reticular on the periphery, 1 to 2-mm growing to 4-5-mm and coalescing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papillomatosis, reticular on the periphery, 1 to 2-mm growing to 4-5-mm and coalescing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papular keratoderma, mild --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papular keratoderma, mild | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papules enlarge centrifugally to form central atrophic area with an irregular keratotic ridge --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papules enlarge centrifugally to form central atrophic area with an irregular keratotic ridge | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papules enlarge centrifugally to form central atrophic area with an irregular peripheral keratotic ridge --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papules enlarge centrifugally to form central atrophic area with an irregular peripheral keratotic ridge | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papules, firm, flat or dome-shaped, skin-colored some with a hair at or just outside the periphery and/or telangiectatic surface --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papules, firm, flat or dome-shaped, skin-colored some with a hair at or just outside the periphery and/or telangiectatic surface | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papules, keratotic follicular --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papules, keratotic follicular | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:papulosquamous erythematous plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:papulosquamous erythematous plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:paradoxical sweating response (sweating induced by cold exposure, inability to sweat in hot weather) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:paradoxical sweating response (sweating induced by cold exposure, inability to sweat in hot weather) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:parakeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:parakeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:partial anhidrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:partial anhidrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:patchy vitiligo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:patchy vitiligo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:patchy, reticular stains --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:patchy, reticular stains | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:peau d'orange --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:peau d'orange | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pebbly skin lesions on back, upper arms, and thigh --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pebbly skin lesions on back, upper arms, and thigh | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pediculosis/other skin infestation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pediculosis/other skin infestation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:peeling of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:peeling of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:perianal erythema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:perianal erythema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:perianal skin tags --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:perianal skin tags | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:periarticular subcutaneous nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:periarticular subcutaneous nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:perinasal or perioral nonhealing crusting of the skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:perinasal or perioral nonhealing crusting of the skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:perineal intertrigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:perineal intertrigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:perioral erythema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:perioral erythema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:periorbital hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:periorbital hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:periorbital wrinkles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:periorbital wrinkles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:periorificial hyperkeratotic lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:periorificial hyperkeratotic lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:peristomal skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:peristomal skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:petechiae --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:petechiae | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:petechiae (less common) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:petechiae (less common) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:petechiae and purpura do not occur --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:petechiae and purpura do not occur | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:petechiae, congenital systemic (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:petechiae, congenital systemic (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:photosensitivity (harderoporphyria and hcp) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:photosensitivity (harderoporphyria and hcp) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:photosensitivity bullous dermatitis (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:photosensitivity bullous dermatitis (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:photosensitivity of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:photosensitivity of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:piebaldism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:piebaldism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentary abnormalities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentary abnormalities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentary abnormalities (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentary abnormalities (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentary changes on the shins (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentary changes on the shins (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentation abnormalities (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentation abnormalities (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmentation abnormalities (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmentation abnormalities (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pigmented lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pigmented lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pilo-sebaceous apparatus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pilo-sebaceous apparatus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pilomatrixoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pilomatrixoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pilonidal cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pilonidal cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pilonidal cyst/fistula --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pilonidal cyst/fistula | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pits of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pits of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pitted, perioral acneiform scars --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pitted, perioral acneiform scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pityriasis alba --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pityriasis alba | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pityriasis rosea --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pityriasis rosea | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:planar xanthomas (detroit type 107680.0011) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:planar xanthomas (detroit type 107680.0011) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:planar xanthomas in homozygotes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:planar xanthomas in homozygotes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar blistering --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar blistering | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar keratoderma (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar keratoderma (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar pits --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar pits | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar softness --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar softness | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plantar wart --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plantar wart | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plaque-like facial hemangioma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plaque-like facial hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plaque-like scaling skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plaque-like scaling skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plaques, erythematous, covered with fine powdery scales --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plaques, erythematous, covered with fine powdery scales | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plexiform neurofibroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plexiform neurofibroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:plexiform neurofibroma (76%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:plexiform neurofibroma (76%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poikiloderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poikiloderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poikiloderma (atrophic plaques with telangiectasia) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poikiloderma (atrophic plaques with telangiectasia) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poor healing with abnormal scarring (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poor healing with abnormal scarring (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poor sweating in response to heat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poor sweating in response to heat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poor wound healing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poor wound healing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poorly defined palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poorly defined palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:poorly developed palmar creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:poorly developed palmar creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:popliteal pterygium --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:popliteal pterygium | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:popliteal pterygium, bilateral --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:popliteal pterygium, bilateral | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:porokeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:porokeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:porokeratosis of mibelli --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:porokeratosis of mibelli | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:porokeratosis, disseminated superficial actinic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:porokeratosis, disseminated superficial actinic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:port-wine stain --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:port-wine stain | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:positive skin test reaction to seminal fluid --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:positive skin test reaction to seminal fluid | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:postauricular crescent-shaped hypoplastic skin lesion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:postauricular crescent-shaped hypoplastic skin lesion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:posterior midline scalp defects --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:posterior midline scalp defects | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:postoperative hemorrhage --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:postoperative hemorrhage | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:premature aging (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:premature aging (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:premature aging, mild --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:premature aging, mild | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prepuce --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prepuce | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pretibial dimples --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pretibial