1. [noun] A weariness caused by exertion; exhaustion.
2. [noun] A menial task, especially in the military.
3. [noun] (engineering) A mechanism of material failure involving of crack growth caused by low-stress cyclic loading.
4. [verb] (transitive) to tire or make weary by physical or mental exertion
5. [verb] (intransitive) to lose so much strength or energy that one becomes tired, weary, feeble or exhausted
6. [verb] (intransitive) (engineering) (of a material specimen) to undergo the process of fatigue; to fail as a result of fatigue.
7. [noun] Temporary loss of strength and energy resulting from hard physical or mental work; 'he was hospitalized for extreme fatigue'; 'growing fatigue was apparent from the decline in the execution of their athletic skills'; 'weariness overcame her after twelve hours and she fell asleep'.
8. [noun] Used of materials (especially metals) in a weakened state caused by long stress; 'metal fatigue'.
9. [noun] (always used with a modifier) boredom resulting from overexposure to something; 'he was suffering from museum fatigue'; 'after watching TV with her husband she had a bad case of football fatigue'; 'the American public is experiencing scandal fatigue'; 'political fatigue'.
10. [noun] Labor of a nonmilitary kind done by soldiers (cleaning or digging or draining or so on); 'the soldiers were put on fatigue to teach them a lesson'; 'they were assigned to kitchen fatigues'.
11. [verb] Lose interest or become bored with something or somebody; 'I'm so tired of your mother and her complaints about my food'.
12. [verb] Exhaust or get tired through overuse or great strain or stress; 'We wore ourselves out on this hike'.