1. [noun] The act of passing or flowing out; a moving out from any enclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
2. [noun] The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
3. [noun] That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
4. [noun] Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
5. [noun] Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
6. [noun] A discharge of flux, as of blood.
7. [noun] An opening or outlet, providing for an exit or egress.
8. [noun] (medicine) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
9. [noun] The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
10. [noun] A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
11. [noun] (legal) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination.
12. [noun] (finance) A financial instrument in a company, such as a bond, stock or other security; the emission of such an instrument.
13. [noun] (euphemistic) A problem or concern, usually of a mental nature.
14. [noun] An instalment of a periodical; a specific instance of a regular publication
15. [verb] To pass or flow out; to run out, as from any enclosed place.
16. [verb] To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
17. [verb] To proceed, as from a source; as, water issues from springs; light issues from the sun.
18. [verb] To proceed, as progeny; to be derived; to be descended; to spring.
19. [verb] To extend; to pass or open; as, the path issues into the highway.
20. [verb] To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
21. [verb] To turn out (in a given way); to have a specified issue or result, to result (in).
22. [verb] (legal) In pleading, to come to a point in fact or law, on which the parties join issue.
23. [verb] To send out; to put into circulation; as, to issue notes from a bank.
24. [verb] To deliver for use; as, to issue provisions.
25. [verb] To send out officially; to deliver by authority; as, to issue an order; to issue a writ.
26. [noun] A Monacan Indian; a member of a Mestee group originating in Amherst County, Virginia.
27. [noun] An important question that is in dispute and must be settled; 'the issue could be settled by requiring public education for everyone'; 'politicians never discuss the real issues'.
28. [noun] One of a series published periodically; 'she found an old issue of the magazine in her dentist's waiting room'.
29. [noun] Some situation or event that is thought about; 'he kept drifting off the topic'; 'he had been thinking about the subject for several years'; 'it is a matter for the police'.
30. [noun] The act of providing an item for general use or for official purposes (usually in quantity); 'a new issue of stamps'; 'the last issue of penicillin was over a month ago'.
31. [noun] Supplies (as food or clothing or ammunition) issued by the government.
32. [noun] The income or profit arising from such transactions as the sale of land or other property; 'the average return was about 5%'.
33. [noun] A phenomenon that follows and is caused by some previous phenomenon; 'the magnetic effect was greater when the rod was lengthwise'; 'his decision had depressing consequences for business'; 'he acted very wise after the event'.
34. [noun] The immediate descendants of a person; 'she was the mother of many offspring'; 'he died without issue'.
35. [noun] The becoming visible; 'not a day's difference between the emergence of the andrenas and the opening of the willow catkins'.
36. [noun] An opening that permits escape or release; 'he blocked the way out'; 'the canyon had only one issue'.
37. [noun] The act of issuing printed materials.
38. [verb] Prepare and issue for public distribution or sale; 'publish a magazine or newspaper'.
39. [verb] Circulate or distribute or equip with; 'issue a new uniform to the children'; 'supply blankets for the beds'.
40. [verb] Bring out an official document (such as a warrant).
41. [verb] Come out of; 'Water issued from the hole in the wall'; 'The words seemed to come out by themselves'.
42. [verb] Make out and issue; 'write out a check'; 'cut a ticket'; 'Please make the check out to me'.