dimples | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pretibial pigmented granulomatous plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pretibial pigmented granulomatous plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:primarily affects trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:primarily affects trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:profuse pigmented skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:profuse pigmented skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:profuse sweating of the upper body induced by cold exposure --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:profuse sweating of the upper body induced by cold exposure | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progeric skin changes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progeric skin changes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progression of skin lesions - --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progression of skin lesions - | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progressive cutis verticis gyrata --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progressive cutis verticis gyrata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progressive generalized skin erosions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progressive generalized skin erosions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progressive reticulate hyperpigmentation (axillae, groin, perineal, perianal) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progressive reticulate hyperpigmentation (axillae, groin, perineal, perianal) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:progressive vitiligo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:progressive vitiligo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:proliferating cells show nuclear expression of lymphoid enhancer binding factor-1 (lef1, 153245) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:proliferating cells show nuclear expression of lymphoid enhancer binding factor-1 (lef1, 153245) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:proliferation of spindle cells --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:proliferation of spindle cells | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prolonged capillary refill --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prolonged capillary refill | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent fingerpads (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent fingerpads (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent fingertip pads --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent fingertip pads | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent palmar flexion creases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent palmar flexion creases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent scalp veins --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent scalp veins | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent superficial blood vessels --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent superficial blood vessels | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent superficial blood vessels due to thin skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent superficial blood vessels due to thin skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent superficial veins --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent superficial veins | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent superficial venous pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent superficial venous pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent vasculature (nose and forehead) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent vasculature (nose and forehead) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent veins --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent veins | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent veins (especially over scalp and limbs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent veins (especially over scalp and limbs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent veins on scalp, trunk, and/or extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent veins on scalp, trunk, and/or extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent venous markings --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent venous markings | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prominent venous pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prominent venous pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:prurigo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:prurigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritic eczematous lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritic eczematous lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritic hyperkeratotic scars (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritic hyperkeratotic scars (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritic ichthyosis (onset birth to first several months) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritic ichthyosis (onset birth to first several months) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritis, cold-induced --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritis, cold-induced | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritis, intense --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritis, intense | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus (inflammatory type b) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus (inflammatory type b) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus (major feature) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus (major feature) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus during pregnancy, resolves postpartum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus during pregnancy, resolves postpartum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus in affected areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus in affected areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus of scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus of scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus of skin lesions, severe --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus of skin lesions, severe | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus secondary to liver disease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus secondary to liver disease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pruritus, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pruritus, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pseudoainhum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pseudoainhum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pseudoainhum of fifth toes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pseudoainhum of fifth toes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pseudoxanthomatous skin lesions (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pseudoxanthomatous skin lesions (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasiform dermatitis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform dermatitis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasiform lesions (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform lesions (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasiform plaques --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform plaques | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasiform rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasiform skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasiform skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:psoriasis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:psoriasis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygia of axillae (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygia of axillae (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygia of digits, neck, axillae, antecubital, popliteal, intercrural areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygia of digits, neck, axillae, antecubital, popliteal, intercrural areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygia of elbows (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygia of elbows (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygia of groin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygia of groin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygia of neck (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygia of neck (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium (elbows and knees) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium (elbows and knees) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium of axilla (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium of axilla (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium of bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium of bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium of elbow, bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium of elbow, bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pterygium of wrist, bilateral (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pterygium of wrist, bilateral (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punch-like skin defects --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punch-like skin defects | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punctate keratitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punctate keratitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punctate keratoses (palms and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punctate keratoses (palms and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punctate palmoplantar hyperkeratosis (later onset) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punctate palmoplantar hyperkeratosis (later onset) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punctate palmoplantar keratoderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punctate palmoplantar keratoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:punctate vasculitis skin lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:punctate vasculitis skin lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:purpura --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:purpura | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:purpuric rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:purpuric rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pustular rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pustular rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pustule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pustule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pustulosis or pustular psoriasis, generalized --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pustulosis or pustular psoriasis, generalized | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pyoderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pyoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pyoderma gangrenosum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pyoderma gangrenosum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:pyramidal skinfold of halluces --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:pyramidal skinfold of halluces | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:raised, firm, hairless posterior scalp nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:raised, firm, hairless posterior scalp nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:raised, scaly, and/or hyperkeratotic areas of skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:raised, scaly, and/or hyperkeratotic areas of skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rare skin cancers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rare skin cancers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash (erythematous macules or papules) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash (erythematous macules or papules) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash erythematous --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash erythematous | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash may or may not be pruritic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash may or may not be pruritic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash scaly --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash scaly | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rash, urticarial, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rash, urticarial, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:raynaud phenomenon --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:raynaud phenomenon | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:raynaud phenomenon (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:raynaud phenomenon (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent bacterial skin infections --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent