1. [noun] The result of being impaired; a deterioration or weakening; a disability or handicap; an inefficient part or factor.
2. [noun] (accounting) A downward revaluation, a write-down.
3. [noun] The occurrence of a change for the worse.
4. [noun] A symptom of reduced quality or strength.
5. [noun] The condition of being unable to perform as a consequence of physical or mental unfitness; 'reading disability'; 'hearing impairment'.
6. [noun] Damage that results in a reduction of strength or quality.
7. [noun] The act of making something futile and useless (as by routine).