bacterial skin infections | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent cellulitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent cellulitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent shingles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent shingles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent skin abscesses --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent skin abscesses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent skin abscesses (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent skin abscesses (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent skin infections --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent skin infections | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:recurrent skin ulcerations (face, trunk, limbs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:recurrent skin ulcerations (face, trunk, limbs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:red mucosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:red mucosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:red, cracking, peeling skin at birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:red, cracking, peeling skin at birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:red, raised, scaly skin patches (elbows, knees, scalp) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:red, raised, scaly skin patches (elbows, knees, scalp) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:red-violet macular atrophy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:red-violet macular atrophy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reddish discoloration, episodic, associated with pain --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reddish discoloration, episodic, associated with pain | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reddish or purplish skin discoloration, episodic, associated with pain --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reddish or purplish skin discoloration, episodic, associated with pain | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redness --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redness | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reduced axillary apocrine secretion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced axillary apocrine secretion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reduced skin elasticity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced skin elasticity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reduced subcutaneous adipose tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced subcutaneous adipose tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reduced sweating of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reduced sweating of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redundant connective tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant connective tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redundant folds --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant folds | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redundant palmar skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant palmar skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redundant skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:redundant skin in infancy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:redundant skin in infancy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:residual erythema after healing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:residual erythema after healing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:residual hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:residual hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:residual postinflammatory hyperpigmentation, moderate --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:residual postinflammatory hyperpigmentation, moderate | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:residual slightly atrophic scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:residual slightly atrophic scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticular hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticular hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticular hyperpigmentation (neck) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticular hyperpigmentation (neck) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticular pigmentation pattern --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticular pigmentation pattern | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticular skin pigmentation (classic feature, nola3 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticular skin pigmentation (classic feature, nola3 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate hyperpigmentation (periocular, perioral, chest, neck, abdomen) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate hyperpigmentation (periocular, perioral, chest, neck, abdomen) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate hyperpigmentation (primarily trunk) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate hyperpigmentation (primarily trunk) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate hyperpigmentation composed of 1- to 5-mm light brown spots with clearly defined borders that may coalesce --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate hyperpigmentation composed of 1- to 5-mm light brown spots with clearly defined borders that may coalesce | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate hyperpigmented macules which darken over time and appear initially on dorsa of hands and feet but progress to flexor aspects of proximal extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate hyperpigmented macules which darken over time and appear initially on dorsa of hands and feet but progress to flexor aspects of proximal extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate ichthyosis (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate ichthyosis (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate pigmented skin abnormalities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate pigmented skin abnormalities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulate skin pigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulate skin pigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulated pigmentation (seen in recessive form) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulated pigmentation (seen in recessive form) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulated skin pigmentation, predominantly on face, neck, chest, arms (94% male patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulated skin pigmentation, predominantly on face, neck, chest, arms (94% male patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:reticulolinear skin defects over face and neck (4/4 patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:reticulolinear skin defects over face and neck (4/4 patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rhytide of forehead --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rhytide of forehead | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rough, thick palmar skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rough, thick palmar skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:rubbery feel of the nose and chin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:rubbery feel of the nose and chin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:s. epidermidis only microorganism isolated --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:s. epidermidis only microorganism isolated | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sacral dimple --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sacral dimple | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sacral dimple (2 patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sacral dimple (2 patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sacral dimple (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sacral dimple (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sacral striae --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sacral striae | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scabies and other acariases --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scabies and other acariases | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalding burn --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalding burn | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scales on scalp (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scales on scalp (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scaling, hyperchromic spots on limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scaling, hyperchromic spots on limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalp defect --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp defect | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalp dryness --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp dryness | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalp erosions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp erosions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalp sinus formation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp sinus formation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scalp structure --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scalp structure | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scaly skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scaly skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scaly skin rash over the perineum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scaly skin rash over the perineum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scarring (late complication) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scarring (late complication) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:schwannoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:schwannoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sclerodactyly --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sclerodactyly | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scleroderma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scleroderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scleroderma-like change --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scleroderma-like change | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scleroderma-like secondary cutaneous sclerosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scleroderma-like secondary cutaneous sclerosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scleroderma-like skin, especially of face and distal extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scleroderma-like skin, especially of face and distal extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sclerodermatous skin changes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sclerodermatous skin changes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sclerosis of digits (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sclerosis of digits (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sclerotic soft tissue over affected bones --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sclerotic soft tissue over affected bones | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:scrotum --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:scrotum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sebaceous cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sebaceous cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sebaceous cysts (buttocks and perineum) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sebaceous cysts (buttocks and perineum) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sebaceous gland tumors --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sebaceous gland tumors | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sebaceous glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sebaceous glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sebaceous hyperplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sebaceous hyperplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrhea (35% of adults) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrhea (35% of adults) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrheic dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrheic dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrheic dermatitis (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrheic dermatitis (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrheic dermatitis in infancy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrheic dermatitis in infancy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrheic dermatitis of scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrheic dermatitis of scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:seborrheic keratosis-like papules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:seborrheic keratosis-like papules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:self-healing collodion baby (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:self-healing collodion baby (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sensitivity to cold with paresthesias --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sensitivity to cold with paresthesias | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe acne (23% of adults) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe acne (23% of adults) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe atopic dermatitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe atopic dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe bullous blistering lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe bullous blistering lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe cystic acne --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe cystic acne | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe facial acne (in female patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe facial acne (in female patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe photosensitivity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe photosensitivity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:severe progressive ulceration of lower extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:severe progressive ulceration of lower extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:shagreen patch --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:shagreen patch | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:shallow indolent cutaneous ulcers (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:shallow indolent cutaneous ulcers (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sharp midline demarcation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sharp midline demarcation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:shiny, taut, erythematous skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:shiny, taut, erythematous skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:simian crease (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:simian crease (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:single transverse palmar crease --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:single transverse palmar crease | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:single transverse palmar crease (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:single transverse palmar crease (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:single, bilateral, symmetric papular/nodular lesion in the midline plantar region of the heel (0.5 - 1 cm diameter) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:single, bilateral, symmetric papular/nodular lesion in the midline plantar region of the heel (0.5 - 1 cm diameter) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:size variation (1 x 1 to 6 x 4 cm) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:size variation (1 x 1 to 6 x 4 cm) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin absorption --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin absorption | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin appearance normal (finding) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin appearance normal (finding) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin appendage structure --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin appendage structure | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin appendages (periorbital, face, thorax, rarely on trunk) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin appendages (periorbital, face, thorax, rarely on trunk) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin atrophy (especially over hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin atrophy (especially over hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin atrophy (over nose and scalp sutural areas) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin atrophy (over nose and scalp sutural areas) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin atrophy over affected bones --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin atrophy over affected bones | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin biopsy shows noncaseating granulomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin biopsy shows noncaseating granulomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin blistering, intermittent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin blistering, intermittent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin blisters --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin blisters | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin blisters and erosions (neck, perianal, submaxillary, groin, axilla, popliteal fossa) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin blisters and erosions (neck, perianal, submaxillary, groin, axilla, popliteal fossa) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin cell --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin cell | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin changes worse in areas of lower skin temperature --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin changes worse in areas of lower skin temperature | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin derivative --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin derivative | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin dimple (lower back) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin dimple (lower back) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin dimple over apex of long bone angulation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin dimple over apex of long bone angulation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin dimples on upper thighs (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin dimples on upper thighs (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin diseases, infectious --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin diseases, infectious | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin erosion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin erosion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin fissures (groin, axilla, neck) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin fissures (groin, axilla, neck) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin flushing, episodic, associated with pain --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin flushing, episodic, associated with pain | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin folds or creases (neck or forearm) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin folds or creases (neck or forearm) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin foreign body --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin foreign body | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin fragility with non-scarring blistering --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin fragility with non-scarring blistering | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin hyperlaxity (males) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin hyperlaxity (males) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin hypertrophy, particularly in flexural areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin hypertrophy, particularly in flexural areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin hypopigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin hypopigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin lacks elastic recoil --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin lacks elastic recoil | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin lesions are usually symmetrical --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin lesions are usually symmetrical | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin lesions follow the lines of blaschko --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin lesions follow the lines of blaschko | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin may redden during episodes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin may redden during episodes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin mottling due to poor perfusion --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin mottling due to poor perfusion | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin necrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin necrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin nodules - fingers, elbows, nose, ears (onset infancy-childhood) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin nodules - fingers, elbows, nose, ears (onset infancy-childhood) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of female human body --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of female human body | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of left lower limb --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of left lower limb | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of left upper limb --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of left upper limb | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of lip --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of lip | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of male human body --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of male human body | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of neck --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of neck | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of part of limb --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of part of limb | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of right lower limb --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of right lower limb | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of right upper limb --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of right upper limb | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of scalp and neck --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of scalp and neck | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of the axilla --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of the axilla | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of the face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of the face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of the lower limb and hip --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of the lower limb and hip | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of the upper limb and shoulder --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of the upper limb and shoulder | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin of trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin of trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin over joint surfaces of hands and feet is thick, red, and edematous --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin over joint surfaces of hands and feet is thick, red, and edematous | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin part --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin part | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin peeling/scaling (newborn) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin peeling/scaling (newborn) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin pigmentation - finding --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin pigmentation - finding | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin retraction --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin retraction | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin rough --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin rough | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin structure of back --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin structure of back | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin structure of ear --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin structure of ear | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin structure of head --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin structure of head | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin tag --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin tag | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin tags on chest --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin tags on chest | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin tags on genitalia (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin tags on genitalia (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin tags on palms (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin tags on palms (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin tags on the upper part of the auricle --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin tags on the upper part of the auricle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin ulcer --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin ulcer | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin ulcerations (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin ulcerations (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin wrinkling --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin wrinkling | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:skin wrinkling (limited to dorsum of hands and feet and abdomen) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:skin wrinkling (limited to dorsum of hands and feet and abdomen) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:slight erythema of face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:slight erythema of face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:slow-healing wounds due to painless injuries --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:slow-healing wounds due to painless injuries | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small areas of alopecia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small areas of alopecia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small conically shaped papules (1 to 3 mm in diameter) located on face, neck, trunk, and limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small conically shaped papules (1 to 3 mm in diameter) located on face, neck, trunk, and limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small hemorrhagic blisters on hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small hemorrhagic blisters on hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small nodular skin-tags --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small nodular skin-tags | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small papules on sun-exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small papules on sun-exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small pterygia (axillary, popliteal) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small pterygia (axillary, popliteal) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small, annular, anhidrotic keratotic lesions located predominantly on sun-exposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small, annular, anhidrotic keratotic lesions located predominantly on sun-exposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small, pit-like, atrophic areas (0.25-2.0mm) predominantly on cheeks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small, pit-like, atrophic areas (0.25-2.0mm) predominantly on cheeks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small, red lesion, may increase in size with age --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small, red lesion, may increase in size with age | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:small, yellow papules (mouth, neck, axilla, elbows, groin, periumbilical region) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:small, yellow papules (mouth, neck, axilla, elbows, groin, periumbilical region) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:smooth, thin, dry skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:smooth, thin, dry skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:smooth, waxy, thick skin over palms and soles, desquamating in large flakes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:smooth, waxy, thick skin over palms and soles, desquamating in large flakes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft and lax skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft and lax skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft thin skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft thin skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft tissue calcinosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft tissue calcinosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft velvety skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft velvety skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft with easy bruising (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft with easy bruising (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft, doughy skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft, doughy skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft, redundant skin (especially facial) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft, redundant skin (especially facial) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:soft, thin skin (1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:soft, thin skin (1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sparing of flexure areas, palms, and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sparing of flexure areas, palms, and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sparse axillary and facial hair --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sparse axillary and facial hair | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sparse dermal ridges (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sparse dermal ridges (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:speckled lentiginous nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:speckled lentiginous nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spheroids --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spheroids | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spiky hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spiky hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spiky hyperkeratotic lesions on ankles, elbows, and popliteal fossae --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spiky hyperkeratotic lesions on ankles, elbows, and popliteal fossae | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spiny follicular plugging --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spiny follicular plugging | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spiradenoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spiradenoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:split anchoring plaques of desmosomes in the granular layer (transmission electron microscopy (tem)) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:split anchoring plaques of desmosomes in the granular layer (transmission electron microscopy (tem)) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spontaneous hematomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spontaneous hematomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spontaneous, non-scarring healing --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spontaneous, non-scarring healing | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spotted and reticulate pigmentation of flexural areas of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spotted and reticulate pigmentation of flexural areas of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spotty hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spotty hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:spotty hypopigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:spotty hypopigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:squamous epitheliomas, multiple --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:squamous epitheliomas, multiple | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:squamous pityriasiform appearance of scalp --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:squamous pityriasiform appearance of scalp | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stage 1 - skin erythema, vesicles, pustules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stage 1 - skin erythema, vesicles, pustules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stage 2 - skin papules, verrucous lesions, hyperkeratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stage 2 - skin papules, verrucous lesions, hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stage 3 - skin hyperpigmentation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stage 3 - skin hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stage 4 - skin pallor, atrophy, and scarring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stage 4 - skin pallor, atrophy, and scarring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:starfish keratoses (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:starfish keratoses (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:starfish-like acral keratoses (knuckles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:starfish-like acral keratoses (knuckles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stasis ulcers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stasis ulcers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:steatocystoma multiplex --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:steatocystoma multiplex | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:steatocystomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:steatocystomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sterile abscesses at site of parenteral injection --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sterile abscesses at site of parenteral injection | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sterile pustules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sterile pustules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stevens-johnson syndrome --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stevens-johnson syndrome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stiff skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stiff skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:strawberry nevus of skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:strawberry nevus of skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:streaks and whorls --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:streaks and whorls | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:stretched skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:stretched skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:striated keratoderma of palms (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:striated keratoderma of palms (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:striated lichenoid keratoses in major flexural folds --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:striated lichenoid keratoses in major flexural folds | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous calcification --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous calcification | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous connective tissue nevi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous connective tissue nevi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous infections, recurrent, with fistula formation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous infections, recurrent, with fistula formation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous lipoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous lipoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous lipomas, well-circumscribed and painful --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous lipomas, well-circumscribed and painful | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous lipomatous tissue --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous lipomatous tissue | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous nodule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous nodule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous nontender firm nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous nontender firm nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous ossifications --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous ossifications | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous papules in infancy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous papules in infancy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous scalp cysts --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous scalp cysts | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subcutaneous tumors, recurring --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subcutaneous tumors, recurring | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subepidermal capillary ectasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subepidermal capillary ectasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:subungual fibroma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:subungual fibroma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:superficial generalized lifelong skin peeling (sparing palms and soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:superficial generalized lifelong skin peeling (sparing palms and soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:superficial skin peeling (limited to dorsa of hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:superficial skin peeling (limited to dorsa of hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:superficial, firm, circumscribed nodule --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:superficial, firm, circumscribed nodule | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:suppurative scalp nodules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:suppurative scalp nodules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:suprapubic skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:suprapubic skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sweat glands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sweat glands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sweat pore aplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sweat pore aplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:sweating, episodic --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:sweating, episodic | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:symptom/complaint nails --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:symptom/complaint nails | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:symptom/complaint of skin texture --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:symptom/complaint of skin texture | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:systematized epidermal nevus --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:systematized epidermal nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tan macules on glans penis and penile shaft --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tan macules on glans penis and penile shaft | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tanning possible --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tanning possible | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:taunt skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:taunt skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectases (especially on tongue, lips, palate, face, conjunctiva, trunk, nail beds, fingers, and finger pads) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectases (especially on tongue, lips, palate, face, conjunctiva, trunk, nail beds, fingers, and finger pads) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectases (especially on tongue, lips, palate, fingers, face, conjunctiva, trunk, nail beds, and fingertips) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectases (especially on tongue, lips, palate, fingers, face, conjunctiva, trunk, nail beds, and fingertips) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectases (palms, soles, scalp, scrotum, legs) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectases (palms, soles, scalp, scrotum, legs) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectases in sun-exposed and nonexposed skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectases in sun-exposed and nonexposed skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasia (soles) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasia (soles) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasia of photoexposed areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasia of photoexposed areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasia on lips and oral mucosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasia on lips and oral mucosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasia on the cheeks --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasia on the cheeks | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasia, particularly of the fingerpads and lips --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasia, particularly of the fingerpads and lips | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasias in both sun-exposed and sun-protected areas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasias in both sun-exposed and sun-protected areas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectasis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:telangiectatic lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:telangiectatic lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tendency to overheat --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tendency to overheat | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tendinous xanthomas presenting after age 20 years in heterozygotes, during first 4 years of life in homozygotes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tendinous xanthomas presenting after age 20 years in heterozygotes, during first 4 years of life in homozygotes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tenting - skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tenting - skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick calluses on soles of feet --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick calluses on soles of feet | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick facial skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick facial skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick skin (66%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick skin (66%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick skin (74%) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick skin (74%) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick skin on face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick skin on face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick, calloused skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick, calloused skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick, indurated skin over entire body --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick, indurated skin over entire body | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick, loose, doughy skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick, loose, doughy skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick, relatively tight skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick, relatively tight skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thick, waxy skin of palms and soles with well-defined erythematous border --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thick, waxy skin of palms and soles with well-defined erythematous border | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickened nuchal skin fold --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickened nuchal skin fold | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickened skin over flexor surface of proximal phalanges --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickened skin over flexor surface of proximal phalanges | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickened skin over the elbows and along the fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickened skin over the elbows and along the fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickened, furrowed skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickened, furrowed skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickening of skin on the plantar and palmar surfaces --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickening of skin on the plantar and palmar surfaces | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thickening of the skin over the palms and soles (nola3 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thickening of the skin over the palms and soles (nola3 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin translucent skin (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin translucent skin (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, dry skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, dry skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, hyperpigmented skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, hyperpigmented skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, hypotrophic skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, hypotrophic skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, translucent skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, translucent skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, transparent skin (hands and feet) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, transparent skin (hands and feet) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, velvety skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, velvety skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:thin, wrinkled skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:thin, wrinkled skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tight, glistening facial skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tight, glistening facial skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tight, rigid skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tight, rigid skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tight, shiny skin over the forearms and hands --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tight, shiny skin over the forearms and hands | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tinea capitis, severe or recurrent --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tinea capitis, severe or recurrent | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tone does not appreciably change with age --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tone does not appreciably change with age | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transgression of hyperkeratosis to dorsum of hands and feet (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transgression of hyperkeratosis to dorsum of hands and feet (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transgressive keratosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transgressive keratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transient eczema --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transient eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transient erysipelas-like erythematous rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transient erysipelas-like erythematous rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transient painful erysipelas-like lesions on lower leg and ankle --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transient painful erysipelas-like lesions on lower leg and ankle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transient, migratory sharply outlined erythema (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transient, migratory sharply outlined erythema (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transitional zone of cells with gradual loss of nuclei --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transitional zone of cells with gradual loss of nuclei | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transparent skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transparent skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transplanted skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transplanted skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:transverse distal crease across palm --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:transverse distal crease across palm | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:trichilemmal cyst --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:trichilemmal cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:trichoepithelioma (brown, flat-topped papules) (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:trichoepithelioma (brown, flat-topped papules) (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:trichoepitheliomas, multiple (usually occur in the nasolabial folds, nose, or face) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:trichoepitheliomas, multiple (usually occur in the nasolabial folds, nose, or face) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:trichoepitheliomas, multiple (usually occur in thenasolabial folds, the nose, and upper lip) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:trichoepitheliomas, multiple (usually occur in thenasolabial folds, the nose, and upper lip) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tuberous xanthoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tuberous xanthoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tumors appear most often on sun-exposed regions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tumors appear most often on sun-exposed regions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tumors are locally invasive --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tumors are locally invasive | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tumors leave pitting scars --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tumors leave pitting scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:tumors undergo spontaneous resolution over a period of months --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:tumors undergo spontaneous resolution over a period of months | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcer --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcer | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcerations of distal extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcerations of distal extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcers often lead to infection and amputation --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcers often lead to infection and amputation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcers, distal, due to sensory neuropathy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcers, distal, due to sensory neuropathy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcers, distal, painless, due to sensory neuropathy --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcers, distal, painless, due to sensory neuropathy | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:ulcers, plantar --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:ulcers, plantar | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:umbilical bleeding after birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:umbilical bleeding after birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:unilateral erythema and scaling (present at birth or soon after birth, face is spared) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:unilateral erythema and scaling (present at birth or soon after birth, face is spared) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:unprovoked bruising --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:unprovoked bruising | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:uric acid tophi --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:uric acid tophi | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:urticaria --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:urticaria | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:urticaria due to cold --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:urticaria due to cold | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:urticaria pigmentosa --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:urticaria pigmentosa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:urticaria pigmentosa or cutaneous mastocytosis (in patients with kit mutations) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:urticaria pigmentosa or cutaneous mastocytosis (in patients with kit mutations) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:usually occurs in the head and neck area --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:usually occurs in the head and neck area | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:usually present on skin of neck, shoulders, or trunk --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:usually present on skin of neck, shoulders, or trunk | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:variable involvement of palms and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:variable involvement of palms and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:variable number of lesions (1 to greater than 10) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:variable number of lesions (1 to greater than 10) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:variable skin syndactyly fingers and toes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:variable skin syndactyly fingers and toes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:varicose veins (reported in 1 family) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:varicose veins (reported in 1 family) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:varicosity --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:varicosity | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vasculitis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vasculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vasculitis rash --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vasculitis rash | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:velvety skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:velvety skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:velvety texture --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:velvety texture | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:velvety, smooth skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:velvety, smooth skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:venous angiectasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:venous angiectasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vernix-like skin covering, present at birth, shed during first month of life (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vernix-like skin covering, present at birth, shed during first month of life (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:verrucae (warts), multiple --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:verrucae (warts), multiple | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:verrucous hyperplasia --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:verrucous hyperplasia | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vertical crease in fourth interdigital space --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vertical crease in fourth interdigital space | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vertical creases of plantar surface between first and second toes --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vertical creases of plantar surface between first and second toes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vesicles on scalp and skin filled with clear fluid and less than 1cm in diameter --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vesicles on scalp and skin filled with clear fluid and less than 1cm in diameter | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vesicles, congenital, on fingers and soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vesicles, congenital, on fingers and soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vesicular lesions (inflammatory type b) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vesicular lesions (inflammatory type b) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vesicular lesions, congenital bilateral, between ear and corner of mouth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vesicular lesions, congenital bilateral, between ear and corner of mouth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vesiculopustular lesions --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vesiculopustular lesions | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vessels may form rounded nodules ('tufts') --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vessels may form rounded nodules ('tufts') | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vitiligo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vitiligo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vitiligo (1 patient) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vitiligo (1 patient) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:vitiligo (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:vitiligo (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:warfarin-induced skin necrosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:warfarin-induced skin necrosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:warts --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:warts | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:warts, generalized (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:warts, generalized (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:warty acanthomas --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:warty acanthomas | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:warty thickening of flexural skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:warty thickening of flexural skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:webbing of fingers (rare) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:webbing of fingers (rare) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:well-circumscribed peeling of the skin on the extremities and neck (easily elicited by moisture and minor trauma) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:well-circumscribed peeling of the skin on the extremities and neck (easily elicited by moisture and minor trauma) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:well-defined erythematous border --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:well-defined erythematous border | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:white ash leaf-shaped macules --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:white ash leaf-shaped macules | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:white at birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:white at birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:white dermatographism --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:white dermatographism | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:white scaling skin, most prominent over upper and lower extremities --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:white scaling skin, most prominent over upper and lower extremities | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:white skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:white skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wide, thin scars --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wide, thin scars | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wound healing normal --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wound healing normal | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled abdominal skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled abdominal skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled face --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled face | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled forehead at birth (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled forehead at birth (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled palms --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled palms | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled skin over dorsa of fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled skin over dorsa of fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled skin over fingers --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled skin over fingers | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkled soles --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkled soles | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkling of skin on limbs --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkling of skin on limbs | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkly skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkly skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkly skin (13 of 22) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkly skin (13 of 22) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:wrinkly skin at birth --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:wrinkly skin at birth | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:xanthoma --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:xanthoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:xanthomas (in some patients) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:xanthomas (in some patients) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:xerosis --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:xerosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:xerosis (buttocks, extensor surfaces of extremities) --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:xerosis (buttocks, extensor surfaces of extremities) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:yellow subcutaneous tissue covered by thin, scaly skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:yellow subcutaneous tissue covered by thin, scaly skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:yellow, papular lesions of the lip, soft palate, pharynx --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:yellow, papular lesions of the lip, soft palate, pharynx | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:yellow-orange colored skin --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=en:yellow-orange colored skin | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 kyste pilaire --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=kyste pilaire | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 kyste sébacé --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=kyste sébacé | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 kyste trichilemmal --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=kyste trichilemmal | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 kyste épidermique --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=kyste épidermique | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 kyste épidermoïde --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=kyste épidermoïde | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 peau --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=peau | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 vitiligo --- r_associated #0: 20 --> en:generalized skin thickening (particularly over the trunk) n1=vitiligo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=20 en:proliferating pilar tumor --- r_associated #0: 15 --> en:generalized skin thickening (particularly over the trunk) n1=en:proliferating pilar tumor | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=15 exanthème morbilliforme --- r_associated #0: 15 --> en:generalized skin thickening (particularly over the trunk) n1=exanthème morbilliforme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=15 Erdheim-Chester --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=Erdheim-Chester | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 absorption cutanée --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=absorption cutanée | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 absorption percutanée --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=absorption percutanée | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 acanthosis nigricans --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=acanthosis nigricans | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 acné conglobata --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=acné conglobata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 acrogeria --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=acrogeria | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 albinisme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=albinisme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 albinoïdisme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=albinoïdisme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 angiokeratoma --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=angiokeratoma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 angiome --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=angiome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 atopie --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=atopie | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 cancer cutané --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=cancer cutané | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 cancer de la peau --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=cancer de la peau | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 cavernome --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=cavernome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 cutis laxa --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=cutis laxa | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 cutis marmorata --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=cutis marmorata | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 dermatomycoses --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=dermatomycoses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 dermite séborrhéique de la tête --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=dermite séborrhéique de la tête | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 eczema --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=eczema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 empreintes digitales absentes --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=empreintes digitales absentes | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 en:hyperacanthosis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=en:hyperacanthosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 en:pilar cyst --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=en:pilar cyst | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 folliculitis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=folliculitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hirsutisme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hirsutisme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hyodésoxycholique (acide) --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hyodésoxycholique (acide) | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hyperkeratosis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hyperkeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hyperpigmentation --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hyperpigmentation | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hémangiome --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hémangiome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 hémangiome caverneux --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=hémangiome caverneux | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 ichthyoses --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=ichthyoses | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 impétigo --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=impétigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 intertrigo --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=intertrigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 keratosis pilaris --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=keratosis pilaris | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 knuckle pads --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=knuckle pads | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 kératinocyte --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=kératinocyte | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 kératose en rayon de miel --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=kératose en rayon de miel | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 lichénification --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=lichénification | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 livedo --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=livedo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 livedo reticularis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=livedo reticularis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 livédo --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=livédo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 maladie d'Erdheim-Chester --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=maladie d'Erdheim-Chester | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 malformation caverneuse cérébrale --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=malformation caverneuse cérébrale | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 molluscum contagiosum --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=molluscum contagiosum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 nevus --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=nevus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 palmar pit --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=palmar pit | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 papillomatosis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=papillomatosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 parakeratosis --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=parakeratosis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 petechiae --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=petechiae | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 piebaldisme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=piebaldisme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 pityriasis alba --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=pityriasis alba | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 piébaldisme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=piébaldisme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 plis de flexion anormaux des doigts --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=plis de flexion anormaux des doigts | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 poikiloderma --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=poikiloderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 prurigo --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=prurigo | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 pruritus --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=pruritus | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 purpura --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=purpura | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 pyoderma gangrenosum --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=pyoderma gangrenosum | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 schwannogliome --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=schwannogliome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 sclérodactylie --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=sclérodactylie | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 skin tag --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=skin tag | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 steatocystoma multiplex --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=steatocystoma multiplex | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 tumeur maligne de la peau --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=tumeur maligne de la peau | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 varicosité --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=varicosité | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 vascularite --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=vascularite | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 Épidermolyse bulleuse jonctionnelle --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=Épidermolyse bulleuse jonctionnelle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 épidermolyse bulleuse jonctionnelle --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=épidermolyse bulleuse jonctionnelle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 éruption cutanée morbilliforme --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=éruption cutanée morbilliforme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 érythème fessier --- r_associated #0: 10 --> en:generalized skin thickening (particularly over the trunk) n1=érythème fessier | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=10 angiome caverneux --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=angiome caverneux | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 candidiasis --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=candidiasis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 cicatrice hypertrophique --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=cicatrice hypertrophique | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 cutis marmorata telangiectatica congenita --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=cutis marmorata telangiectatica congenita | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 dermatite --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=dermatite | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 dermatitis --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=dermatitis | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 dermite herpétiforme --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=dermite herpétiforme | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 en:cavernous hemangioma --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=en:cavernous hemangioma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 en:malignant skin neoplasm --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=en:malignant skin neoplasm | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 exanthema --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=exanthema | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 fistule entérocutanée --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=fistule entérocutanée | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 ichthyose congénitale --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=ichthyose congénitale | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 kyste de kératine --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=kyste de kératine | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 kyste dentigère --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=kyste dentigère | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 kyste folliculaire --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=kyste folliculaire | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 kyste gingival --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=kyste gingival | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 kyste tapissé d'épithélium --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=kyste tapissé d'épithélium | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 lipome --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=lipome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 neurinome --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=neurinome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 pyoderma --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=pyoderma | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 péliose --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=péliose | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 pénétration percutanée --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=pénétration percutanée | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 schwannome --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=schwannome | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5 érysipèle --- r_associated #0: 5 --> en:generalized skin thickening (particularly over the trunk) n1=érysipèle | n2=en:generalized skin thickening (particularly over the trunk) | rel=r_associated | relid=0 | w=5